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The map label for this gene is asd [H]

Identifier: 218708900

GI number: 218708900

Start: 925329

End: 926342

Strand: Direct

Name: asd [H]

Synonym: VS_0901

Alternate gene names: 218708900

Gene position: 925329-926342 (Clockwise)

Preceding gene: 218708899

Following gene: 218708901

Centisome position: 28.05

GC content: 45.46

Gene sequence:

>1014_bases
ATGAGCCAAGAATTTAATATTGCTATTTTAGGTGCGACTGGTGCGGTTGGTGAAACCATTCTTGAAGTACTTAAAGAGCG
TAAATTCCCTGTCGGTGAAATGCACTTACTAGCAAGTGAACGTAGTGAAGGCAAAACTTCCCGTTTTAACGGCAAAACAA
TACAAGTACAAAACGTAGAAGACTTCGATTGGTCTCAAGTACATATTGCATTTTTCTCTGCAGGTAGCGAGCTTTCAGAA
CGTTGGGCTCCAATCGCCGCTGACGAAGGTGTGGTTGTTATCGATAACACCTCACGTTTCCGTTACGAATACGATGTTCC
TCTGGTTGTGCCTGAAGTGAACCCTGAAGCGATTGCTGAGTTCCGTAATCGCAACATCATTGCGAACCCGAACTGTTCTA
CTATTCAGATGGTAGTAGCACTTAAACCGATTCACGATGAAGTGGGCCTTGAGCGTATTAACGTTTCAACTTACCAATCT
GTGTCTGGTGCAGGTAAGCCGGGTATCGATGAGCTAGCAGGTCAAACGGCTAAGCTTCTTAACGGTATGCCAGCTGACAA
GTCAGCGTTCTCACAGCAGATCGCCTTCAACTGTATTCCTCAAATCGATGAATTTACAGAGAACGGCTACACACGTGAAG
AAATGAAGATGGTTTGGGAAACTCAAAAGATCTTTGCTGATTCATCAATCACGGTTAACCCGACTTGTGTTCGTGTTCCT
GTGTTCTATGGTCACGCTGAATCTCTACACATTGAAACTCGCGCGCCAATCGGTGCTGAGCAAGTTATTCAGCTTCTAGA
GAACACGGAAGGCGTTGAAGTTTTCCAAGCGCTAGACTTCCCAACTCAGGTTCGTGATGCAGGTGGTAAAGACCACGTAA
TGGTTGGTCGTATTCGTAACGACATTAGCCATCACAGCGGTGTGAACATGTGGGTTGTCGCTGATAACGTTCGTAAAGGC
GCAGCAACAAACGCAGTTCAAATCGCGGAAGTTCTGATTCGCGATTACTTCTAA

Upstream 100 bases:

>100_bases
GTACAGTGCAGTCGAGTTAACGGGCGACGAATCTTGTAATTTAACGCCGTTATCTAAACTCGGTTTTATGGTAAAGCCAA
CTTTATAAAAGAGAGAAACA

Downstream 100 bases:

>100_bases
GCTTCACTGCTTTGATAAACAAGCCTCACTCTTTTAGTGGGGCTTTTTTAATCGATTGAAAATATTGTTAGTTAAATTGT
GTGAAATTGCTGCGAATATT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSQEFNIAILGATGAVGETILEVLKERKFPVGEMHLLASERSEGKTSRFNGKTIQVQNVEDFDWSQVHIAFFSAGSELSE
RWAPIAADEGVVVIDNTSRFRYEYDVPLVVPEVNPEAIAEFRNRNIIANPNCSTIQMVVALKPIHDEVGLERINVSTYQS
VSGAGKPGIDELAGQTAKLLNGMPADKSAFSQQIAFNCIPQIDEFTENGYTREEMKMVWETQKIFADSSITVNPTCVRVP
VFYGHAESLHIETRAPIGAEQVIQLLENTEGVEVFQALDFPTQVRDAGGKDHVMVGRIRNDISHHSGVNMWVVADNVRKG
AATNAVQIAEVLIRDYF

Sequences:

>Translated_337_residues
MSQEFNIAILGATGAVGETILEVLKERKFPVGEMHLLASERSEGKTSRFNGKTIQVQNVEDFDWSQVHIAFFSAGSELSE
RWAPIAADEGVVVIDNTSRFRYEYDVPLVVPEVNPEAIAEFRNRNIIANPNCSTIQMVVALKPIHDEVGLERINVSTYQS
VSGAGKPGIDELAGQTAKLLNGMPADKSAFSQQIAFNCIPQIDEFTENGYTREEMKMVWETQKIFADSSITVNPTCVRVP
VFYGHAESLHIETRAPIGAEQVIQLLENTEGVEVFQALDFPTQVRDAGGKDHVMVGRIRNDISHHSGVNMWVVADNVRKG
AATNAVQIAEVLIRDYF
>Mature_336_residues
SQEFNIAILGATGAVGETILEVLKERKFPVGEMHLLASERSEGKTSRFNGKTIQVQNVEDFDWSQVHIAFFSAGSELSER
WAPIAADEGVVVIDNTSRFRYEYDVPLVVPEVNPEAIAEFRNRNIIANPNCSTIQMVVALKPIHDEVGLERINVSTYQSV
SGAGKPGIDELAGQTAKLLNGMPADKSAFSQQIAFNCIPQIDEFTENGYTREEMKMVWETQKIFADSSITVNPTCVRVPV
FYGHAESLHIETRAPIGAEQVIQLLENTEGVEVFQALDFPTQVRDAGGKDHVMVGRIRNDISHHSGVNMWVVADNVRKGA
ATNAVQIAEVLIRDYF

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=338, Percent_Identity=47.3372781065089, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1789841, Length=294, Percent_Identity=25.5102040816327, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320362, Length=390, Percent_Identity=30.7692307692308, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37280; Mature: 37148

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQEFNIAILGATGAVGETILEVLKERKFPVGEMHLLASERSEGKTSRFNGKTIQVQNVE
CCCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCC
DFDWSQVHIAFFSAGSELSERWAPIAADEGVVVIDNTSRFRYEYDVPLVVPEVNPEAIAE
CCCCCEEEEEEEECCHHHHHHCCCCCCCCCEEEEECCCEEEEEECCCEEEECCCHHHHHH
FRNRNIIANPNCSTIQMVVALKPIHDEVGLERINVSTYQSVSGAGKPGIDELAGQTAKLL
HHCCCEEECCCCCEEEEEEEEECCHHHCCCEEECCHHHHHCCCCCCCCHHHHHHHHHHHH
NGMPADKSAFSQQIAFNCIPQIDEFTENGYTREEMKMVWETQKIFADSSITVNPTCVRVP
CCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEECCEEEEEE
VFYGHAESLHIETRAPIGAEQVIQLLENTEGVEVFQALDFPTQVRDAGGKDHVMVGRIRN
EEECCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHCCCCHHHHCCCCCCCEEEEHHHH
DISHHSGVNMWVVADNVRKGAATNAVQIAEVLIRDYF
HHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SQEFNIAILGATGAVGETILEVLKERKFPVGEMHLLASERSEGKTSRFNGKTIQVQNVE
CCCEEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCC
DFDWSQVHIAFFSAGSELSERWAPIAADEGVVVIDNTSRFRYEYDVPLVVPEVNPEAIAE
CCCCCEEEEEEEECCHHHHHHCCCCCCCCCEEEEECCCEEEEEECCCEEEECCCHHHHHH
FRNRNIIANPNCSTIQMVVALKPIHDEVGLERINVSTYQSVSGAGKPGIDELAGQTAKLL
HHCCCEEECCCCCEEEEEEEEECCHHHCCCEEECCHHHHHCCCCCCCCHHHHHHHHHHHH
NGMPADKSAFSQQIAFNCIPQIDEFTENGYTREEMKMVWETQKIFADSSITVNPTCVRVP
CCCCCCHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEECCEEEEEE
VFYGHAESLHIETRAPIGAEQVIQLLENTEGVEVFQALDFPTQVRDAGGKDHVMVGRIRN
EEECCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHCCCCHHHHCCCCCCCEEEEHHHH
DISHHSGVNMWVVADNVRKGAATNAVQIAEVLIRDYF
HHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]