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The map label for this gene is sixA-A [H]

Identifier: 218708867

GI number: 218708867

Start: 891622

End: 892086

Strand: Direct

Name: sixA-A [H]

Synonym: VS_0867

Alternate gene names: 218708867

Gene position: 891622-892086 (Clockwise)

Preceding gene: 218708865

Following gene: 218708869

Centisome position: 27.02

GC content: 44.09

Gene sequence:

>465_bases
ATGAAAATATTCATAATGCGCCACGGTGAAGCAGAACATTTTGCTAACTCGGATGCAGAACGTGCGTTAACGAAGCGCGG
TAAAATGGCGTCTCTTGCGGTAGCTCAAGCTGCAAATGAGCAAGGGTTTAGCCAGTTCGATAAAGTGCTTGTGAGCCCAT
ACTTAAGGGCACAAGAAACGTGGTTAGAAATCTCTCAAGCGTTTTCTGGAAAGAAAGTAGAAACCTGTGATGATATTACG
CCTTACGGAATGTCCGACGATGTGTTTGATTTGACCATAGCAATGGCTGAAGTAGAAAAGCTAGAGACCATTTTATTTGT
TTCTCATTTACCTCTAGTGGGCTATTTAACGGCTGAATTTGCGACGGGCATGGCGCCACCTATGTTCCCAACCTCAGGGC
TCGCGTGTATTGAATTCGACCTTGAAAAACAAAAAGGCGAGTTGCTTTGGAACATTAATCCATAG

Upstream 100 bases:

>100_bases
ATAGACTGCGGTTTCTCTAGTTTGAGAGCCAAACGCTAAGTAGCGTATCGCTGATATGGGATATATCGACTTTCGAAATG
TTACGTAGACAGGACTGAAC

Downstream 100 bases:

>100_bases
CTGAGACCGTTTTCTCAAGATAAATTTAAGGGCACCTCATGATTATTGAGATGCCCTTTATTGTTTCTAACGGATTATTT
CGACCAAACGACAAGGTGCT

Product: phosphohistidine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MKIFIMRHGEAEHFANSDAERALTKRGKMASLAVAQAANEQGFSQFDKVLVSPYLRAQETWLEISQAFSGKKVETCDDIT
PYGMSDDVFDLTIAMAEVEKLETILFVSHLPLVGYLTAEFATGMAPPMFPTSGLACIEFDLEKQKGELLWNINP

Sequences:

>Translated_154_residues
MKIFIMRHGEAEHFANSDAERALTKRGKMASLAVAQAANEQGFSQFDKVLVSPYLRAQETWLEISQAFSGKKVETCDDIT
PYGMSDDVFDLTIAMAEVEKLETILFVSHLPLVGYLTAEFATGMAPPMFPTSGLACIEFDLEKQKGELLWNINP
>Mature_154_residues
MKIFIMRHGEAEHFANSDAERALTKRGKMASLAVAQAANEQGFSQFDKVLVSPYLRAQETWLEISQAFSGKKVETCDDIT
PYGMSDDVFDLTIAMAEVEKLETILFVSHLPLVGYLTAEFATGMAPPMFPTSGLACIEFDLEKQKGELLWNINP

Specific function: Exhibits Phosphohistidine Phosphatase Activity Towards The Hpt Domain Of The Arcb Sensor Involved In The Multistep His- Asp Phosphorelay. [C]

COG id: COG2062

COG function: function code T; Phosphohistidine phosphatase SixA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sixA phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788681, Length=155, Percent_Identity=38.7096774193548, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR004449 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: 3.1.3.- [C]

Molecular weight: Translated: 17111; Mature: 17111

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIFIMRHGEAEHFANSDAERALTKRGKMASLAVAQAANEQGFSQFDKVLVSPYLRAQET
CEEEEEECCCHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
WLEISQAFSGKKVETCDDITPYGMSDDVFDLTIAMAEVEKLETILFVSHLPLVGYLTAEF
HHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ATGMAPPMFPTSGLACIEFDLEKQKGELLWNINP
HCCCCCCCCCCCCEEEEEEEECCCCCCEEEECCC
>Mature Secondary Structure
MKIFIMRHGEAEHFANSDAERALTKRGKMASLAVAQAANEQGFSQFDKVLVSPYLRAQET
CEEEEEECCCHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
WLEISQAFSGKKVETCDDITPYGMSDDVFDLTIAMAEVEKLETILFVSHLPLVGYLTAEF
HHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ATGMAPPMFPTSGLACIEFDLEKQKGELLWNINP
HCCCCCCCCCCCCEEEEEEEECCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]