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The map label for this gene is mraY [H]

Identifier: 218708483

GI number: 218708483

Start: 457439

End: 458521

Strand: Direct

Name: mraY [H]

Synonym: VS_0447

Alternate gene names: 218708483

Gene position: 457439-458521 (Clockwise)

Preceding gene: 218708482

Following gene: 218708484

Centisome position: 13.86

GC content: 46.54

Gene sequence:

>1083_bases
ATGATAATTTGGCTTGCAGAGCTACTACAGCCACACTTTTCTTTTTTCCGTTTGTTCGAATACTTATCGTTTCGTGCAAT
CGCGAGTATTTTGACGGCGTTATGTCTGTCACTGTGGATGGGACCTCGTTTAATTGAGCGTCTGCAAATGCTACAAATTG
GCCAAGTTGTTCGTAATGACGGCCCTGAATCTCATTTCAGCAAACGTGGCACGCCAACCATGGGCGGTGTGATGATCCTT
GCTGCGATCATTATTACGGTATTGATGTGGGCTGATCTCTCGAATCCTTATGTTTGGGCTGTATTAGTTGTACTTGCTGG
TTATGGCGCGGTTGGCTTTGTTGATGACTACCGTAAAGTGGTTCGCAAAAACACAGATGGCTTGATAGCTCGCTGGAAGT
ACTTCTGGCAATCAGCTATTGCGTTAGTCGTGGCGTTTGCTCTGTATGCTCACGGGCACGATACTGCAGCAACTCAATTG
GTTGTTCCTTTCTTTAAAGATGTGATGCCACAACTTGGTTTACTGTATATCGTACTAACTTACTTTGTTATTGTGGGAAC
CAGTAACGCGGTAAACCTAACAGACGGCCTAGACGGCTTGGCCATTATGCCAACGGTTATGGTTGCGGCTGGTTTTGCTG
TAATTGCTTGGGCGACCGGTAACGTTAACTTTGCGTCATACTTACACATTCCATACATCCCATACACCTCCGAGCTGGTT
GTGGTATGTACTGCTATCGTAGGTGCTGGACTTGGTTTTCTATGGTTCAACACTTATCCTGCACAAGTATTCATGGGCGA
TGTTGGCTCACTAGCGCTTGGTGGTGCTCTGGGTGTGATCGCTGTGTTAGTTCGCCAAGAGTTGGTATTGGTTATCATGG
GCGGTGTGTTTGTAATGGAGACCTTGTCAGTGATACTGCAAGTTGGCTCTTACAAATTGCGCGGTCAGCGTATTTTCCGC
ATGGCACCAATTCACCACCACTATGAACTGAAAGGTTGGCCGGAGCCACGTGTCATCGTGCGTTTTTGGATCATCTCAAT
GGTATTAGTACTGGTTGGCCTAGCAACGCTGAAAGTTCGTTAA

Upstream 100 bases:

>100_bases
ACCTAAGCTTGCCAGAAAGCGTGTCACATACCTTATTGGTAAAAGGCGCGAATAGTGCAGGAATGAGTAAAATAGCCGCT
GCTTTAAAGGAGAACTTTTC

Downstream 100 bases:

>100_bases
TCCTATGTGAGCCTCTTAATTAGAGGCTCTTTAAAACTATTAAGAGCATCTTGTTTAAATGGAACGTTGGCAAAATATTC
AAAATGTAGTGGTTGTGGGG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MIIWLAELLQPHFSFFRLFEYLSFRAIASILTALCLSLWMGPRLIERLQMLQIGQVVRNDGPESHFSKRGTPTMGGVMIL
AAIIITVLMWADLSNPYVWAVLVVLAGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSAIALVVAFALYAHGHDTAATQL
VVPFFKDVMPQLGLLYIVLTYFVIVGTSNAVNLTDGLDGLAIMPTVMVAAGFAVIAWATGNVNFASYLHIPYIPYTSELV
VVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGVIAVLVRQELVLVIMGGVFVMETLSVILQVGSYKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISMVLVLVGLATLKVR

Sequences:

>Translated_360_residues
MIIWLAELLQPHFSFFRLFEYLSFRAIASILTALCLSLWMGPRLIERLQMLQIGQVVRNDGPESHFSKRGTPTMGGVMIL
AAIIITVLMWADLSNPYVWAVLVVLAGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSAIALVVAFALYAHGHDTAATQL
VVPFFKDVMPQLGLLYIVLTYFVIVGTSNAVNLTDGLDGLAIMPTVMVAAGFAVIAWATGNVNFASYLHIPYIPYTSELV
VVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGVIAVLVRQELVLVIMGGVFVMETLSVILQVGSYKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISMVLVLVGLATLKVR
>Mature_360_residues
MIIWLAELLQPHFSFFRLFEYLSFRAIASILTALCLSLWMGPRLIERLQMLQIGQVVRNDGPESHFSKRGTPTMGGVMIL
AAIIITVLMWADLSNPYVWAVLVVLAGYGAVGFVDDYRKVVRKNTDGLIARWKYFWQSAIALVVAFALYAHGHDTAATQL
VVPFFKDVMPQLGLLYIVLTYFVIVGTSNAVNLTDGLDGLAIMPTVMVAAGFAVIAWATGNVNFASYLHIPYIPYTSELV
VVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGVIAVLVRQELVLVIMGGVFVMETLSVILQVGSYKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISMVLVLVGLATLKVR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=360, Percent_Identity=81.6666666666667, Blast_Score=583, Evalue=1e-168,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 39799; Mature: 39799

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIWLAELLQPHFSFFRLFEYLSFRAIASILTALCLSLWMGPRLIERLQMLQIGQVVRND
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
GPESHFSKRGTPTMGGVMILAAIIITVLMWADLSNPYVWAVLVVLAGYGAVGFVDDYRKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
VRKNTDGLIARWKYFWQSAIALVVAFALYAHGHDTAATQLVVPFFKDVMPQLGLLYIVLT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YFVIVGTSNAVNLTDGLDGLAIMPTVMVAAGFAVIAWATGNVNFASYLHIPYIPYTSELV
HHHHHCCCCCEECCCCCCCHHHHHHHHHHCCHHEEEEECCCCCEEEEEECCCCCCHHHHH
VVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGVIAVLVRQELVLVIMGGVFVME
HHHHHHHHCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISMVLVLVGLATLKVR
HHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIIWLAELLQPHFSFFRLFEYLSFRAIASILTALCLSLWMGPRLIERLQMLQIGQVVRND
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
GPESHFSKRGTPTMGGVMILAAIIITVLMWADLSNPYVWAVLVVLAGYGAVGFVDDYRKV
CCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHH
VRKNTDGLIARWKYFWQSAIALVVAFALYAHGHDTAATQLVVPFFKDVMPQLGLLYIVLT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YFVIVGTSNAVNLTDGLDGLAIMPTVMVAAGFAVIAWATGNVNFASYLHIPYIPYTSELV
HHHHHCCCCCEECCCCCCCHHHHHHHHHHCCHHEEEEECCCCCEEEEEECCCCCCHHHHH
VVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGVIAVLVRQELVLVIMGGVFVME
HHHHHHHHCCHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLSVILQVGSYKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISMVLVLVGLATLKVR
HHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA