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The map label for this gene is icc [H]

Identifier: 218708458

GI number: 218708458

Start: 430519

End: 431343

Strand: Direct

Name: icc [H]

Synonym: VS_0421

Alternate gene names: 218708458

Gene position: 430519-431343 (Clockwise)

Preceding gene: 218708457

Following gene: 218708459

Centisome position: 13.05

GC content: 43.64

Gene sequence:

>825_bases
TTGGAATTATCACACACTTCAAAATTTGATGAGAGCAGTATTAAGCTTGTACAGCTAACGGACACGCATTTATTTGCGCC
GAGCAATGGCAGCTTATTAAGCATCAACACTCAAGATAGCTTTCGTGCTGTAGTCGATGCCATTGTTAGTCAGGGCTTTG
ACTATCAAGCGATTTTAGCAACCGGTGATATTTCTCAAGATCACAGTGCTGAGTCGTACCAAAAATTTGAGTCAGGAATT
CAACCTTTGGATAAACCGTGTTACTGGTTGCCAGGGAATCATGACTTCAAACCGAATATGGGCAGTGTTTTACCATCACC
ACAAATACAATGCGTTGAGCATGTCTTGCTAGGTAATAATTGGCAGATGGTGATGCTGGACTCGCAAGTGGTTGGTGTGC
CTCACGGACGTCTCAGTGATCAACAGCTTGATCTATTAGAACAAAAGCTAACCGAATTTCCCGAACGTAATACCTTGGTT
CTGCTGCACCACCATCCACTATTGGTTGGCAGTGCATGGCTGGATCAACATAATCTGAAAGATGCTGATCAATTTTGGGA
AGTGGTTCAACAGCACACCAATGTGAAAGCGGTACTGTGTGGTCACGTTCATCAAGACATGAATCGAGATCATCATGGTG
TACAAGTCATGGCAACACCGTCGACTTGTGTGCAATTCAAACCTAACTCAGATGACTTTGCGGTTGATACTTTGTCGCCT
GGTTGGAGAGAGATTGAATTGCATCAAGATGGATCAGTAAGTACGCAAGTACGCCGTTTACCTCATGGACAATTCTTACC
TGATTTTGAAGCGGCAGGTTATTGA

Upstream 100 bases:

>100_bases
GTTTAAAAACGGGCATCAGCCGAACTCCAGTTTCTTTTTAATTGAGCCTATTTAAAAACACTTTTAAAGTCTAAACAGTA
ACGTATCTGGATTTGTTATT

Downstream 100 bases:

>100_bases
TGTTTGACTCTGAACAGCAAGCCGCTAAGCCGCCACTGCTTCTCTATATTCACGGTTTTAACAGTTCATCACGTTCTCAC
AAAGCAACGGTGATGGCTGA

Product: cyclic 3',5'-adenosine monophosphate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDAIVSQGFDYQAILATGDISQDHSAESYQKFESGI
QPLDKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGNNWQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLV
LLHHHPLLVGSAWLDQHNLKDADQFWEVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGSVSTQVRRLPHGQFLPDFEAAGY

Sequences:

>Translated_274_residues
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDAIVSQGFDYQAILATGDISQDHSAESYQKFESGI
QPLDKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGNNWQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLV
LLHHHPLLVGSAWLDQHNLKDADQFWEVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGSVSTQVRRLPHGQFLPDFEAAGY
>Mature_274_residues
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDAIVSQGFDYQAILATGDISQDHSAESYQKFESGI
QPLDKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGNNWQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLV
LLHHHPLLVGSAWLDQHNLKDADQFWEVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
GWREIELHQDGSVSTQVRRLPHGQFLPDFEAAGY

Specific function: Affects The Expression Of The Lacz Gene. [C]

COG id: COG1409

COG function: function code R; Predicted phosphohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli icc [H]

Homologues:

Organism=Escherichia coli, GI1789410, Length=264, Percent_Identity=49.6212121212121, Blast_Score=270, Evalue=6e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013622
- InterPro:   IPR004843
- ProDom:   PD587589 [H]

Pfam domain/function: PF00149 Metallophos; PF08413 Metallophos_C [H]

EC number: NA

Molecular weight: Translated: 30747; Mature: 30747

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDAIVSQGFDYQAILA
CCCCCCCCCCCCCEEEEEEECCEEECCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEE
TGDISQDHSAESYQKFESGIQPLDKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGNN
ECCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
EEEEEECCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEHHHHCCCCCC
DADQFWEVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
CHHHHHHHHHHCCCEEEEEEHHHHHHCCCCCCCEEEEECCCEEEEECCCCCCEEEECCCC
GWREIELHQDGSVSTQVRRLPHGQFLPDFEAAGY
CCEEEEEECCCCHHHHHHHCCCCCCCCCHHCCCC
>Mature Secondary Structure
MELSHTSKFDESSIKLVQLTDTHLFAPSNGSLLSINTQDSFRAVVDAIVSQGFDYQAILA
CCCCCCCCCCCCCEEEEEEECCEEECCCCCCEEEEECCHHHHHHHHHHHHCCCCEEEEEE
TGDISQDHSAESYQKFESGIQPLDKPCYWLPGNHDFKPNMGSVLPSPQIQCVEHVLLGNN
ECCCCCCCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCC
WQMVMLDSQVVGVPHGRLSDQQLDLLEQKLTEFPERNTLVLLHHHPLLVGSAWLDQHNLK
EEEEEECCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEHHHHCCCCCC
DADQFWEVVQQHTNVKAVLCGHVHQDMNRDHHGVQVMATPSTCVQFKPNSDDFAVDTLSP
CHHHHHHHHHHCCCEEEEEEHHHHHHCCCCCCCEEEEECCCEEEEECCCCCCEEEECCCC
GWREIELHQDGSVSTQVRRLPHGQFLPDFEAAGY
CCEEEEEECCCCHHHHHHHCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]