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The map label for this gene is mreD [H]

Identifier: 218708383

GI number: 218708383

Start: 338774

End: 339262

Strand: Direct

Name: mreD [H]

Synonym: VS_0343

Alternate gene names: 218708383

Gene position: 338774-339262 (Clockwise)

Preceding gene: 218708382

Following gene: 218708384

Centisome position: 10.27

GC content: 41.1

Gene sequence:

>489_bases
ATGGCCAATAGCGTTTTAAGAAGCAAAGTAGTAATTGGCTGCTCATTTTTGATAGCACTTATTCTACAAACGATCCCTTG
GCCGGGTAGTTTAGACCTATTCAGGCCATCTTGGTTATTACTGGTTACCTGCTATTGGGTTTTAGCGTTACCTTACAGAG
TTAACGTTGGTAGTGCTCTAGTACTGGGCTTATTGTGGGACCTTTTGATCGGTTCGACTCTCGGTATTAGAGGCATGATG
ATGGCAATAGTAATGTACATTATTGCAATGAACTTCCTCGTGATTCGAAATATGGCGCTATGGCAGCAAGCGATAATCAT
TGCAGCTTTAACAGTGTTGTTTGAGGTGCTGATATTCTTTGGTGAATATTTGATCCAAGATGTCGTTTTCAATCCGTTAT
CGCTATGGAGCGCATTGATAAACTGTATACTTTGGCCTTGGATGTTTTTATTAATGAGACGTGTACGTCGCCATTGGCAT
GTAAGGTAG

Upstream 100 bases:

>100_bases
TTTGATAAGCTCAGATACTTGTTGCTTGTGTGGCCTGATGAAAATAAACAGATGCAAGCAGAACAATCCAGTATCGAACA
AGCATTGTTAGAAGGTGAAA

Downstream 100 bases:

>100_bases
AGTGACGATGGAAAAGAAACATTTAGTTTTGGCATCCGGCTCTCCACGCCGCAAAGAATTGCTATCTCAACTCGGTTATG
AGTTTTCTGTCCTTGTAACT

Product: rod shape-determining protein MreD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MANSVLRSKVVIGCSFLIALILQTIPWPGSLDLFRPSWLLLVTCYWVLALPYRVNVGSALVLGLLWDLLIGSTLGIRGMM
MAIVMYIIAMNFLVIRNMALWQQAIIIAALTVLFEVLIFFGEYLIQDVVFNPLSLWSALINCILWPWMFLLMRRVRRHWH
VR

Sequences:

>Translated_162_residues
MANSVLRSKVVIGCSFLIALILQTIPWPGSLDLFRPSWLLLVTCYWVLALPYRVNVGSALVLGLLWDLLIGSTLGIRGMM
MAIVMYIIAMNFLVIRNMALWQQAIIIAALTVLFEVLIFFGEYLIQDVVFNPLSLWSALINCILWPWMFLLMRRVRRHWH
VR
>Mature_161_residues
ANSVLRSKVVIGCSFLIALILQTIPWPGSLDLFRPSWLLLVTCYWVLALPYRVNVGSALVLGLLWDLLIGSTLGIRGMMM
AIVMYIIAMNFLVIRNMALWQQAIIIAALTVLFEVLIFFGEYLIQDVVFNPLSLWSALINCILWPWMFLLMRRVRRHWHV
R

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG2891

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreD family [H]

Homologues:

Organism=Escherichia coli, GI1789647, Length=162, Percent_Identity=47.5308641975309, Blast_Score=162, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007227 [H]

Pfam domain/function: PF04093 MreD [H]

EC number: NA

Molecular weight: Translated: 18693; Mature: 18562

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANSVLRSKVVIGCSFLIALILQTIPWPGSLDLFRPSWLLLVTCYWVLALPYRVNVGSAL
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHH
VLGLLWDLLIGSTLGIRGMMMAIVMYIIAMNFLVIRNMALWQQAIIIAALTVLFEVLIFF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEYLIQDVVFNPLSLWSALINCILWPWMFLLMRRVRRHWHVR
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANSVLRSKVVIGCSFLIALILQTIPWPGSLDLFRPSWLLLVTCYWVLALPYRVNVGSAL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHH
VLGLLWDLLIGSTLGIRGMMMAIVMYIIAMNFLVIRNMALWQQAIIIAALTVLFEVLIFF
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEYLIQDVVFNPLSLWSALINCILWPWMFLLMRRVRRHWHVR
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]