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The map label for this gene is mreB [H]

Identifier: 218708381

GI number: 218708381

Start: 336759

End: 337802

Strand: Direct

Name: mreB [H]

Synonym: VS_0341

Alternate gene names: 218708381

Gene position: 336759-337802 (Clockwise)

Preceding gene: 218708380

Following gene: 218708382

Centisome position: 10.21

GC content: 47.41

Gene sequence:

>1044_bases
ATGTTTAAAAAGCTTCGTGGCATGTTTTCAAACGACCTATCGATTGATTTAGGTACTGCCAATACCCTTATATATGTAAA
AGGCCAAGGCATTGTTCTTGATGAGCCTTCAGTTGTAGCTATCCGCCAAGATCGTGCGGGTTCTGCAAAGAGTGTCGCTG
CGGTTGGTCACGCTGCTAAGCAAATGCTTGGCCGTACGCCTGGTAATATCTCAGCAATCCGTCCAATGAAAGACGGCGTA
ATTGCTGACTTTTACGTAACGGAAAAAATGCTTCAGCACTTCATTAAGCAAGTGCATGATAACAGTGTTCTTAAACCAAG
CCCTCGCGTATTGGTTTGTGTTCCTTGTGGTTCAACGCAAGTTGAGCGCCGTGCAATCCGTGAATCAGCACTGGGTGCTG
GTGCTCGTGAGGTTTACCTAATCGATGAGCCTATGGCTGCTGCGATTGGTGCAGGCCTACGTGTATCTGAGCCAACAGGT
TCAATGGTTGTTGATATCGGTGGTGGTACGACTGAAGTTGCGGTTATCTCACTAAACGGTGTGGTTTACTCCTCTTCTGT
ACGTATCGGTGGTGACCGTTTTGATGAAGCTATCATCAACTACGTTCGTCGTAACTACGGCAGCTTGATCGGTGAAGCAA
CAGCCGAAAAGATCAAACACGAAATCGGTTCTGCTTACCCCGGCGATGAAGTCGATGAGATTGAAGTACGTGGTCGTAAC
CTTGCTGAAGGTGTTCCTCGTAGCTTTAGCCTGAACTCAAATGAAATCCTTGAAGCGCTTCAAGAACCTTTATCTGGCAT
CGTATCTGCAGTCATGGTGGCACTTGAACAGTGTCCACCAGAGCTTGCTTCTGATATCTCAGAAAACGGTATGGTACTGA
CAGGTGGTGGTGCACTGCTTAAAGACCTTGATCGTCTGCTAACTGAAGAAACGGGTATCCCTGTTGTTGTGGCGGAAGAG
CCATTAACGTGTGTTGCTCTAGGCGGTGGTAAAGCTCTAGAGATGATCGACATGCACGGCGGTGATCTTTTCAGCGAAGA
ATAG

Upstream 100 bases:

>100_bases
TCAGTCCATGTTTATACTTCAATGCCTTGCCGTGACAGCAAGGCATTGGTACATTTAGTGCAATTTTTGTCTTCTAATTC
TTGCAGGATGAGCGAAGAAT

Downstream 100 bases:

>100_bases
TATCTAGTGTTAGGCTCTTTTCTTATCTAGTTTTATGTAAAGAGCCTAACACCTTGTCTATAGGATCAAATGTCGCTCTA
GGACCAAATATAGAATGAAG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDRAGSAKSVAAVGHAAKQMLGRTPGNISAIRPMKDGV
IADFYVTEKMLQHFIKQVHDNSVLKPSPRVLVCVPCGSTQVERRAIRESALGAGAREVYLIDEPMAAAIGAGLRVSEPTG
SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAEKIKHEIGSAYPGDEVDEIEVRGRN
LAEGVPRSFSLNSNEILEALQEPLSGIVSAVMVALEQCPPELASDISENGMVLTGGGALLKDLDRLLTEETGIPVVVAEE
PLTCVALGGGKALEMIDMHGGDLFSEE

Sequences:

>Translated_347_residues
MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDRAGSAKSVAAVGHAAKQMLGRTPGNISAIRPMKDGV
IADFYVTEKMLQHFIKQVHDNSVLKPSPRVLVCVPCGSTQVERRAIRESALGAGAREVYLIDEPMAAAIGAGLRVSEPTG
SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAEKIKHEIGSAYPGDEVDEIEVRGRN
LAEGVPRSFSLNSNEILEALQEPLSGIVSAVMVALEQCPPELASDISENGMVLTGGGALLKDLDRLLTEETGIPVVVAEE
PLTCVALGGGKALEMIDMHGGDLFSEE
>Mature_347_residues
MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDRAGSAKSVAAVGHAAKQMLGRTPGNISAIRPMKDGV
IADFYVTEKMLQHFIKQVHDNSVLKPSPRVLVCVPCGSTQVERRAIRESALGAGAREVYLIDEPMAAAIGAGLRVSEPTG
SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAEKIKHEIGSAYPGDEVDEIEVRGRN
LAEGVPRSFSLNSNEILEALQEPLSGIVSAVMVALEQCPPELASDISENGMVLTGGGALLKDLDRLLTEETGIPVVVAEE
PLTCVALGGGKALEMIDMHGGDLFSEE

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=347, Percent_Identity=91.64265129683, Blast_Score=640, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6324120, Length=363, Percent_Identity=23.1404958677686, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319972, Length=363, Percent_Identity=22.5895316804408, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36747; Mature: 36747

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDRAGSAKSVAAVGHAAK
CCHHHHHHHCCCCEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCHHHHHHHHHHHH
QMLGRTPGNISAIRPMKDGVIADFYVTEKMLQHFIKQVHDNSVLKPSPRVLVCVPCGSTQ
HHHCCCCCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHH
VERRAIRESALGAGAREVYLIDEPMAAAIGAGLRVSEPTGSMVVDIGGGTTEVAVISLNG
HHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCEEECCCCCEEEEECCCCEEEEEEEECC
VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAEKIKHEIGSAYPGDEVDEIEVRGRN
EEEECEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEECCCC
LAEGVPRSFSLNSNEILEALQEPLSGIVSAVMVALEQCPPELASDISENGMVLTGGGALL
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCHHH
KDLDRLLTEETGIPVVVAEEPLTCVALGGGKALEMIDMHGGDLFSEE
HHHHHHHHHCCCCCEEEECCCEEEEEECCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MFKKLRGMFSNDLSIDLGTANTLIYVKGQGIVLDEPSVVAIRQDRAGSAKSVAAVGHAAK
CCHHHHHHHCCCCEEEECCCCEEEEEECCEEEECCCCEEEEECCCCCCHHHHHHHHHHHH
QMLGRTPGNISAIRPMKDGVIADFYVTEKMLQHFIKQVHDNSVLKPSPRVLVCVPCGSTQ
HHHCCCCCCCEEECCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHH
VERRAIRESALGAGAREVYLIDEPMAAAIGAGLRVSEPTGSMVVDIGGGTTEVAVISLNG
HHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCEEECCCCCEEEEECCCCEEEEEEEECC
VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAEKIKHEIGSAYPGDEVDEIEVRGRN
EEEECEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEECCCC
LAEGVPRSFSLNSNEILEALQEPLSGIVSAVMVALEQCPPELASDISENGMVLTGGGALL
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEECCCHHH
KDLDRLLTEETGIPVVVAEEPLTCVALGGGKALEMIDMHGGDLFSEE
HHHHHHHHHCCCCCEEEECCCEEEEEECCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]