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The map label for this gene is alr

Identifier: 218708338

GI number: 218708338

Start: 279195

End: 280271

Strand: Direct

Name: alr

Synonym: VS_0285

Alternate gene names: 218708338

Gene position: 279195-280271 (Clockwise)

Preceding gene: 218708337

Following gene: 218708339

Centisome position: 8.46

GC content: 47.82

Gene sequence:

>1077_bases
ATGAAAGCAGCGACGGCGAGTATTGACTTAAACGCGCTTGAACATAACCTGAACCAGATAAAGTCGAAGGCTCCTCATTG
CAAGGTAATGTCTGTTGTGAAAGCCAATGGCTACGGTCATGGCTTACTGCATATTGCTAAGCATTCAAAAAGCTCTGATG
CTTTTGGTGTGGCGCGTATTGAAGAAGCATTACAGCTTCGTGCTGGTGGCATTGTTAAACCTATTTTGTTGCTAGAAGGG
TTTTACTCTTCGGGCGATTTGCCAATCTTGGTGACCAATAACATCCAAACGGTAGTGCATTGCGAAGAGCAATTAAGCGC
GCTAGAAAATGCAGAGTTGGAAACACCTGTTGTGGTTTGGCTAAAAGTCGACAGTGGTATGCATCGCCTAGGTGCTCGTC
CTGAGCAATACCAAAACTTTGTTGAGCGCTTACATCAATGTGCGAATGTCGCTAAACCTCTGCGCTACATGAGCCACTTC
GGTTGTGCTGATGAACTTGATAGAGCAACCACCGTTGAACAGACCGAGCTTTTCTTATCGCTCACCGACGGTTGTGAAGG
TGAGCGTTCACTTGCTGCTTCTGCGGGTCTATTAGCTTGGCCAGACAGCCACCTTGACTGGGTTCGCCCGGGAATTATCT
CTTACGGTGTTTCTCCTTTTGCTGATAAATCAGCGCAAGATCTCGGCTTTTATCCTGTAATGACTTTGACCTCGCACTTG
ATAGCGGTTCGTGATGTTAAAGCGGGTGAAAGTGTGGGTTATGGCGGTAACTGGACCAGTGAGCGAGATACCAAGGTTGG
TGTGATCGCGATAGGTTATGGTGATGGTTATCCTCGCACTGCTCCTAACGGCACTCCAGTATTCGTTAACGGCCGAAAAG
TACCGATCGCAGGACGTGTATCAATGGACATGCTAACGGTTGACCTTGGCCCTGATGCGGCAGATAAAGTCGGTGATGAA
GCAACATTATGGGGTAAAGATTTACCTTCAGAAGAAGTCGCAGAACATATCGGCACTATCGCTTACGAGCTGGTCACTAA
GCTGACTTCGCGTGTTGCGATGGAGTACGTGAAGTAG

Upstream 100 bases:

>100_bases
TCCGATCGGTTCGGTTCGTCTTACGTTCCAAGGTCAACACTCCCGATTTGATAACTATGCAGGTCCTGCATTTGATGATG
AGTAATCACTAATGACTTAC

Downstream 100 bases:

>100_bases
CTAATACGAAGTAACTAAATGTGAAGTAACTATGGATCCTATAAGTAAATGATGTTCATACGAACGACTCGACACTGGTT
AATGTCTGCAATGGCATTAC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MKAATASIDLNALEHNLNQIKSKAPHCKVMSVVKANGYGHGLLHIAKHSKSSDAFGVARIEEALQLRAGGIVKPILLLEG
FYSSGDLPILVTNNIQTVVHCEEQLSALENAELETPVVVWLKVDSGMHRLGARPEQYQNFVERLHQCANVAKPLRYMSHF
GCADELDRATTVEQTELFLSLTDGCEGERSLAASAGLLAWPDSHLDWVRPGIISYGVSPFADKSAQDLGFYPVMTLTSHL
IAVRDVKAGESVGYGGNWTSERDTKVGVIAIGYGDGYPRTAPNGTPVFVNGRKVPIAGRVSMDMLTVDLGPDAADKVGDE
ATLWGKDLPSEEVAEHIGTIAYELVTKLTSRVAMEYVK

Sequences:

>Translated_358_residues
MKAATASIDLNALEHNLNQIKSKAPHCKVMSVVKANGYGHGLLHIAKHSKSSDAFGVARIEEALQLRAGGIVKPILLLEG
FYSSGDLPILVTNNIQTVVHCEEQLSALENAELETPVVVWLKVDSGMHRLGARPEQYQNFVERLHQCANVAKPLRYMSHF
GCADELDRATTVEQTELFLSLTDGCEGERSLAASAGLLAWPDSHLDWVRPGIISYGVSPFADKSAQDLGFYPVMTLTSHL
IAVRDVKAGESVGYGGNWTSERDTKVGVIAIGYGDGYPRTAPNGTPVFVNGRKVPIAGRVSMDMLTVDLGPDAADKVGDE
ATLWGKDLPSEEVAEHIGTIAYELVTKLTSRVAMEYVK
>Mature_358_residues
MKAATASIDLNALEHNLNQIKSKAPHCKVMSVVKANGYGHGLLHIAKHSKSSDAFGVARIEEALQLRAGGIVKPILLLEG
FYSSGDLPILVTNNIQTVVHCEEQLSALENAELETPVVVWLKVDSGMHRLGARPEQYQNFVERLHQCANVAKPLRYMSHF
GCADELDRATTVEQTELFLSLTDGCEGERSLAASAGLLAWPDSHLDWVRPGIISYGVSPFADKSAQDLGFYPVMTLTSHL
IAVRDVKAGESVGYGGNWTSERDTKVGVIAIGYGDGYPRTAPNGTPVFVNGRKVPIAGRVSMDMLTVDLGPDAADKVGDE
ATLWGKDLPSEEVAEHIGTIAYELVTKLTSRVAMEYVK

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1790487, Length=358, Percent_Identity=60.3351955307263, Blast_Score=452, Evalue=1e-128,
Organism=Escherichia coli, GI1787439, Length=352, Percent_Identity=44.6022727272727, Blast_Score=293, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_VIBSL (B7VI70)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002415959.1
- GeneID:   7159936
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_0285
- HOGENOM:   HBG712172
- OMA:   EGTPVWV
- ProtClustDB:   PRK00053
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 38739; Mature: 38739

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 34-34 ACT_SITE 254-254

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAATASIDLNALEHNLNQIKSKAPHCKVMSVVKANGYGHGLLHIAKHSKSSDAFGVARI
CCCCCCEEEHHHHHHHHHHHHHCCCCCCEEHEEECCCCCCCEEEEEECCCCCCCHHHHHH
EEALQLRAGGIVKPILLLEGFYSSGDLPILVTNNIQTVVHCEEQLSALENAELETPVVVW
HHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEECCCEEEEEHHHHHHHHHCCCCCCCEEEE
LKVDSGMHRLGARPEQYQNFVERLHQCANVAKPLRYMSHFGCADELDRATTVEQTELFLS
EEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEE
LTDGCEGERSLAASAGLLAWPDSHLDWVRPGIISYGVSPFADKSAQDLGFYPVMTLTSHL
ECCCCCCCHHHHHCCCEEECCCCCCHHHCCCHHHCCCCCCCCCCCHHCCCHHHHHHHHHH
IAVRDVKAGESVGYGGNWTSERDTKVGVIAIGYGDGYPRTAPNGTPVFVNGRKVPIAGRV
HHEEECCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEECCEEECEECCC
SMDMLTVDLGPDAADKVGDEATLWGKDLPSEEVAEHIGTIAYELVTKLTSRVAMEYVK
EEEEEEEECCCCHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKAATASIDLNALEHNLNQIKSKAPHCKVMSVVKANGYGHGLLHIAKHSKSSDAFGVARI
CCCCCCEEEHHHHHHHHHHHHHCCCCCCEEHEEECCCCCCCEEEEEECCCCCCCHHHHHH
EEALQLRAGGIVKPILLLEGFYSSGDLPILVTNNIQTVVHCEEQLSALENAELETPVVVW
HHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEECCCEEEEEHHHHHHHHHCCCCCCCEEEE
LKVDSGMHRLGARPEQYQNFVERLHQCANVAKPLRYMSHFGCADELDRATTVEQTELFLS
EEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEE
LTDGCEGERSLAASAGLLAWPDSHLDWVRPGIISYGVSPFADKSAQDLGFYPVMTLTSHL
ECCCCCCCHHHHHCCCEEECCCCCCHHHCCCHHHCCCCCCCCCCCHHCCCHHHHHHHHHH
IAVRDVKAGESVGYGGNWTSERDTKVGVIAIGYGDGYPRTAPNGTPVFVNGRKVPIAGRV
HHEEECCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEECCEEECEECCC
SMDMLTVDLGPDAADKVGDEATLWGKDLPSEEVAEHIGTIAYELVTKLTSRVAMEYVK
EEEEEEEECCCCHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA