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The map label for this gene is hflC [H]

Identifier: 218708326

GI number: 218708326

Start: 265991

End: 266968

Strand: Direct

Name: hflC [H]

Synonym: VS_0273

Alternate gene names: 218708326

Gene position: 265991-266968 (Clockwise)

Preceding gene: 218708325

Following gene: 218708328

Centisome position: 8.06

GC content: 45.19

Gene sequence:

>978_bases
ATGCGTAAATTAATGATCCCTGTATTAGTTGTGACGATTGCCCTTCTATTGATGTCACTATTTGTGATTCAAGAAGGCGA
ACGTGGCATGGTAATTCGTTTTGGTCGAGTTCTCGATGACAACGGCGTATCACGAATCTATGAACCAGGCTTGCACTTTA
AACTGCCTATGTTTGATCGCGTAAAAGTACTTGATGCTCGTATTCAAACGATGGATGGTCGTTCTGACCGTTTCGTAACA
TCAGAGAAAAAAGACGTTCTAATTGATACCTACGCAAAATGGCGTATTGCTGATTTTGGACGTTTTTATCTGAGTACCGG
CGGCGGCAATATCATGACGGCAGAAGCACTTCTTGAGCGTAAAGTGACAGATGTTCTTCGTTCTGAAATTGGTTCTCGTG
AAATTAAGCAGATCGTGTCAGGCCCTCGTAATAAGGACATCCTGCCAGACTCTGCTGATAGCGAAGTTGTCACAACGGTA
GCGGCTGCAGAAGCACTAGAAGTTGATGGCGAACGCGATAAGATCATGGAAAACGTTTTGTCTGGAACGGCAGAAAGTGC
GATGGCTGATTTAGGTGTTGAAGTTGTTGATTTCCGAATGAAGAAGATTAACCTTCCTGACGAAATCAGTGAATCTATCT
ACCGCCGTATGCGTGCAGAACGTGAGTCGGTTGCTCGTAGACACCGTTCACAAGGTCGTGAGAAAGCAGAAGTTATCCGT
GCTCAAGCTGAGCTAGAAGTCGCGACTGTTCTTGCTGAAGCTGACCGTACTGCTCGAGTGACTCGTGGTGATGCTGATGC
AGAAGCAGCGAAGATCTACTCTGATGCATTTAGCAAAGACCCTGAGTTCTATGGCTTCATGCGTTCACTGCAAGCTTATG
AGACATCATTTAGCGATAAGAGCGACATTCTAGTACTGGATCCGAAGACTGACTTCTTCCAATACATGAATCAAGCAAGC
GGTGCTCCAGCAAAATAA

Upstream 100 bases:

>100_bases
CATCATCAACTTACGATCAAATTGAGTTAGAAACTCAAGCGGATCCAAAGTCTAGCACTCAAACTCGTTCAGACAGTTCA
CGTCAAGGGAGATACTAATA

Downstream 100 bases:

>100_bases
GCTGATTCGTTAATTCATTAAATTAGCGAAGTAACTGAAAATCAAAAGGCTCCCATAATGGGAGCCTTTTTGTTTTCTAT
TCGTTGAAGACTGCAGGTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MRKLMIPVLVVTIALLLMSLFVIQEGERGMVIRFGRVLDDNGVSRIYEPGLHFKLPMFDRVKVLDARIQTMDGRSDRFVT
SEKKDVLIDTYAKWRIADFGRFYLSTGGGNIMTAEALLERKVTDVLRSEIGSREIKQIVSGPRNKDILPDSADSEVVTTV
AAAEALEVDGERDKIMENVLSGTAESAMADLGVEVVDFRMKKINLPDEISESIYRRMRAERESVARRHRSQGREKAEVIR
AQAELEVATVLAEADRTARVTRGDADAEAAKIYSDAFSKDPEFYGFMRSLQAYETSFSDKSDILVLDPKTDFFQYMNQAS
GAPAK

Sequences:

>Translated_325_residues
MRKLMIPVLVVTIALLLMSLFVIQEGERGMVIRFGRVLDDNGVSRIYEPGLHFKLPMFDRVKVLDARIQTMDGRSDRFVT
SEKKDVLIDTYAKWRIADFGRFYLSTGGGNIMTAEALLERKVTDVLRSEIGSREIKQIVSGPRNKDILPDSADSEVVTTV
AAAEALEVDGERDKIMENVLSGTAESAMADLGVEVVDFRMKKINLPDEISESIYRRMRAERESVARRHRSQGREKAEVIR
AQAELEVATVLAEADRTARVTRGDADAEAAKIYSDAFSKDPEFYGFMRSLQAYETSFSDKSDILVLDPKTDFFQYMNQAS
GAPAK
>Mature_325_residues
MRKLMIPVLVVTIALLLMSLFVIQEGERGMVIRFGRVLDDNGVSRIYEPGLHFKLPMFDRVKVLDARIQTMDGRSDRFVT
SEKKDVLIDTYAKWRIADFGRFYLSTGGGNIMTAEALLERKVTDVLRSEIGSREIKQIVSGPRNKDILPDSADSEVVTTV
AAAEALEVDGERDKIMENVLSGTAESAMADLGVEVVDFRMKKINLPDEISESIYRRMRAERESVARRHRSQGREKAEVIR
AQAELEVATVLAEADRTARVTRGDADAEAAKIYSDAFSKDPEFYGFMRSLQAYETSFSDKSDILVLDPKTDFFQYMNQAS
GAPAK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=332, Percent_Identity=53.0120481927711, Blast_Score=339, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 36466; Mature: 36466

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLMIPVLVVTIALLLMSLFVIQEGERGMVIRFGRVLDDNGVSRIYEPGLHFKLPMFDR
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHCCCCCHHHHCCCCCEECCCHHH
VKVLDARIQTMDGRSDRFVTSEKKDVLIDTYAKWRIADFGRFYLSTGGGNIMTAEALLER
HHHHHHHHHHCCCCCCCEECCCCCCEEEEHHHHHHHHHCCEEEEECCCCCEEHHHHHHHH
KVTDVLRSEIGSREIKQIVSGPRNKDILPDSADSEVVTTVAAAEALEVDGERDKIMENVL
HHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
SGTAESAMADLGVEVVDFRMKKINLPDEISESIYRRMRAERESVARRHRSQGREKAEVIR
CCCHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AQAELEVATVLAEADRTARVTRGDADAEAAKIYSDAFSKDPEFYGFMRSLQAYETSFSDK
HHHHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
SDILVLDPKTDFFQYMNQASGAPAK
CCEEEECCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRKLMIPVLVVTIALLLMSLFVIQEGERGMVIRFGRVLDDNGVSRIYEPGLHFKLPMFDR
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHCCCCCHHHHCCCCCEECCCHHH
VKVLDARIQTMDGRSDRFVTSEKKDVLIDTYAKWRIADFGRFYLSTGGGNIMTAEALLER
HHHHHHHHHHCCCCCCCEECCCCCCEEEEHHHHHHHHHCCEEEEECCCCCEEHHHHHHHH
KVTDVLRSEIGSREIKQIVSGPRNKDILPDSADSEVVTTVAAAEALEVDGERDKIMENVL
HHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
SGTAESAMADLGVEVVDFRMKKINLPDEISESIYRRMRAERESVARRHRSQGREKAEVIR
CCCHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AQAELEVATVLAEADRTARVTRGDADAEAAKIYSDAFSKDPEFYGFMRSLQAYETSFSDK
HHHHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
SDILVLDPKTDFFQYMNQASGAPAK
CCEEEECCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]