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The map label for this gene is hflX [H]

Identifier: 218708324

GI number: 218708324

Start: 263451

End: 264758

Strand: Direct

Name: hflX [H]

Synonym: VS_0271

Alternate gene names: 218708324

Gene position: 263451-264758 (Clockwise)

Preceding gene: 218708323

Following gene: 218708325

Centisome position: 7.99

GC content: 45.11

Gene sequence:

>1308_bases
TTGTTTGACCGTTATGAATCCGGCGAGCGAGCCGTACTTGTTCATATCAACTTCACGCAAGAGGGAGAATGGGAAGACCT
GAGCGAATGTGAAATGCTGGTCTCCTCAGCGGGGGTAGAAACGCTACAAGTGATTACTGGTAGCCGACAATCCCCACTCC
CTAAATACTACGTTGGAGAAGGTAAAGCCCTAGAAATCGCACAAGCAGTTCAGCTAACCGGTGCTGAAATTGTGATTTTT
AACCACTCCCTCTCTCCTGCCCAAGAGCGAAACCTCGAGCAATTGTGTAAATGTCGTGTGATTGATCGCACGGGTTTGAT
CTTAGATATCTTTGCACAACGTGCGCGAACTCATGAAGGTAAGCTACAAGTTGAGCTCGCTCAGCTTCGTCATATCTCTA
CTCGATTGATTCGTGGTTGGACTCACCTTGAAAGGCAGAAAGGTGGTATTGGTCTTCGTGGTCCAGGTGAAACTCAACTG
GAAACCGATCGACGTTTGTTGCGTGACCGTATAAAGGCAATATTACGTCGTTTAGCGAAAGTCGCTAAGCAGCGTGAACA
AGGACGACGTGCTCGTAATCGAGCTGAAATCCCAACAATTTCTTTGGTTGGTTATACCAACGCGGGGAAATCAACACTTT
TCAATCGCATCACAAGTGCTGGTGTTTATGCGGCAGACCAACTGTTTGCAACCTTAGACCCAACACTACGTAAGATTGAT
TTGGCAGATGTCGGGCCTGCAATTCTCGCAGATACCGTAGGTTTTATCCGTCATCTACCACACGACTTGGTCGCTGCGTT
CAAGGCTACGTTACAAGAGACGCAGGAAGCTGACATTTTGTTACATGTTGTTGATGCCAGTGATGACCGCTTTCGTGAGA
ACATTCAGGCTGTTCATGAAGTATTAGAAGAAATCGATGCTCATGAAGTGCCAACCCTTGTAGTCATGAATAAAATTGAC
TGCATGGAAGACCAAAAACCTCGAATTGAAAGAGACGAAGAGGGCGCACCTCGCGCTGTTTGGGTTTCTGCAATGGAAGG
AGAAGGCATTGAACTGCTGTTTGAAGCTTTAACTGAGCGTTTAGCAAGTCAAATGGTTCAATTCCGATTGTGTATTCCAC
ATCAACATCAGGGCCGTATTCGTAGCTTATTCTTTGAGATGAAATGTATTCAACAAGAAGAGTATGATGAAAATGGTAAC
TTGTTGATAGATATCCGAATGCAACAAATAGATTGGTCTAAACTTGAAAAAAGAGAAGGGGCGCTCTTAGGTGGCTTTAT
CGTTACCAAAGAGACTGCTACAGTATAA

Upstream 100 bases:

>100_bases
ACAGCGGCGAGCAACAACGCGCGCCATCTGATCGTCCTGAGAAGACTGAAGATTAATCGTTCAATTGATACAGCTTGCGC
TGTAATAAGGAGTTGGTTGC

Downstream 100 bases:

>100_bases
CGTCATATCAAATGATGGAGCTTTCTAATGGCGTGGAATGAGCCTGGAAATAACAACAACGGCGATAATAACGGCCGCGA
TAACGACCCTTGGGGTAAGA

Product: putative GTPase HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MFDRYESGERAVLVHINFTQEGEWEDLSECEMLVSSAGVETLQVITGSRQSPLPKYYVGEGKALEIAQAVQLTGAEIVIF
NHSLSPAQERNLEQLCKCRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRDRIKAILRRLAKVAKQREQGRRARNRAEIPTISLVGYTNAGKSTLFNRITSAGVYAADQLFATLDPTLRKID
LADVGPAILADTVGFIRHLPHDLVAAFKATLQETQEADILLHVVDASDDRFRENIQAVHEVLEEIDAHEVPTLVVMNKID
CMEDQKPRIERDEEGAPRAVWVSAMEGEGIELLFEALTERLASQMVQFRLCIPHQHQGRIRSLFFEMKCIQQEEYDENGN
LLIDIRMQQIDWSKLEKREGALLGGFIVTKETATV

Sequences:

>Translated_435_residues
MFDRYESGERAVLVHINFTQEGEWEDLSECEMLVSSAGVETLQVITGSRQSPLPKYYVGEGKALEIAQAVQLTGAEIVIF
NHSLSPAQERNLEQLCKCRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRDRIKAILRRLAKVAKQREQGRRARNRAEIPTISLVGYTNAGKSTLFNRITSAGVYAADQLFATLDPTLRKID
LADVGPAILADTVGFIRHLPHDLVAAFKATLQETQEADILLHVVDASDDRFRENIQAVHEVLEEIDAHEVPTLVVMNKID
CMEDQKPRIERDEEGAPRAVWVSAMEGEGIELLFEALTERLASQMVQFRLCIPHQHQGRIRSLFFEMKCIQQEEYDENGN
LLIDIRMQQIDWSKLEKREGALLGGFIVTKETATV
>Mature_435_residues
MFDRYESGERAVLVHINFTQEGEWEDLSECEMLVSSAGVETLQVITGSRQSPLPKYYVGEGKALEIAQAVQLTGAEIVIF
NHSLSPAQERNLEQLCKCRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRDRIKAILRRLAKVAKQREQGRRARNRAEIPTISLVGYTNAGKSTLFNRITSAGVYAADQLFATLDPTLRKID
LADVGPAILADTVGFIRHLPHDLVAAFKATLQETQEADILLHVVDASDDRFRENIQAVHEVLEEIDAHEVPTLVVMNKID
CMEDQKPRIERDEEGAPRAVWVSAMEGEGIELLFEALTERLASQMVQFRLCIPHQHQGRIRSLFFEMKCIQQEEYDENGN
LLIDIRMQQIDWSKLEKREGALLGGFIVTKETATV

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=220, Percent_Identity=35.9090909090909, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI310133118, Length=224, Percent_Identity=35.7142857142857, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI310124269, Length=202, Percent_Identity=36.6336633663366, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI310124267, Length=202, Percent_Identity=36.6336633663366, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI310124171, Length=202, Percent_Identity=36.6336633663366, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI310124169, Length=202, Percent_Identity=36.6336633663366, Blast_Score=115, Evalue=6e-26,
Organism=Escherichia coli, GI1790615, Length=427, Percent_Identity=70.7259953161593, Blast_Score=623, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI17561038, Length=285, Percent_Identity=28.4210526315789, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24650079, Length=239, Percent_Identity=32.6359832635983, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49216; Mature: 49216

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRYESGERAVLVHINFTQEGEWEDLSECEMLVSSAGVETLQVITGSRQSPLPKYYVGE
CCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCHHEEHHHHCCCCCCCCCEECCC
GKALEIAQAVQLTGAEIVIFNHSLSPAQERNLEQLCKCRVIDRTGLILDIFAQRARTHEG
CCHHHHHHHHHHCCCEEEEEECCCCCHHHCCHHHHHHEECCCCCCHHHHHHHHHHHCCCC
KLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQLETDRRLLRDRIKAILRRLAK
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VAKQREQGRRARNRAEIPTISLVGYTNAGKSTLFNRITSAGVYAADQLFATLDPTLRKID
HHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHEEE
LADVGPAILADTVGFIRHLPHDLVAAFKATLQETQEADILLHVVDASDDRFRENIQAVHE
HHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHH
VLEEIDAHEVPTLVVMNKIDCMEDQKPRIERDEEGAPRAVWVSAMEGEGIELLFEALTER
HHHHCCCCCCCEEEEECCHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
LASQMVQFRLCIPHQHQGRIRSLFFEMKCIQQEEYDENGNLLIDIRMQQIDWSKLEKREG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHCC
ALLGGFIVTKETATV
CEEEEEEEECCCCCC
>Mature Secondary Structure
MFDRYESGERAVLVHINFTQEGEWEDLSECEMLVSSAGVETLQVITGSRQSPLPKYYVGE
CCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHCCHHEEHHHHCCCCCCCCCEECCC
GKALEIAQAVQLTGAEIVIFNHSLSPAQERNLEQLCKCRVIDRTGLILDIFAQRARTHEG
CCHHHHHHHHHHCCCEEEEEECCCCCHHHCCHHHHHHEECCCCCCHHHHHHHHHHHCCCC
KLQVELAQLRHISTRLIRGWTHLERQKGGIGLRGPGETQLETDRRLLRDRIKAILRRLAK
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VAKQREQGRRARNRAEIPTISLVGYTNAGKSTLFNRITSAGVYAADQLFATLDPTLRKID
HHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHEEE
LADVGPAILADTVGFIRHLPHDLVAAFKATLQETQEADILLHVVDASDDRFRENIQAVHE
HHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHH
VLEEIDAHEVPTLVVMNKIDCMEDQKPRIERDEEGAPRAVWVSAMEGEGIELLFEALTER
HHHHCCCCCCCEEEEECCHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
LASQMVQFRLCIPHQHQGRIRSLFFEMKCIQQEEYDENGNLLIDIRMQQIDWSKLEKREG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHCC
ALLGGFIVTKETATV
CEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]