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The map label for this gene is glnL [H]

Identifier: 218708183

GI number: 218708183

Start: 112676

End: 113752

Strand: Reverse

Name: glnL [H]

Synonym: VS_0119

Alternate gene names: 218708183

Gene position: 113752-112676 (Counterclockwise)

Preceding gene: 218708184

Following gene: 218708182

Centisome position: 3.45

GC content: 48.75

Gene sequence:

>1077_bases
GTGAATCGATCAGCCAAAAGCGACAGCATAGATACACATCATCTTTCCAGCGCCATTCTCGACAATATGGTGACCTCAAC
ATTGATGCTCGATGAGCAACTGTATGTCCGATATGCCAACCCGGCGGCTGAACAACTCTTTTCGCAAAGTGCACGACGTA
TCGTTGATCACCCTCTGAGCCAACTTATCCAGCACGCCTCACTGGATTTAGCGCTGTTGACTCAACCGCTACAAAGTGGC
CAAAGCATTACCGACAGTGACGTTACTTTTGTGGTTGATAACCGCCCACTAATGCTTGAGGTAACAGTGAGCCCAATCTC
TTGGCAGCGAGAAACGCTGTTATTGGTTGAGATGCGCAAGATAGACCAACAAAGACGCCTCAGCCAAGAGCTCAACCAAC
ACGCTCAACAACAAGCGGCTAAACTATTGGTACGCGGATTAGCCCATGAGATTAAGAATCCATTGGGCGGATTAAGAGGA
GCCGCGCAGCTACTTGGTAAAATGCTCCCTGATCAGTCCCTTAATGAATATACGCAGATCATTATTGAACAAGCCGACCG
CCTGAGAGCTTTGGTCGATCGCCTGCTTGGCCCACAGAAACCGGGGACCAAATCGGAAGAGAACCTTCACCAAATACTTG
AAAAAGTAAGGCAACTCGTCGAGCTAGAATCAGGTTCAACACTCGTCATCGAACGAGACTACGACCCGAGCCTACCGGAC
ATCTTGATGGATTCAGCACAGGTAGAACAAGCCATGCTCAATATAGTGAGCAACGCAGCTCAGATTCTGAAGGCTCAAGA
ATCAGGAAAAATCACCATTCGCACCAGAACGGTGCATCAAGCAAACATTCATGGTCAGCGACACAAACTCGCCGCTCGCA
TTGAGATCTGCGACAACGGCCCGGGTATCCCCGATGAATTGAAAGACACCCTGTTTTACCCAATGGTCAGCGGACGAGAA
GGAGGTACAGGGCTAGGGCTATCGATATCTCAAAACCTGATCGATCAACACAATGGGAAAATTGATGTTGAAAGCTGGCC
GGGCAACACCACATTCACGATTTATTTGCCGATATAA

Upstream 100 bases:

>100_bases
AATGAATTATCTTTAGCTTCTGGTTGATATGCGCCATACTTGAACTTAGCTTCGCACCAATTTGGTGCAGTGAGAAAAAC
ACCAGTTCAAGGACGAAATA

Downstream 100 bases:

>100_bases
GCAAAGCTGTGTCTCCCACTGGAAACAACGTTTCACTGGCAACACTGAATACCGAACAATAAAAACAACAATGATTATCA
CAATAGATTTGGCTGCAAAG

Product: nitrogen regulation protein NR(II)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MNRSAKSDSIDTHHLSSAILDNMVTSTLMLDEQLYVRYANPAAEQLFSQSARRIVDHPLSQLIQHASLDLALLTQPLQSG
QSITDSDVTFVVDNRPLMLEVTVSPISWQRETLLLVEMRKIDQQRRLSQELNQHAQQQAAKLLVRGLAHEIKNPLGGLRG
AAQLLGKMLPDQSLNEYTQIIIEQADRLRALVDRLLGPQKPGTKSEENLHQILEKVRQLVELESGSTLVIERDYDPSLPD
ILMDSAQVEQAMLNIVSNAAQILKAQESGKITIRTRTVHQANIHGQRHKLAARIEICDNGPGIPDELKDTLFYPMVSGRE
GGTGLGLSISQNLIDQHNGKIDVESWPGNTTFTIYLPI

Sequences:

>Translated_358_residues
MNRSAKSDSIDTHHLSSAILDNMVTSTLMLDEQLYVRYANPAAEQLFSQSARRIVDHPLSQLIQHASLDLALLTQPLQSG
QSITDSDVTFVVDNRPLMLEVTVSPISWQRETLLLVEMRKIDQQRRLSQELNQHAQQQAAKLLVRGLAHEIKNPLGGLRG
AAQLLGKMLPDQSLNEYTQIIIEQADRLRALVDRLLGPQKPGTKSEENLHQILEKVRQLVELESGSTLVIERDYDPSLPD
ILMDSAQVEQAMLNIVSNAAQILKAQESGKITIRTRTVHQANIHGQRHKLAARIEICDNGPGIPDELKDTLFYPMVSGRE
GGTGLGLSISQNLIDQHNGKIDVESWPGNTTFTIYLPI
>Mature_358_residues
MNRSAKSDSIDTHHLSSAILDNMVTSTLMLDEQLYVRYANPAAEQLFSQSARRIVDHPLSQLIQHASLDLALLTQPLQSG
QSITDSDVTFVVDNRPLMLEVTVSPISWQRETLLLVEMRKIDQQRRLSQELNQHAQQQAAKLLVRGLAHEIKNPLGGLRG
AAQLLGKMLPDQSLNEYTQIIIEQADRLRALVDRLLGPQKPGTKSEENLHQILEKVRQLVELESGSTLVIERDYDPSLPD
ILMDSAQVEQAMLNIVSNAAQILKAQESGKITIRTRTVHQANIHGQRHKLAARIEICDNGPGIPDELKDTLFYPMVSGRE
GGTGLGLSISQNLIDQHNGKIDVESWPGNTTFTIYLPI

Specific function: NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC. In nitrogen limitation ntrB activates ntrC by phosphorylating it, while in nitrogen excess ntrC is dephosphorylated and consequently inactiva

COG id: COG3852

COG function: function code T; Signal transduction histidine kinase, nitrogen specific

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790300, Length=340, Percent_Identity=58.2352941176471, Blast_Score=402, Evalue=1e-113,
Organism=Escherichia coli, GI1788549, Length=354, Percent_Identity=29.0960451977401, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1790436, Length=259, Percent_Identity=30.1158301158301, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1789808, Length=222, Percent_Identity=26.5765765765766, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081816, Length=256, Percent_Identity=28.90625, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1789149, Length=269, Percent_Identity=27.8810408921933, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI48994928, Length=252, Percent_Identity=25, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=27.8969957081545, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790861, Length=245, Percent_Identity=26.530612244898, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 39868; Mature: 39868

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRSAKSDSIDTHHLSSAILDNMVTSTLMLDEQLYVRYANPAAEQLFSQSARRIVDHPLS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHEEECCHHHHHHHHHHHHHHHHHHHH
QLIQHASLDLALLTQPLQSGQSITDSDVTFVVDNRPLMLEVTVSPISWQRETLLLVEMRK
HHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHH
IDQQRRLSQELNQHAQQQAAKLLVRGLAHEIKNPLGGLRGAAQLLGKMLPDQSLNEYTQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IIEQADRLRALVDRLLGPQKPGTKSEENLHQILEKVRQLVELESGSTLVIERDYDPSLPD
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHH
ILMDSAQVEQAMLNIVSNAAQILKAQESGKITIRTRTVHQANIHGQRHKLAARIEICDNG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHHHEEEEEEECCC
PGIPDELKDTLFYPMVSGREGGTGLGLSISQNLIDQHNGKIDVESWPGNTTFTIYLPI
CCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEEEEECC
>Mature Secondary Structure
MNRSAKSDSIDTHHLSSAILDNMVTSTLMLDEQLYVRYANPAAEQLFSQSARRIVDHPLS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHEEECCHHHHHHHHHHHHHHHHHHHH
QLIQHASLDLALLTQPLQSGQSITDSDVTFVVDNRPLMLEVTVSPISWQRETLLLVEMRK
HHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHH
IDQQRRLSQELNQHAQQQAAKLLVRGLAHEIKNPLGGLRGAAQLLGKMLPDQSLNEYTQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IIEQADRLRALVDRLLGPQKPGTKSEENLHQILEKVRQLVELESGSTLVIERDYDPSLPD
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHH
ILMDSAQVEQAMLNIVSNAAQILKAQESGKITIRTRTVHQANIHGQRHKLAARIEICDNG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCHHHHHEEEEEEECCC
PGIPDELKDTLFYPMVSGREGGTGLGLSISQNLIDQHNGKIDVESWPGNTTFTIYLPI
CCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2574025 [H]