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The map label for this gene is avtA [H]

Identifier: 218708103

GI number: 218708103

Start: 14772

End: 16025

Strand: Reverse

Name: avtA [H]

Synonym: VS_0015

Alternate gene names: 218708103

Gene position: 16025-14772 (Counterclockwise)

Preceding gene: 218708118

Following gene: 218708097

Centisome position: 0.49

GC content: 47.13

Gene sequence:

>1254_bases
ATGCAATTCTCAAAGTTTGGTGAAAAGTTTAATCGATACTCTGGAATCACTCGTTTAATGGATGATTTGAATGATGGCCT
GCGAACTCCTGGTGCAATTATGCTCGGTGGTGGTAACCCAGCCGCTATCCCAGCCATGCTCGATTACTTTAACCAAGCCA
GTGCCGACATGCTCGCCAGTGGAGAACTCATTGCCGCCCTCGCCAACTACGATGGTCCGCAAGGCAAAGACAGCTTCATT
AAATCATTAGCGGCGATGCTAAAAGAGACTTATGGCTGGGACATCAGCGAGAAGAACATCAGCCTGACTAATGGCAGTCA
GAGCGGCTTCTTTTACCTATTCAACCTGTTAGCGGGTCAACAGCCAGACGGTTCTCACAAGAAGATATTGTTGCCGATCG
CACCAGAATACATCGGCTACGGCGATGCGGGCATTGATGACGATATTTTTATCTCTTACCACCCAGAGATCGAACTGCTA
GAAAACCGCCAGTTTAAATACCACGTTGATTTTGAACAGCTCAAGGTTGATGACTCGGTTGCCGCTATCTGCGCCTCTCG
TCCAACCAACCCAACTGGTAACGTACTGACCGATGAAGAAGTGCGTAAACTGGATAAGCTGGCGCGTGAAAACAACATCC
CACTGCTGATCGACAATGCTTACGGCCTGCCGTTTCCAAACATCATCTTTGAAGATGTCGAACCGTTCTGGAATGAAAAC
ACCATTCTGTGCATGAGCTTATCTAAGCTTGGTTTGCCGGGTGTACGTTGCGGTATCGTGATTGCGAGCGAAGAAGTGAC
ACAAGCTCTGACCAACATGAATGGCATTATCAGCCTAGCACCCAATAGTGTCGGCCCTGCAATTGCCAATCACATGATTG
AAAAAGGCGATTTACTGCGCTTGAGCAGTGAGGTAATAAAACCTTTCTATAAAGACAAATCTCTACGTGCGGTTGAGCTT
TTACAAGAAGCGATCGATGACCCTCGTTTCCGTATCCACAAACCTGAAGGTGCGATTTTCTTGTGGCTATGGTTTGATGA
GCTGCCGATTACCACCATGGAGCTGTACGACCGCCTTAAAGCTCGTGGCGTATTGATTGTTCCGGGTGAATACTTCTTTA
TCGGTCAAGAAGACGAGTGGGATCATGCTCACCAGTGCTTACGCATGAACTACGTACAAGATGATGAGGCGATGCAGAAA
GGTATTGCTATCATTGCTGAAGAAGTGAAAAAGGCTTACAGCGAAAGCAAATAA

Upstream 100 bases:

>100_bases
GTATGTTCAAAGATTACCCACTGTAACCCGCCACGCTCGGGTTCATAAGATTGATCATAATCTACGAATAATAATCACAA
TGAATTAGGTATACGAAGCA

Downstream 100 bases:

>100_bases
ATATTCCCTACTCGGTCGTTCCGCTATGGAATGGACGATGATAGGACAAACAAAAAAGAGCACCTACCTTTTTCAAGGTA
CTGGTGCTCTTTCACTTTTA

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MQFSKFGEKFNRYSGITRLMDDLNDGLRTPGAIMLGGGNPAAIPAMLDYFNQASADMLASGELIAALANYDGPQGKDSFI
KSLAAMLKETYGWDISEKNISLTNGSQSGFFYLFNLLAGQQPDGSHKKILLPIAPEYIGYGDAGIDDDIFISYHPEIELL
ENRQFKYHVDFEQLKVDDSVAAICASRPTNPTGNVLTDEEVRKLDKLARENNIPLLIDNAYGLPFPNIIFEDVEPFWNEN
TILCMSLSKLGLPGVRCGIVIASEEVTQALTNMNGIISLAPNSVGPAIANHMIEKGDLLRLSSEVIKPFYKDKSLRAVEL
LQEAIDDPRFRIHKPEGAIFLWLWFDELPITTMELYDRLKARGVLIVPGEYFFIGQEDEWDHAHQCLRMNYVQDDEAMQK
GIAIIAEEVKKAYSESK

Sequences:

>Translated_417_residues
MQFSKFGEKFNRYSGITRLMDDLNDGLRTPGAIMLGGGNPAAIPAMLDYFNQASADMLASGELIAALANYDGPQGKDSFI
KSLAAMLKETYGWDISEKNISLTNGSQSGFFYLFNLLAGQQPDGSHKKILLPIAPEYIGYGDAGIDDDIFISYHPEIELL
ENRQFKYHVDFEQLKVDDSVAAICASRPTNPTGNVLTDEEVRKLDKLARENNIPLLIDNAYGLPFPNIIFEDVEPFWNEN
TILCMSLSKLGLPGVRCGIVIASEEVTQALTNMNGIISLAPNSVGPAIANHMIEKGDLLRLSSEVIKPFYKDKSLRAVEL
LQEAIDDPRFRIHKPEGAIFLWLWFDELPITTMELYDRLKARGVLIVPGEYFFIGQEDEWDHAHQCLRMNYVQDDEAMQK
GIAIIAEEVKKAYSESK
>Mature_417_residues
MQFSKFGEKFNRYSGITRLMDDLNDGLRTPGAIMLGGGNPAAIPAMLDYFNQASADMLASGELIAALANYDGPQGKDSFI
KSLAAMLKETYGWDISEKNISLTNGSQSGFFYLFNLLAGQQPDGSHKKILLPIAPEYIGYGDAGIDDDIFISYHPEIELL
ENRQFKYHVDFEQLKVDDSVAAICASRPTNPTGNVLTDEEVRKLDKLARENNIPLLIDNAYGLPFPNIIFEDVEPFWNEN
TILCMSLSKLGLPGVRCGIVIASEEVTQALTNMNGIISLAPNSVGPAIANHMIEKGDLLRLSSEVIKPFYKDKSLRAVEL
LQEAIDDPRFRIHKPEGAIFLWLWFDELPITTMELYDRLKARGVLIVPGEYFFIGQEDEWDHAHQCLRMNYVQDDEAMQK
GIAIIAEEVKKAYSESK

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=416, Percent_Identity=62.2596153846154, Blast_Score=561, Evalue=1e-161,
Organism=Saccharomyces cerevisiae, GI6322401, Length=367, Percent_Identity=20.4359673024523, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 46602; Mature: 46602

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFSKFGEKFNRYSGITRLMDDLNDGLRTPGAIMLGGGNPAAIPAMLDYFNQASADMLAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCHHHHHC
GELIAALANYDGPQGKDSFIKSLAAMLKETYGWDISEKNISLTNGSQSGFFYLFNLLAGQ
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCC
QPDGSHKKILLPIAPEYIGYGDAGIDDDIFISYHPEIELLENRQFKYHVDFEQLKVDDSV
CCCCCCCEEEEEECHHHCCCCCCCCCCCEEEEECCCEEEECCCCEEEEECHHHHCCCHHH
AAICASRPTNPTGNVLTDEEVRKLDKLARENNIPLLIDNAYGLPFPNIIFEDVEPFWNEN
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHCCCHHHCCC
TILCMSLSKLGLPGVRCGIVIASEEVTQALTNMNGIISLAPNSVGPAIANHMIEKGDLLR
EEEEEEHHHCCCCCCEEEEEEECHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCHHH
LSSEVIKPFYKDKSLRAVELLQEAIDDPRFRIHKPEGAIFLWLWFDELPITTMELYDRLK
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHH
ARGVLIVPGEYFFIGQEDEWDHAHQCLRMNYVQDDEAMQKGIAIIAEEVKKAYSESK
HCEEEEECCCEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQFSKFGEKFNRYSGITRLMDDLNDGLRTPGAIMLGGGNPAAIPAMLDYFNQASADMLAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHCCHHHHHC
GELIAALANYDGPQGKDSFIKSLAAMLKETYGWDISEKNISLTNGSQSGFFYLFNLLAGQ
CHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCC
QPDGSHKKILLPIAPEYIGYGDAGIDDDIFISYHPEIELLENRQFKYHVDFEQLKVDDSV
CCCCCCCEEEEEECHHHCCCCCCCCCCCEEEEECCCEEEECCCCEEEEECHHHHCCCHHH
AAICASRPTNPTGNVLTDEEVRKLDKLARENNIPLLIDNAYGLPFPNIIFEDVEPFWNEN
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHCCCHHHCCC
TILCMSLSKLGLPGVRCGIVIASEEVTQALTNMNGIISLAPNSVGPAIANHMIEKGDLLR
EEEEEEHHHCCCCCCEEEEEEECHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCHHH
LSSEVIKPFYKDKSLRAVELLQEAIDDPRFRIHKPEGAIFLWLWFDELPITTMELYDRLK
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCCCCHHHHHHHHHH
ARGVLIVPGEYFFIGQEDEWDHAHQCLRMNYVQDDEAMQKGIAIIAEEVKKAYSESK
HCEEEEECCCEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]