Click here to switch to the map view.

The map label for this gene is fliC [H]

Identifier: 218705418

GI number: 218705418

Start: 2235544

End: 2237208

Strand: Reverse

Name: fliC [H]

Synonym: ECUMN_2215

Alternate gene names: 218705418

Gene position: 2237208-2235544 (Counterclockwise)

Preceding gene: 218705423

Following gene: 218705417

Centisome position: 43.01

GC content: 46.19

Gene sequence:

>1665_bases
ATGGCACAAGTCATTAATACCAACAGCCTCTCGCTGATCACTCAAAATAATATCAACAAGAACCAGTCTGCGCTGTCGAG
TTCTATCGAGCGTCTGTCTTCTGGCTTGCGTATTAACAGCGCGAAGGATGACGCCGCAGGTCAGGCGATTGCTAACCGTT
TTACTTCTAATATTAAAGGCCTGACTCAGGCTGCACGTAACGCCAATGACGGTATTTCTGTTGCACAGACCACTGAAGGC
GCGCTGTCCGAAATCAACAACAACTTACAGCGTATTCGTGAACTGACGGTTCAGGCCACTACAGGGACTAACTCCGATTC
TGACCTGGACTCCATCCAGGACGAAATCAAATCTCGTCTGGACGAAATTGACCGCGTATCCGGTCAGACCCAGTTCAACG
GCGTGAACGTGCTGTCCAAAGATGGTTCAATGAAAATTCAGGTCGGCGCAAATGATGGTGAAACCATCACGATTGATCTG
AAGAAAATTGACTCTGATACGCTGAATCTGGCTGGTTTTAACGTGAATGGCGAAGGTGAAACAGCCAATACTGCTGCAAC
ACTTAAAGATATGGTTGGTTTAAAACTCGATAATACGGGGGTCACTACAGCTGGAGTTAATAGATATATTGCTGACAAAG
CCGTCGCAAGTAGCACGGATATTTTGAATGCGGTAGCTGGTGTTGATGGCAGTAAAGTTTCCACGGAGGCAGATGTTGGT
TTTGGTGCAGCTGCCCCTGGTACGCCAGTGGAATATACTTATCATAAAGATACTAACACATATACGGCTTCTGCTTCAGT
TGATGCGACTCAACTGGCGGCATTCCTGAATCCTGAAGCGGGTGGTACCACTGCTGCAACAGTAAGTATTGGCAACGGTA
CAACAGCTCAAGAGCAAAAAGTCATTATTGCTAAAGATGGTTCTTTAACTGCTGCTGATGACGGTGCCGCTCTCTATCTT
GATGATACTGGTAACTTAAGTAAAACTAACGCAGGCACTGATACTCAAGCTAAACTGTCTGACTTAATGGCAAACAATGC
TAATGCCAAAACAGTCATTACAACAGATAAAGGTACATTTACTGCTAATACGACAAAGTTTGATGGGGTAGATATTTCTG
TTGATGCTTCAACGTTTGCTAACGCCGTTAAAAATGAGACTTACACTGCAACTGTTGGTGTAACTTTACCTGCGACATAT
ACAGTCAATAATGGCACTGCTGCATCAGCGTATTTAGTCGATGGAAAAGTGAGCAAAACTCCTGCCGAGTATTTTGCTCA
AGCTGATGGCACTATTACTAGTGGTGAAAATGCGGCTACCAGTAAAGCTATCTATGTAAGTGCCAATGGTAACTTAACGA
CTAATACAACTAGTGAATCTGAAGCTACTACCAACCCGCTGGCAGCATTGGATGACGCTATCGCGTCTATCGACAAATTC
CGTTCTTCCCTGGGTGCTATCCAGAACCGTCTGGATTCCGCAGTCACCAACCTGAACAACACCACTACCAACCTGTCTGA
AGCGCAGTCCCGTATTCAGGACGCCGACTATGCGACCGAAGTGTCCAACATGTCGAAAGCGCAGATCATTCAGCAGGCCG
GTAACTCCGTGCTGGCAAAAGCCAACCAGGTACCGCAGCAGGTTCTGTCTCTGCTGCAGGGTTAA

Upstream 100 bases:

>100_bases
AGGTTGTTTTACGACAGACGATAACAGGGTTGACGGCGATTGAGCCGACGGGTGGAAACCCAATACGTAATCAACGACTT
GCAATATAGGATAACGAATC

Downstream 100 bases:

>100_bases
TCGTCCTAACCTGATTAACTGAGACTGACGGCAACGCCAAATTGCCTGATGCGCTGCGCTTATCAGGCCTACAAGGTGAA
TTGCAATTTATTGAATTTGC

Product: flagellin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MAQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQAARNANDGISVAQTTEG
ALSEINNNLQRIRELTVQATTGTNSDSDLDSIQDEIKSRLDEIDRVSGQTQFNGVNVLSKDGSMKIQVGANDGETITIDL
KKIDSDTLNLAGFNVNGEGETANTAATLKDMVGLKLDNTGVTTAGVNRYIADKAVASSTDILNAVAGVDGSKVSTEADVG
FGAAAPGTPVEYTYHKDTNTYTASASVDATQLAAFLNPEAGGTTAATVSIGNGTTAQEQKVIIAKDGSLTAADDGAALYL
DDTGNLSKTNAGTDTQAKLSDLMANNANAKTVITTDKGTFTANTTKFDGVDISVDASTFANAVKNETYTATVGVTLPATY
TVNNGTAASAYLVDGKVSKTPAEYFAQADGTITSGENAATSKAIYVSANGNLTTNTTSESEATTNPLAALDDAIASIDKF
RSSLGAIQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLAKANQVPQQVLSLLQG

Sequences:

>Translated_554_residues
MAQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQAARNANDGISVAQTTEG
ALSEINNNLQRIRELTVQATTGTNSDSDLDSIQDEIKSRLDEIDRVSGQTQFNGVNVLSKDGSMKIQVGANDGETITIDL
KKIDSDTLNLAGFNVNGEGETANTAATLKDMVGLKLDNTGVTTAGVNRYIADKAVASSTDILNAVAGVDGSKVSTEADVG
FGAAAPGTPVEYTYHKDTNTYTASASVDATQLAAFLNPEAGGTTAATVSIGNGTTAQEQKVIIAKDGSLTAADDGAALYL
DDTGNLSKTNAGTDTQAKLSDLMANNANAKTVITTDKGTFTANTTKFDGVDISVDASTFANAVKNETYTATVGVTLPATY
TVNNGTAASAYLVDGKVSKTPAEYFAQADGTITSGENAATSKAIYVSANGNLTTNTTSESEATTNPLAALDDAIASIDKF
RSSLGAIQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLAKANQVPQQVLSLLQG
>Mature_553_residues
AQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQAARNANDGISVAQTTEGA
LSEINNNLQRIRELTVQATTGTNSDSDLDSIQDEIKSRLDEIDRVSGQTQFNGVNVLSKDGSMKIQVGANDGETITIDLK
KIDSDTLNLAGFNVNGEGETANTAATLKDMVGLKLDNTGVTTAGVNRYIADKAVASSTDILNAVAGVDGSKVSTEADVGF
GAAAPGTPVEYTYHKDTNTYTASASVDATQLAAFLNPEAGGTTAATVSIGNGTTAQEQKVIIAKDGSLTAADDGAALYLD
DTGNLSKTNAGTDTQAKLSDLMANNANAKTVITTDKGTFTANTTKFDGVDISVDASTFANAVKNETYTATVGVTLPATYT
VNNGTAASAYLVDGKVSKTPAEYFAQADGTITSGENAATSKAIYVSANGNLTTNTTSESEATTNPLAALDDAIASIDKFR
SSLGAIQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLAKANQVPQQVLSLLQG

Specific function: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella [H]

COG id: COG1344

COG function: function code N; Flagellin and related hook-associated proteins

Gene ontology:

Cell location: Secreted. Bacterial flagellum [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial flagellin family [H]

Homologues:

Organism=Escherichia coli, GI1788232, Length=560, Percent_Identity=55.3571428571429, Blast_Score=454, Evalue=1e-129,

Paralogues:

None

Copy number: 200,000-400,000 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001492
- InterPro:   IPR001029 [H]

Pfam domain/function: PF00700 Flagellin_C; PF00669 Flagellin_N [H]

EC number: NA

Molecular weight: Translated: 57244; Mature: 57113

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKG
CCEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHH
LTQAARNANDGISVAQTTEGALSEINNNLQRIRELTVQATTGTNSDSDLDSIQDEIKSRL
HHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHH
DEIDRVSGQTQFNGVNVLSKDGSMKIQVGANDGETITIDLKKIDSDTLNLAGFNVNGEGE
HHHHHHCCCCEECCEEEEECCCCEEEEEECCCCCEEEEEEEECCCCEEEEEEEEECCCCC
TANTAATLKDMVGLKLDNTGVTTAGVNRYIADKAVASSTDILNAVAGVDGSKVSTEADVG
CCHHHHHHHHHHCEEECCCCCCHHCCHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCC
FGAAAPGTPVEYTYHKDTNTYTASASVDATQLAAFLNPEAGGTTAATVSIGNGTTAQEQK
CCCCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCE
VIIAKDGSLTAADDGAALYLDDTGNLSKTNAGTDTQAKLSDLMANNANAKTVITTDKGTF
EEEEECCCEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCEE
TANTTKFDGVDISVDASTFANAVKNETYTATVGVTLPATYTVNNGTAASAYLVDGKVSKT
EECCEEECCEEEEECHHHHHHHHCCCEEEEEEEEEECEEEEECCCCEEEEEEECCCCCCC
PAEYFAQADGTITSGENAATSKAIYVSANGNLTTNTTSESEATTNPLAALDDAIASIDKF
HHHHHHHCCCCEECCCCCCCCEEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHH
RSSLGAIQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLAK
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHCCHHHHHHHHCCCHHHHH
ANQVPQQVLSLLQG
HHHHHHHHHHHHCC
>Mature Secondary Structure 
AQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKG
CEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHH
LTQAARNANDGISVAQTTEGALSEINNNLQRIRELTVQATTGTNSDSDLDSIQDEIKSRL
HHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHH
DEIDRVSGQTQFNGVNVLSKDGSMKIQVGANDGETITIDLKKIDSDTLNLAGFNVNGEGE
HHHHHHCCCCEECCEEEEECCCCEEEEEECCCCCEEEEEEEECCCCEEEEEEEEECCCCC
TANTAATLKDMVGLKLDNTGVTTAGVNRYIADKAVASSTDILNAVAGVDGSKVSTEADVG
CCHHHHHHHHHHCEEECCCCCCHHCCHHHHHHHHHHCHHHHHHHHHCCCCCCCCCCCCCC
FGAAAPGTPVEYTYHKDTNTYTASASVDATQLAAFLNPEAGGTTAATVSIGNGTTAQEQK
CCCCCCCCCEEEEEECCCCEEEEECCCCHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCE
VIIAKDGSLTAADDGAALYLDDTGNLSKTNAGTDTQAKLSDLMANNANAKTVITTDKGTF
EEEEECCCEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCEE
TANTTKFDGVDISVDASTFANAVKNETYTATVGVTLPATYTVNNGTAASAYLVDGKVSKT
EECCEEECCEEEEECHHHHHHHHCCCEEEEEEEEEECEEEEECCCCEEEEEEECCCCCCC
PAEYFAQADGTITSGENAATSKAIYVSANGNLTTNTTSESEATTNPLAALDDAIASIDKF
HHHHHHHCCCCEECCCCCCCCEEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHH
RSSLGAIQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLAK
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHCCHHHHHHHHCCCHHHHH
ANQVPQQVLSLLQG
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8057852; 12384590; 12704152 [H]