Click here to switch to the map view.

The map label for this gene is torZ [H]

Identifier: 218705373

GI number: 218705373

Start: 2189521

End: 2191950

Strand: Reverse

Name: torZ [H]

Synonym: ECUMN_2170

Alternate gene names: 218705373

Gene position: 2191950-2189521 (Counterclockwise)

Preceding gene: 218705374

Following gene: 218705367

Centisome position: 42.14

GC content: 51.69

Gene sequence:

>2430_bases
ATGACATTAACAAGACGTGAATTTATTAAACACAGCGGTATTGCCGCTGGGGCGCTGGTGGTGACATCGGCTGCACCGCT
ACCCGCATGGGCAGAAGAGAAGGGCGGTAAAATCCTCACCGCGGGACGTTGGGGAGCGATGAACGTAGAAGTGAAGGACG
GCAAGATTGTTTCTTCGACAGGCGCGCTGGCGAAAACCATACCGAACTCCTTACAGTCTACGGCGGCGGATCAGGTACAC
ACCACGGCGCGTATTCAGCATCCGATGGTGAGAAAAAGCTATCTCGATAATCCACTGCAACCGGCAAAAGGTCGTGGCGA
AGATACCTATGTACAGGTGAGCTGGGAACAAGCATTAAAACTGATTCATGAGCAACACGATCGTATTCGTAAAGCTAACG
GACCATCGGCCATTTTTGCCGGATCTTACGGCTGGCGATCTTCTGGCGTGTTGCATAAAGCGCAAACCTTACTGCAACGT
TATATGAACCTTGCGGGCGGTTATTCCGGGCATAGCGGCGATTATTCAACCGGGGCGGCACAGGTGATCATGCCGCATGT
GGTCGGTTCTGTAGAGGTGTATGAACAGCAGACCTCCTGGCCGCTGATTCTGGAAAACAGCCAGGTTGTGGTGCTGTGGG
GGATGAACCCGCTGAATACCTTAAAAATTGCCTGGAGCAGTACCGATGAGCAAGGGCTGGAATACTTCCATCAGCTGAAA
AAATCTGGCAAACCCGTGATTGCCATTGATCCTATCCGCTCCGAAACCATCGAATTCTTTGGCGATAATGCCACCTGGAT
CGCGCCGAATATGGGCACCGACGTGGCACTGATGTTAGGGATTGCGCATACCCTGATGACACAAGGCAAACACGATAAAG
TGTTCCTTGAAAAATACACTACCGGATATCCGCAGTTTGAAGAGTATCTGACAGGTAAGAGCGATAATACACCGAAGAGC
GCGGCCTGGGCGGCGGAAATTTCTGGCGTACCGGAAGCGCAGATAGTCAAACTCGCTGAACTGATGGCGGCGAATCGCAC
AATGCTGATGGCAGGCTGGGGAATTCAGCGCCAGCAATATGGTGAACAGAAACACTGGATGCTGGTGACGCTGGCGGCGA
TGTTAGGGCAGATTGGTACACCGGGCGGCGGTTTTGGTTTCTCTTATCATTACTCCAATGGTGGCAACCCGACGCGTGTT
GGCGGCGTGCTGCCGGAAATGTCTGCGGCGATTGCCGGACAGGCCAGCGAGGCCGCTGATGATGGCGGAATGACGGCGAT
TCCTGTTGCCCGTATCGTCGATGCGCTGGAAAATCCTGGCGGCAAATATCAGCATAACGGTAAAGAACAAACGTATCCGA
ATATCAAAATGATCTGGTGGGCGGGTGGCGGGAACTTTACCCATCACCAGGATACTAATCGTCTGATTAAAGCATGGCAG
AAACCGGAGATGATCGTCGTTTCTGAATGCTACTGGACCGCAGCTGCTAAACATGCAGATATCGTATTACCGATCACCAC
ATCGTTTGAGCGCAATGACTTGACGATGACCGGTGATTACAGCAACCAGCATATTGTACCGATGAAGCAGGCTGTCGCTG
CGCAATTTGAAGCGCGTAACGATTTTGACGTGTTTGCCGATCTTGCTGAATTACTGAAACCTGGCGGAAAAGAGATCTAT
ACCGAAGGTAAAGATGAGATGGCGTGGCTGAAATTTTTCTATGATGCCGCTCAGAAAGGTGCCCGTGCGCAACGCGTGAC
TATGCCGATGTTTAATGCCTTCTGGCAGCAAAATAAACTGATCGAAATGCGCCGCAGCGAGAAGAACGAACAGTACGTTC
GTTATGGTGATTTCCGCGCCGATCCGGTGAAAAATGCGCTGGGTACGCCAAGCGGCAAAATTGAGATTTACTCCAAAACG
CTGGAAAAATTTGGCTATAAGGATTGCCCGGCACACCCAACCTGGCTTGCGCCTGATGAGTGGAAGGGTACCGCCGACGA
GAAGCAGTTGCAGCTTCTGACCGCACATCCGGCACATCGTTTACACAGTCAGCTTAACTATGCGGAACTGCGTAAAAAAT
ATGCGGTTGCCGATCGTGAACCGATCACTATTCACACCGAAGATGCTGCTCGCTTTGGTATTGCGAATGGCGATCTGGTG
CGTGTCTGGAACAAACGTGGTCAGATTCTGACAGGCGCGGTGGTGACTGACGGGATCAAAAAAGGCGTGGTATGCGTGCA
TGAAGGTGCATGGCCAGATCTGGAAAATGGCTTGTGTAAAAACGGCAGTGCGAACGTGTTAACGGCGGATATCCCCAGCT
CTCAGCTGGCAAATGCCTGTGCCGGTAACTCTGCGCTGGTGTATATCGAAAAATATACGAGCAATGCGCCGAAGTTAACG
GCGTTTGATCAGCCAGCTGTTCAGGCATAA

Upstream 100 bases:

>100_bases
CATGAGCGAAAATGAACTGGACATTTTGACGCGGTACTTCCAGTACAACGCCAAAGATATTAGCGAAAAACAGTGATCCT
CGTTGATCAGGGAGGAAGTT

Downstream 100 bases:

>100_bases
GACGTGAAAAGCGCCCGGAAACGGGCGCTAATCTTTACGGCTTACGCGCAATCAGCACCGCGCGTTTAGGCGCAGGATAA
CCTTCCACCGTTTTACCCGG

Product: trimethylamine N-oxide reductase system III, catalytic subunit

Products: NA

Alternate protein names: TMAO reductase 2; Trimethylamine oxidase 2 [H]

Number of amino acids: Translated: 809; Mature: 808

Protein sequence:

>809_residues
MTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRWGAMNVEVKDGKIVSSTGALAKTIPNSLQSTAADQVH
TTARIQHPMVRKSYLDNPLQPAKGRGEDTYVQVSWEQALKLIHEQHDRIRKANGPSAIFAGSYGWRSSGVLHKAQTLLQR
YMNLAGGYSGHSGDYSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPLNTLKIAWSSTDEQGLEYFHQLK
KSGKPVIAIDPIRSETIEFFGDNATWIAPNMGTDVALMLGIAHTLMTQGKHDKVFLEKYTTGYPQFEEYLTGKSDNTPKS
AAWAAEISGVPEAQIVKLAELMAANRTMLMAGWGIQRQQYGEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYSNGGNPTRV
GGVLPEMSAAIAGQASEAADDGGMTAIPVARIVDALENPGGKYQHNGKEQTYPNIKMIWWAGGGNFTHHQDTNRLIKAWQ
KPEMIVVSECYWTAAAKHADIVLPITTSFERNDLTMTGDYSNQHIVPMKQAVAAQFEARNDFDVFADLAELLKPGGKEIY
TEGKDEMAWLKFFYDAAQKGARAQRVTMPMFNAFWQQNKLIEMRRSEKNEQYVRYGDFRADPVKNALGTPSGKIEIYSKT
LEKFGYKDCPAHPTWLAPDEWKGTADEKQLQLLTAHPAHRLHSQLNYAELRKKYAVADREPITIHTEDAARFGIANGDLV
RVWNKRGQILTGAVVTDGIKKGVVCVHEGAWPDLENGLCKNGSANVLTADIPSSQLANACAGNSALVYIEKYTSNAPKLT
AFDQPAVQA

Sequences:

>Translated_809_residues
MTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRWGAMNVEVKDGKIVSSTGALAKTIPNSLQSTAADQVH
TTARIQHPMVRKSYLDNPLQPAKGRGEDTYVQVSWEQALKLIHEQHDRIRKANGPSAIFAGSYGWRSSGVLHKAQTLLQR
YMNLAGGYSGHSGDYSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPLNTLKIAWSSTDEQGLEYFHQLK
KSGKPVIAIDPIRSETIEFFGDNATWIAPNMGTDVALMLGIAHTLMTQGKHDKVFLEKYTTGYPQFEEYLTGKSDNTPKS
AAWAAEISGVPEAQIVKLAELMAANRTMLMAGWGIQRQQYGEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYSNGGNPTRV
GGVLPEMSAAIAGQASEAADDGGMTAIPVARIVDALENPGGKYQHNGKEQTYPNIKMIWWAGGGNFTHHQDTNRLIKAWQ
KPEMIVVSECYWTAAAKHADIVLPITTSFERNDLTMTGDYSNQHIVPMKQAVAAQFEARNDFDVFADLAELLKPGGKEIY
TEGKDEMAWLKFFYDAAQKGARAQRVTMPMFNAFWQQNKLIEMRRSEKNEQYVRYGDFRADPVKNALGTPSGKIEIYSKT
LEKFGYKDCPAHPTWLAPDEWKGTADEKQLQLLTAHPAHRLHSQLNYAELRKKYAVADREPITIHTEDAARFGIANGDLV
RVWNKRGQILTGAVVTDGIKKGVVCVHEGAWPDLENGLCKNGSANVLTADIPSSQLANACAGNSALVYIEKYTSNAPKLT
AFDQPAVQA
>Mature_808_residues
TLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRWGAMNVEVKDGKIVSSTGALAKTIPNSLQSTAADQVHT
TARIQHPMVRKSYLDNPLQPAKGRGEDTYVQVSWEQALKLIHEQHDRIRKANGPSAIFAGSYGWRSSGVLHKAQTLLQRY
MNLAGGYSGHSGDYSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPLNTLKIAWSSTDEQGLEYFHQLKK
SGKPVIAIDPIRSETIEFFGDNATWIAPNMGTDVALMLGIAHTLMTQGKHDKVFLEKYTTGYPQFEEYLTGKSDNTPKSA
AWAAEISGVPEAQIVKLAELMAANRTMLMAGWGIQRQQYGEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYSNGGNPTRVG
GVLPEMSAAIAGQASEAADDGGMTAIPVARIVDALENPGGKYQHNGKEQTYPNIKMIWWAGGGNFTHHQDTNRLIKAWQK
PEMIVVSECYWTAAAKHADIVLPITTSFERNDLTMTGDYSNQHIVPMKQAVAAQFEARNDFDVFADLAELLKPGGKEIYT
EGKDEMAWLKFFYDAAQKGARAQRVTMPMFNAFWQQNKLIEMRRSEKNEQYVRYGDFRADPVKNALGTPSGKIEIYSKTL
EKFGYKDCPAHPTWLAPDEWKGTADEKQLQLLTAHPAHRLHSQLNYAELRKKYAVADREPITIHTEDAARFGIANGDLVR
VWNKRGQILTGAVVTDGIKKGVVCVHEGAWPDLENGLCKNGSANVLTADIPSSQLANACAGNSALVYIEKYTSNAPKLTA
FDQPAVQA

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions. Can also reduce other N- and S-oxide compounds such as 4-methylmorpholine-N-oxide and biotin sulfoxide (BSO), but with a lower catalytic

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=809, Percent_Identity=99.0111248454883, Blast_Score=1667, Evalue=0.0,
Organism=Escherichia coli, GI145693196, Length=773, Percent_Identity=63.6481241914618, Blast_Score=1060, Evalue=0.0,
Organism=Escherichia coli, GI1787231, Length=786, Percent_Identity=45.1653944020356, Blast_Score=644, Evalue=0.0,
Organism=Escherichia coli, GI87081797, Length=752, Percent_Identity=30.9840425531915, Blast_Score=270, Evalue=3e-73,
Organism=Escherichia coli, GI1787870, Length=848, Percent_Identity=28.8915094339623, Blast_Score=269, Evalue=5e-73,
Organism=Escherichia coli, GI171474008, Length=840, Percent_Identity=28.5714285714286, Blast_Score=240, Evalue=3e-64,
Organism=Escherichia coli, GI3868721, Length=719, Percent_Identity=22.5312934631433, Blast_Score=106, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 88865; Mature: 88734

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2 ; PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRWGAMNVEVKDGKIVSST
CCCCHHHHHHHCCCCCCEEEEECCCCCCCCHHHCCCEEEEECCCCEEEEEECCCEEEECC
GALAKTIPNSLQSTAADQVHTTARIQHPMVRKSYLDNPLQPAKGRGEDTYVQVSWEQALK
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHH
LIHEQHDRIRKANGPSAIFAGSYGWRSSGVLHKAQTLLQRYMNLAGGYSGHSGDYSTGAA
HHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
QVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPLNTLKIAWSSTDEQGLEYFHQLK
HHHHHHHHCCEEEEECCCCCCEEEECCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHH
KSGKPVIAIDPIRSETIEFFGDNATWIAPNMGTDVALMLGIAHTLMTQGKHDKVFLEKYT
HCCCCEEEECCCCCHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHC
TGYPQFEEYLTGKSDNTPKSAAWAAEISGVPEAQIVKLAELMAANRTMLMAGWGIQRQQY
CCCCCHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHH
GEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYSNGGNPTRVGGVLPEMSAAIAGQASEAAD
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCC
DGGMTAIPVARIVDALENPGGKYQHNGKEQTYPNIKMIWWAGGGNFTHHQDTNRLIKAWQ
CCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHC
KPEMIVVSECYWTAAAKHADIVLPITTSFERNDLTMTGDYSNQHIVPMKQAVAAQFEARN
CCCEEEEECCHHHHHCCCCEEEEEEECCCCCCCCEEECCCCCCEECHHHHHHHHHHHCCC
DFDVFADLAELLKPGGKEIYTEGKDEMAWLKFFYDAAQKGARAQRVTMPMFNAFWQQNKL
CHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCHH
IEMRRSEKNEQYVRYGDFRADPVKNALGTPSGKIEIYSKTLEKFGYKDCPAHPTWLAPDE
HHHHHCCCCCCEEEECCCCCCHHHHHHCCCCCCEEEHHHHHHHCCCCCCCCCCCCCCCCC
WKGTADEKQLQLLTAHPAHRLHSQLNYAELRKKYAVADREPITIHTEDAARFGIANGDLV
CCCCCCHHHEEEEECCCHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCHHHCCCCCCCEE
RVWNKRGQILTGAVVTDGIKKGVVCVHEGAWPDLENGLCKNGSANVLTADIPSSQLANAC
EEECCCCCEEEEHHHHCCHHCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHH
AGNSALVYIEKYTSNAPKLTAFDQPAVQA
CCCCEEEEEEECCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
TLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRWGAMNVEVKDGKIVSST
CCCHHHHHHHCCCCCCEEEEECCCCCCCCHHHCCCEEEEECCCCEEEEEECCCEEEECC
GALAKTIPNSLQSTAADQVHTTARIQHPMVRKSYLDNPLQPAKGRGEDTYVQVSWEQALK
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHH
LIHEQHDRIRKANGPSAIFAGSYGWRSSGVLHKAQTLLQRYMNLAGGYSGHSGDYSTGAA
HHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
QVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPLNTLKIAWSSTDEQGLEYFHQLK
HHHHHHHHCCEEEEECCCCCCEEEECCCEEEEECCCCCCEEEEEECCCCHHHHHHHHHHH
KSGKPVIAIDPIRSETIEFFGDNATWIAPNMGTDVALMLGIAHTLMTQGKHDKVFLEKYT
HCCCCEEEECCCCCHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHC
TGYPQFEEYLTGKSDNTPKSAAWAAEISGVPEAQIVKLAELMAANRTMLMAGWGIQRQQY
CCCCCHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHH
GEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYSNGGNPTRVGGVLPEMSAAIAGQASEAAD
CCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCCCCCCC
DGGMTAIPVARIVDALENPGGKYQHNGKEQTYPNIKMIWWAGGGNFTHHQDTNRLIKAWQ
CCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHC
KPEMIVVSECYWTAAAKHADIVLPITTSFERNDLTMTGDYSNQHIVPMKQAVAAQFEARN
CCCEEEEECCHHHHHCCCCEEEEEEECCCCCCCCEEECCCCCCEECHHHHHHHHHHHCCC
DFDVFADLAELLKPGGKEIYTEGKDEMAWLKFFYDAAQKGARAQRVTMPMFNAFWQQNKL
CHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCHH
IEMRRSEKNEQYVRYGDFRADPVKNALGTPSGKIEIYSKTLEKFGYKDCPAHPTWLAPDE
HHHHHCCCCCCEEEECCCCCCHHHHHHCCCCCCEEEHHHHHHHCCCCCCCCCCCCCCCCC
WKGTADEKQLQLLTAHPAHRLHSQLNYAELRKKYAVADREPITIHTEDAARFGIANGDLV
CCCCCCHHHEEEEECCCHHHHHHCCCHHHHHHHHHCCCCCCEEEEECCHHHCCCCCCCEE
RVWNKRGQILTGAVVTDGIKKGVVCVHEGAWPDLENGLCKNGSANVLTADIPSSQLANAC
EEECCCCCEEEEHHHHCCHHCCEEEEECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHH
AGNSALVYIEKYTSNAPKLTAFDQPAVQA
CCCCEEEEEEECCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]