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The map label for this gene is ydjJ [H]

Identifier: 218705272

GI number: 218705272

Start: 2090994

End: 2092037

Strand: Reverse

Name: ydjJ [H]

Synonym: ECUMN_2063

Alternate gene names: 218705272

Gene position: 2092037-2090994 (Counterclockwise)

Preceding gene: 218705273

Following gene: 218705271

Centisome position: 40.22

GC content: 46.07

Gene sequence:

>1044_bases
ATGAAAAATTCAAAAGCAATATTGCAGGTGCCGGGCACAATGAAAATTATTTCAGCAGAAATACCTGTGCCTAAAGAAGA
TGAAGTTTTGATTAAAGTGGAATATGTCGGTATTTGTGGTTCAGATGTACATGGTTTTGAATCAGGCCCGTTTATTCCGC
CTAAAGACCCAAATCAAGAAATTGGCCTGGGTCATGAATGCGCCGGGACGGTTGTGGCTGTGGGAAGCCGAGTGCGCAAA
TTTAAACCGGGGGATCGAGTAAATATCGAACCTGGCGTTCCTTGCGGTCACTGTCGTTACTGTCTGGAAGGCAAATATAA
CATCTGCCCGGACGTTGATTTTATGGCGACACAACCTAACTACCGCGGCGCATTAACGCACTATCTGTGTCATCCGGAGA
GCTTTACTTACAAACTGCCCGACAATATGGACATGATGGAAGGGGCGCTGGTGGAGCCTGCTGCAGTCGGGATGCATGCC
GCGATGCTGGCAGATGTTAAACCGGGTAAGAAGATAATTATTCTGGGAGCGGGTTGTATTGGTTTGATGACGTTGCAAGC
GTGCAAATGCCTGGGAGCTACGGATATTGCCGTCGTTGATGTACTGGATAAACGTCTGACAATGGCGGAACAGCTCGGCG
CGACAGTGGTTATTAACGGTGCAAAAGAAGACACTATTGCACGCTGTCAGCAATTTACCGAAGAAATGGGCGCAGATATT
GTTTTCGAAACAGCGGGTTCTGCGGTCACCGTTAAACAGGCACCTTATCTGGTAATGCGCGGCGGTAAAATTATGATTGT
TGGTACTGTACCGGGCGATTCGGCAATCAATTTCCTCAAAATCAATCGCGAAGTCACTATTCAGACAGTATTCCGCTATG
CCAATCGTTATCCGGTCACGATTGAAGCTATTTCCTCAGGGCGATTCGATGTGAAATCGATGGTGACACATATTTACGAT
TATCAGGATGTACAACAGGCATTTGAAGAGTCGGTTAACAACAAACGCGACATTATTAAAGGCGTTATTAAAATTAGCGA
TTAA

Upstream 100 bases:

>100_bases
GCAATTGCTATCGCCACCATTGGAATTGAAACCAAAGGTGTCTCCGTTGAAAGTTTAAGTATTGATGCAGTAGTCAATAA
ATAATACTGGTGGATTCAAA

Downstream 100 bases:

>100_bases
TTAATACGGGAGAACAGAATATGCTCGCAGATATCAGATATTGGGAAAACGATGCCACAAATAAACATTATGCAATTGCC
CATTTTAACGTATGGAATGC

Product: putative iditol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKNSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRK
FKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDMMEGALVEPAAVGMHA
AMLADVKPGKKIIILGAGCIGLMTLQACKCLGATDIAVVDVLDKRLTMAEQLGATVVINGAKEDTIARCQQFTEEMGADI
VFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGDSAINFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYD
YQDVQQAFEESVNNKRDIIKGVIKISD

Sequences:

>Translated_347_residues
MKNSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRK
FKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDMMEGALVEPAAVGMHA
AMLADVKPGKKIIILGAGCIGLMTLQACKCLGATDIAVVDVLDKRLTMAEQLGATVVINGAKEDTIARCQQFTEEMGADI
VFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGDSAINFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYD
YQDVQQAFEESVNNKRDIIKGVIKISD
>Mature_347_residues
MKNSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRK
FKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDMMEGALVEPAAVGMHA
AMLADVKPGKKIIILGAGCIGLMTLQACKCLGATDIAVVDVLDKRLTMAEQLGATVVINGAKEDTIARCQQFTEEMGADI
VFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGDSAINFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYD
YQDVQQAFEESVNNKRDIIKGVIKISD

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=333, Percent_Identity=38.1381381381381, Blast_Score=224, Evalue=7e-59,
Organism=Homo sapiens, GI4501929, Length=355, Percent_Identity=26.4788732394366, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI34577061, Length=354, Percent_Identity=27.1186440677966, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI156523966, Length=361, Percent_Identity=27.1468144044321, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI4501939, Length=361, Percent_Identity=27.1468144044321, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI71565154, Length=369, Percent_Identity=26.5582655826558, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI71743840, Length=340, Percent_Identity=25.8823529411765, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI262073058, Length=340, Percent_Identity=25.8823529411765, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1788073, Length=347, Percent_Identity=98.2708933717579, Blast_Score=702, Evalue=0.0,
Organism=Escherichia coli, GI1790045, Length=329, Percent_Identity=29.1793313069909, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1788407, Length=336, Percent_Identity=29.7619047619048, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787863, Length=345, Percent_Identity=27.536231884058, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788075, Length=339, Percent_Identity=28.023598820059, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790718, Length=308, Percent_Identity=29.5454545454545, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI226510992, Length=343, Percent_Identity=28.5714285714286, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI87082125, Length=269, Percent_Identity=30.4832713754647, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786552, Length=367, Percent_Identity=28.0653950953678, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87081918, Length=259, Percent_Identity=30.5019305019305, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562876, Length=349, Percent_Identity=36.3896848137536, Blast_Score=227, Evalue=7e-60,
Organism=Caenorhabditis elegans, GI17562878, Length=345, Percent_Identity=36.8115942028986, Blast_Score=203, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI71988145, Length=260, Percent_Identity=30.7692307692308, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17562584, Length=273, Percent_Identity=30.03663003663, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562582, Length=274, Percent_Identity=25.9124087591241, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323099, Length=350, Percent_Identity=36.5714285714286, Blast_Score=212, Evalue=8e-56,
Organism=Saccharomyces cerevisiae, GI6322619, Length=352, Percent_Identity=34.9431818181818, Blast_Score=199, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6319955, Length=352, Percent_Identity=34.9431818181818, Blast_Score=198, Evalue=9e-52,
Organism=Saccharomyces cerevisiae, GI6319257, Length=353, Percent_Identity=30.5949008498584, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6319258, Length=361, Percent_Identity=27.1468144044321, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320033, Length=366, Percent_Identity=27.0491803278689, Blast_Score=106, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6319621, Length=334, Percent_Identity=27.8443113772455, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323729, Length=298, Percent_Identity=26.510067114094, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323961, Length=309, Percent_Identity=26.8608414239482, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324486, Length=289, Percent_Identity=26.2975778546713, Blast_Score=86, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17137530, Length=350, Percent_Identity=39.4285714285714, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI17737897, Length=353, Percent_Identity=38.5269121813031, Blast_Score=224, Evalue=8e-59,
Organism=Drosophila melanogaster, GI45550770, Length=327, Percent_Identity=26.9113149847095, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI45551930, Length=327, Percent_Identity=26.9113149847095, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI221457811, Length=327, Percent_Identity=26.9113149847095, Blast_Score=118, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 37719; Mature: 37719

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00059 ADH_ZINC ; PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQE
CCCCCEEEECCCCEEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
IGLGHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPN
CCCCCHHCCHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHEECCCCCCCCCCCEEECCCC
YRGALTHYLCHPESFTYKLPDNMDMMEGALVEPAAVGMHAAMLADVKPGKKIIILGAGCI
CCCCCEEEEECCCCEEEECCCCCCHHCCCCCCHHHHHHHHHHHEECCCCCEEEEEECCHH
GLMTLQACKCLGATDIAVVDVLDKRLTMAEQLGATVVINGAKEDTIARCQQFTEEMGADI
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCE
VFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGDSAINFLKINREVTIQTVFRYANRYPVT
EEECCCCEEEEECCCEEEEECCEEEEEEECCCCCCEEEEEECCEEEHHHHHHHHCCCCEE
IEAISSGRFDVKSMVTHIYDYQDVQQAFEESVNNKRDIIKGVIKISD
EEEECCCCCCHHHHHHHHHCHHHHHHHHHHHCCCHHHHHEEEEEECC
>Mature Secondary Structure
MKNSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQE
CCCCCEEEECCCCEEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
IGLGHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPN
CCCCCHHCCHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHEECCCCCCCCCCCEEECCCC
YRGALTHYLCHPESFTYKLPDNMDMMEGALVEPAAVGMHAAMLADVKPGKKIIILGAGCI
CCCCCEEEEECCCCEEEECCCCCCHHCCCCCCHHHHHHHHHHHEECCCCCEEEEEECCHH
GLMTLQACKCLGATDIAVVDVLDKRLTMAEQLGATVVINGAKEDTIARCQQFTEEMGADI
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCE
VFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGDSAINFLKINREVTIQTVFRYANRYPVT
EEECCCCEEEEECCCEEEEECCEEEEEEECCCCCCEEEEEECCEEEHHHHHHHHCCCCEE
IEAISSGRFDVKSMVTHIYDYQDVQQAFEESVNNKRDIIKGVIKISD
EEEECCCCCCHHHHHHHHHCHHHHHHHHHHHCCCHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]