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The map label for this gene is safA [H]

Identifier: 218704971

GI number: 218704971

Start: 1781732

End: 1781965

Strand: Reverse

Name: safA [H]

Synonym: ECUMN_1754

Alternate gene names: 218704971

Gene position: 1781965-1781732 (Counterclockwise)

Preceding gene: 218704972

Following gene: 218704970

Centisome position: 34.25

GC content: 35.9

Gene sequence:

>234_bases
ATGATTAACGTCATTCGTTTAATAAACACATTTGAAATGCATGCGACCATAGTGAAAAATAAAATCACGCAAAGAGACAA
CTATAAAGGGATCATGTCTGTAATTGTGGTTGTCTTATTACTGACCCTTACATTGATAGCCATTTTTTCGGCAATTGATC
AGCTGGGTATTTCAGAAATGGGGCGCATTGCAAGGGATCTTACACATTTCATTATCAATAGTTTGCAAGACTGA

Upstream 100 bases:

>100_bases
ATACCTCCGCCTACAGCTGTAAGAAACTCCGCTCAGTACTGAAGCGCCAGTCCTATTTCCTCTATTCTCCAGCCTGTTAT
ATTAAGCATACTGATTAACG

Downstream 100 bases:

>100_bases
AAATAAACAGCAAATTATAAATATGAAATGTTAAAAAAGTATCGATAAAAACTTTATTGTTTTAAGGAGATAAAATGTCG
CTCGTTTGTTCTGTTATATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 77; Mature: 77

Protein sequence:

>77_residues
MINVIRLINTFEMHATIVKNKITQRDNYKGIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIINSLQD

Sequences:

>Translated_77_residues
MINVIRLINTFEMHATIVKNKITQRDNYKGIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIINSLQD
>Mature_77_residues
MINVIRLINTFEMHATIVKNKITQRDNYKGIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIINSLQD

Specific function: Connects the signal transduction between the two- component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SafA family [H]

Homologues:

Organism=Escherichia coli, GI1787777, Length=64, Percent_Identity=93.75, Blast_Score=92, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 8713; Mature: 8713

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINVIRLINTFEMHATIVKNKITQRDNYKGIMSVIVVVLLLTLTLIAIFSAIDQLGISEM
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
GRIARDLTHFIINSLQD
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MINVIRLINTFEMHATIVKNKITQRDNYKGIMSVIVVVLLLTLTLIAIFSAIDQLGISEM
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
GRIARDLTHFIINSLQD
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12384590; 12704152 [H]