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The map label for this gene is pqqL [H]

Identifier: 218704965

GI number: 218704965

Start: 1770376

End: 1773171

Strand: Reverse

Name: pqqL [H]

Synonym: ECUMN_1748

Alternate gene names: 218704965

Gene position: 1773171-1770376 (Counterclockwise)

Preceding gene: 218704966

Following gene: 218704964

Centisome position: 34.09

GC content: 46.92

Gene sequence:

>2796_bases
ATGGAGATAATTATGAGAAACCTCTGTTTCTTACTGACGTTAGTGGCAACTCTGTTGCTCCCCGGGCGACTGATTGCCGC
CGCCTTACCGCAGGATGAAAAGTTAATTACCGGGCAACTGGACAATGGCTTGCGATATATGATTTATCCGCATGCTCAAC
CAAAGGATCAGGTAAATTTATGGCTGCAAATTCATACCGGTTCATTGCAGGAAGAGGACAATGAGCGCGGCGTGGCTCAT
TTTGTAGAACATATGATGTTTAACGGCACAAAAACATGGCCGGGTAATAAAGTCATCGAAACATTTGAGTCAATGGGCCT
GCGTTTTGGTCGCGATGTTAATGCCTATACCAGCTATGACGAAACGGTGTATCAGGTGAGTTTGCCGACTACGCAGAAAC
AAAATCTGCAACAAGTGATGGCAATCTTCAGTGAATGGAGTAATGCCGCAACCTTTGAAAAACTCGAAGTAGACGCTGAA
CGTGGCGTAATTACTGAGGAATGGCGTGCCCATCAGGATGCGAAATGGCGCACCTCTCAGGCGCGCCGCCCTTTCCTGCT
GGCTAATACCCGTAATTTAGACCGTGAACCTATCGGCCTGATGGATACTGTCGCTACGGTCACACCGGCACAATTGCGCC
AATTTTATCAACGCTGGTATCAACCAAATAATATGACCTTTATCGTGGTCGGCGATATCGACAGTAAAGAAGCGCTGGCG
CTGATAAAGGACAATTTAAGTAAGCTTCCGGCTAACAAAGCAGCTGAAAATCGCGTCTGGCCGACAAAAGCCGAAAACCA
CCTGCGCTTTAATATCATTAAGGATAAAGAAAACCGGGTGAACGGCATCGCACTCTATTATCGCCTGCCAATGGTGCAAG
TGAGCGATGAGCAAAGCTTTATCGAACAAGCTGAATGGAGCATGTTGGTTCAGCTGTTCAATCAGCGTCTGCAGGAACGC
ATACAGTCGGGCGAGTTGAAGACTATTTCTGGCGGCACTGCGCGCAGCGTTAAAATTGCACCCGATTATCAGTCGCTGTT
TTTCCGTGTAAATGCACGAGACGATAATATGCAGGATGCTGCGAATGCATTAATGGCAGAGTTGGCAACTATTGATCAGC
ATGGTTTTTCTGCTGAAGAACTCGATGATGTCAAATCTACCCGCCTCACCTGGCTGAAAAATGCGGTTGATCAGCAAGCT
GAACGTGATTTACGTATGCTGACCAGTCGCCTGGCATCCAGCTCATTAAATAATACGCCGTTCTTGTCGCCGGAAGAGAC
ATATCAACTTTCGAAACGTCTGTGGCAGCAAATTACCGTGCAAAGTCTGGCGGAAAAATGGCAGCAGTTAAGAAAGAACC
AGGATGCATTTTGGGAGCAAATGGTAAACAATGAGGTTGCTGCCAAAAAAGCATTGTCTCCTGCGGCTATCCTGGCGCTG
GAAAAAGAGTACGCCAACAAAAAGCTGGCGGCTTACATCTTCCCAGGCAGAAATTTATCGTTAACAGTAGACGCTGACCC
ACAGGCGGAAATTAGCAGCAAAGAAACGCTGGCTGAGAATCTGACATCATTAACACTTTCCAATGGTGCCAGGGTTATTC
TGGCAAAATCCGCGGGTGAAGAGCAAAAGCTACAAATTACTGCCGTATCGAATAAAGGCGATTTAAGTTTCCCTGCGCAG
CAAAAATCACTTATCGCGCTGGCAAATAAAGCAGTAAGCGGAAGCGGCGTTGGTGAACTCTCCTCTTCCAGCCTGAAACG
CTGGAGTGCGGAAAACTCGGTAACCATGAGCAGTAAAGTCAGTGGCATGAATACGTTGCTCTCCGTTAGCGCGCGGGCTA
ATAACCCTGAACCTGGTTTTCAGTTGATTAACCAGCGAATCACCCACAGCACGATTAACGATAATATTTGGGCATCGCTA
CAAAATGCTCAAATTCAGGCGTTGAAAACACTCGACCAGCGTCCAGCGGAGAAATTCGCCCAGCAGATGTATGAGACGCG
CTATGCTGATGACCGCACGAAATTACTGCAAGAAAATCAGATTGCACAGTTTACTGCCGCAGATGCGCTGGCTGCCGATC
GCAAGTTGTTTTCATCTCCAGCGGATATCACGTTTGTCATTGTCGGTAATGTCGCAGAAGACAAACTCGTGGCGTTAATT
ACGCGTTACTTAGGATCAATCAAACACTCTGATTCGCCATTAGCCGCAGGTAAACCATTAACTCGCGCGACGGACAACGC
ATCGGTTACTGTAAAAGAACAAAATGAACCTGTGGCACAGGTTTCACAGTGGAAGCGTTATGATTCCCGGACACCGGTTA
ATCTGGCGATGCGTATGGCGCTCGATGCTTTTAACGTCGCACTGGCAAAAGATCTACGCATTAATATTCGTGAACAGGCC
TCTGGGGCATACAGCGTTTCTTCTCGCCTCTCGGTTGATCCTCAGGCCAAAGATATCAGTCATTTGCTGGCTTTTACTTG
TCAACCGGAACGACATGATGAACTGTTAACGTTAGCGAATGAAGTGATGGTTAAGCGTCTGGCTAAAGGGATCAGTGAGC
AAGAACTGAACGAATACCAGCAAAACGTTCAGCGCAGCCTCGATATCCAACAGCGTAGCGTTCAACAATTAGCGAACACC
ATTGTAAATAGTCTTATTCAATATGACGATCCTGCAGCATGGACTGAGCAGGAGCAATTGTTGAAACAAATGACGGTAGA
GAATGTTAACACTGCCGTTAAACAATATCTTTCTCATCCGGTGAATACCTATACCGGAGTATTATTGCCAAAATAA

Upstream 100 bases:

>100_bases
TGGCGACCTACGCCAGTGGCCGTACTTTCTGGCTTGATGTCAGCATGAAATTTTAATAGTTCGGATTTTACTTAACCGGG
TAAATTTGCCCGGTTTTCGC

Downstream 100 bases:

>100_bases
TAACAGCCCCGTCAACACCTCGTTGGCGGGGGATTTTAGCAATATTCGCTATTTTTATGTAATAATTTTATAAATGCGTT
CAAAATAATAACCAAGTACT

Product: putative membrane-associated peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 931; Mature: 931

Protein sequence:

>931_residues
MEIIMRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLDNGLRYMIYPHAQPKDQVNLWLQIHTGSLQEEDNERGVAH
FVEHMMFNGTKTWPGNKVIETFESMGLRFGRDVNAYTSYDETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAE
RGVITEEWRAHQDAKWRTSQARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQPNNMTFIVVGDIDSKEALA
LIKDNLSKLPANKAAENRVWPTKAENHLRFNIIKDKENRVNGIALYYRLPMVQVSDEQSFIEQAEWSMLVQLFNQRLQER
IQSGELKTISGGTARSVKIAPDYQSLFFRVNARDDNMQDAANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAVDQQA
ERDLRMLTSRLASSSLNNTPFLSPEETYQLSKRLWQQITVQSLAEKWQQLRKNQDAFWEQMVNNEVAAKKALSPAAILAL
EKEYANKKLAAYIFPGRNLSLTVDADPQAEISSKETLAENLTSLTLSNGARVILAKSAGEEQKLQITAVSNKGDLSFPAQ
QKSLIALANKAVSGSGVGELSSSSLKRWSAENSVTMSSKVSGMNTLLSVSARANNPEPGFQLINQRITHSTINDNIWASL
QNAQIQALKTLDQRPAEKFAQQMYETRYADDRTKLLQENQIAQFTAADALAADRKLFSSPADITFVIVGNVAEDKLVALI
TRYLGSIKHSDSPLAAGKPLTRATDNASVTVKEQNEPVAQVSQWKRYDSRTPVNLAMRMALDAFNVALAKDLRINIREQA
SGAYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLANEVMVKRLAKGISEQELNEYQQNVQRSLDIQQRSVQQLANT
IVNSLIQYDDPAAWTEQEQLLKQMTVENVNTAVKQYLSHPVNTYTGVLLPK

Sequences:

>Translated_931_residues
MEIIMRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLDNGLRYMIYPHAQPKDQVNLWLQIHTGSLQEEDNERGVAH
FVEHMMFNGTKTWPGNKVIETFESMGLRFGRDVNAYTSYDETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAE
RGVITEEWRAHQDAKWRTSQARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQPNNMTFIVVGDIDSKEALA
LIKDNLSKLPANKAAENRVWPTKAENHLRFNIIKDKENRVNGIALYYRLPMVQVSDEQSFIEQAEWSMLVQLFNQRLQER
IQSGELKTISGGTARSVKIAPDYQSLFFRVNARDDNMQDAANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAVDQQA
ERDLRMLTSRLASSSLNNTPFLSPEETYQLSKRLWQQITVQSLAEKWQQLRKNQDAFWEQMVNNEVAAKKALSPAAILAL
EKEYANKKLAAYIFPGRNLSLTVDADPQAEISSKETLAENLTSLTLSNGARVILAKSAGEEQKLQITAVSNKGDLSFPAQ
QKSLIALANKAVSGSGVGELSSSSLKRWSAENSVTMSSKVSGMNTLLSVSARANNPEPGFQLINQRITHSTINDNIWASL
QNAQIQALKTLDQRPAEKFAQQMYETRYADDRTKLLQENQIAQFTAADALAADRKLFSSPADITFVIVGNVAEDKLVALI
TRYLGSIKHSDSPLAAGKPLTRATDNASVTVKEQNEPVAQVSQWKRYDSRTPVNLAMRMALDAFNVALAKDLRINIREQA
SGAYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLANEVMVKRLAKGISEQELNEYQQNVQRSLDIQQRSVQQLANT
IVNSLIQYDDPAAWTEQEQLLKQMTVENVNTAVKQYLSHPVNTYTGVLLPK
>Mature_931_residues
MEIIMRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLDNGLRYMIYPHAQPKDQVNLWLQIHTGSLQEEDNERGVAH
FVEHMMFNGTKTWPGNKVIETFESMGLRFGRDVNAYTSYDETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAE
RGVITEEWRAHQDAKWRTSQARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQPNNMTFIVVGDIDSKEALA
LIKDNLSKLPANKAAENRVWPTKAENHLRFNIIKDKENRVNGIALYYRLPMVQVSDEQSFIEQAEWSMLVQLFNQRLQER
IQSGELKTISGGTARSVKIAPDYQSLFFRVNARDDNMQDAANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAVDQQA
ERDLRMLTSRLASSSLNNTPFLSPEETYQLSKRLWQQITVQSLAEKWQQLRKNQDAFWEQMVNNEVAAKKALSPAAILAL
EKEYANKKLAAYIFPGRNLSLTVDADPQAEISSKETLAENLTSLTLSNGARVILAKSAGEEQKLQITAVSNKGDLSFPAQ
QKSLIALANKAVSGSGVGELSSSSLKRWSAENSVTMSSKVSGMNTLLSVSARANNPEPGFQLINQRITHSTINDNIWASL
QNAQIQALKTLDQRPAEKFAQQMYETRYADDRTKLLQENQIAQFTAADALAADRKLFSSPADITFVIVGNVAEDKLVALI
TRYLGSIKHSDSPLAAGKPLTRATDNASVTVKEQNEPVAQVSQWKRYDSRTPVNLAMRMALDAFNVALAKDLRINIREQA
SGAYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLANEVMVKRLAKGISEQELNEYQQNVQRSLDIQQRSVQQLANT
IVNSLIQYDDPAAWTEQEQLLKQMTVENVNTAVKQYLSHPVNTYTGVLLPK

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=216, Percent_Identity=25.462962962963, Blast_Score=75, Evalue=4e-13,
Organism=Escherichia coli, GI1787770, Length=931, Percent_Identity=98.8184747583244, Blast_Score=1893, Evalue=0.0,
Organism=Escherichia coli, GI1789946, Length=464, Percent_Identity=21.1206896551724, Blast_Score=81, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533970, Length=248, Percent_Identity=26.2096774193548, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324474, Length=192, Percent_Identity=26.0416666666667, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 104669; Mature: 104669

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIIMRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLDNGLRYMIYPHAQPKDQVNL
CHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEECCCCCCCEEEEECCCCCCCCEEE
WLQIHTGSLQEEDNERGVAHFVEHMMFNGTKTWPGNKVIETFESMGLRFGRDVNAYTSYD
EEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHCCCCCCCCCCCC
ETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAERGVITEEWRAHQDAKWRTSQ
CEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHEEHHHCCCCCHHHHCCCCCCHHHHH
ARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQPNNMTFIVVGDIDSKEALA
CCCCEEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHH
LIKDNLSKLPANKAAENRVWPTKAENHLRFNIIKDKENRVNGIALYYRLPMVQVSDEQSF
HHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEEECEEEECCHHHH
IEQAEWSMLVQLFNQRLQERIQSGELKTISGGTARSVKIAPDYQSLFFRVNARDDNMQDA
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCHHHEEEEEECCCCCHHHH
ANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAVDQQAERDLRMLTSRLASSSLNNTP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FLSPEETYQLSKRLWQQITVQSLAEKWQQLRKNQDAFWEQMVNNEVAAKKALSPAAILAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHCCCCHHHHHH
EKEYANKKLAAYIFPGRNLSLTVDADPQAEISSKETLAENLTSLTLSNGARVILAKSAGE
HHHHCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHEEECCCCEEEEEECCCC
EQKLQITAVSNKGDLSFPAQQKSLIALANKAVSGSGVGELSSSSLKRWSAENSVTMSSKV
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEEEHHHH
SGMNTLLSVSARANNPEPGFQLINQRITHSTINDNIWASLQNAQIQALKTLDQRPAEKFA
CCHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
QQMYETRYADDRTKLLQENQIAQFTAADALAADRKLFSSPADITFVIVGNVAEDKLVALI
HHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
TRYLGSIKHSDSPLAAGKPLTRATDNASVTVKEQNEPVAQVSQWKRYDSRTPVNLAMRMA
HHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHH
LDAFNVALAKDLRINIREQASGAYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLAN
HHHHHHHHHHHHEEEEHHHCCCCEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
EVMVKRLAKGISEQELNEYQQNVQRSLDIQQRSVQQLANTIVNSLIQYDDPAAWTEQEQL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LKQMTVENVNTAVKQYLSHPVNTYTGVLLPK
HHHHHHHHHHHHHHHHHCCCCHHHCCCEECC
>Mature Secondary Structure
MEIIMRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLDNGLRYMIYPHAQPKDQVNL
CHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEECCCCCCCEEEEECCCCCCCCEEE
WLQIHTGSLQEEDNERGVAHFVEHMMFNGTKTWPGNKVIETFESMGLRFGRDVNAYTSYD
EEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHCCCCCCCCCCCC
ETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAERGVITEEWRAHQDAKWRTSQ
CEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHEEHHHCCCCCHHHHCCCCCCHHHHH
ARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQPNNMTFIVVGDIDSKEALA
CCCCEEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHH
LIKDNLSKLPANKAAENRVWPTKAENHLRFNIIKDKENRVNGIALYYRLPMVQVSDEQSF
HHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEEECEEEECCHHHH
IEQAEWSMLVQLFNQRLQERIQSGELKTISGGTARSVKIAPDYQSLFFRVNARDDNMQDA
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCHHHEEEEEECCCCCHHHH
ANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAVDQQAERDLRMLTSRLASSSLNNTP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FLSPEETYQLSKRLWQQITVQSLAEKWQQLRKNQDAFWEQMVNNEVAAKKALSPAAILAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHCCCCHHHHHH
EKEYANKKLAAYIFPGRNLSLTVDADPQAEISSKETLAENLTSLTLSNGARVILAKSAGE
HHHHCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHEEECCCCEEEEEECCCC
EQKLQITAVSNKGDLSFPAQQKSLIALANKAVSGSGVGELSSSSLKRWSAENSVTMSSKV
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEEEHHHH
SGMNTLLSVSARANNPEPGFQLINQRITHSTINDNIWASLQNAQIQALKTLDQRPAEKFA
CCHHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
QQMYETRYADDRTKLLQENQIAQFTAADALAADRKLFSSPADITFVIVGNVAEDKLVALI
HHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
TRYLGSIKHSDSPLAAGKPLTRATDNASVTVKEQNEPVAQVSQWKRYDSRTPVNLAMRMA
HHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHH
LDAFNVALAKDLRINIREQASGAYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLAN
HHHHHHHHHHHHEEEEHHHCCCCEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
EVMVKRLAKGISEQELNEYQQNVQRSLDIQQRSVQQLANTIVNSLIQYDDPAAWTEQEQL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LKQMTVENVNTAVKQYLSHPVNTYTGVLLPK
HHHHHHHHHHHHHHHHHCCCCHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]