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The map label for this gene is kdpA [H]

Identifier: 218704019

GI number: 218704019

Start: 834623

End: 836296

Strand: Reverse

Name: kdpA [H]

Synonym: ECUMN_0780

Alternate gene names: 218704019

Gene position: 836296-834623 (Counterclockwise)

Preceding gene: 218704026

Following gene: 218704018

Centisome position: 16.08

GC content: 55.44

Gene sequence:

>1674_bases
ATGACTGCGCAAGGGTTCTTACTGATCGCCACGTTTTTACTGGTGTTAATGGTGCTGGCACGTCCTTTAGGCAGCGGGCT
GGCGCGGCTGATTAATGACATACCTCTTCCCGGTACAGCGGGTGTTGAACGCGTACTCTTTCGTTTACCTGGCGTCTCTG
ACAGTGAGATGAACTGGAAGCAATATCTCTGTGCCATTCTCGGCCTGAACATGCTGGGGCTGGCGGTGCTGTTTTTTATG
TTGCTCGGTCAGCACTATCTGCCGCTTAACCCACAGCAGTTGCCGGGGCTGTCGTGGGATCTGGCGCTGAATACTGCCGT
CAGCTTTGTCACCAATACCAACTGGCAATCTTACAGCGGTGAAACCACGTTGAGCTATTTCAGCCAGATGGCGGGCTTAA
CGGTGCAAAACTTTCTTTCTGCCGCCAGCGGGATTGCGGTGATTTTTGCCCTCATTCGTGCATTTACCCGCCAGAGCATG
AGCACACTCGGGAATGCCTGGGTCGATCTGCTACGCATCACGTTATGGGTGCTAGTCCCTGTGGCGTTGTTGATCGCACT
GTTTTTTATTCAACAAGGTGCGCTGCAAAACTTTCTGCCCTATCAGGCAGTGAATACCGTTGAAGGAGCGCAACAGCTGT
TACCCATGGGTCCGGTGGCTTCTCAGGAAGCGATAAAGATGCTCGGCACTAACGGCGGTGGCTTCTTTAATGCCAACTCG
TCGCATCCGTTTGAAAACCCAACCGCACTGACCAACTTCGTGCAGATGCTGGCGATCTTCTTGATCCCAACGGCACTGTG
CTTTGCCTTTGGCGAAGTGGCGGGCGATCGCCGTCAGGGGCGCATGTTGCTGTGGGCGATGTCAGTGATTTTTGTCATCT
GCGTAGGCGTGGTGATGTGGGCAGAAGTTCAGGGTAATCCTCATCTGCTGGCGCTGGGTGCGGACAGCAGCATCAATATG
GAAGGTAAAGAGAGCCGTTTCGGCGTGCTGGTCAGTAGCCTGTTTGCGGTCGTGACTACGGCGGCTTCCTGTGGCGCGGT
GATTGCGATGCATGATTCGTTTACCGCTCTCGGTGGCATGGTGCCGATGTGGCTGATGCAAATTGGTGAAGTGGTATTCG
GCGGTGTCGGTTCTGGTCTTTACGGCATGATGCTGTTTGTTCTGCTGGCGGTGTTTATTGCCGGGCTGATGATTGGTCGT
ACACCGGAATATCTGGGTAAAAAAATCGACGTACGTGAGATGAAACTGACCGCGCTGGCGATTCTGGTCACCCCGACGCT
GGTGCTGATGGGCGCGGCGCTGGCAATGATGACCGACGCCGGACGTAGCGCCATGCTCAACCCTGGCCCGCATGGTTTTA
GCGAAGTGCTGTACGCCGTGTCATCCGCCGCTAACAACAACGGCAGCGCCTTTGCCGGATTAAGCGCCAACTCTCCGTTC
TGGAACTGTTTACTGGCGTTCTGCATGTTTGTTGGTCGCTTCGGGGTGATTATCCCGGTGATGGCAATTGCCGGTTCGCT
GGTGAGTAAAAAGAGCCAACCCGCCAGCTCCGGCACGCTGCCAACGCACGGCCCGCTGTTTGTTGGCCTGTTAATCGGCA
CCGTGTTGCTGGTTGGCGCACTGACCTTTATCCCTGCCCTGGCGCTTGGTCCGGTGGCGGAATATCTCTCCTGA

Upstream 100 bases:

>100_bases
GGAGGTGCACTGTGAGTGCAGGCGTGATAGCCGGCGTGTTGCTGGTGTTTTTATTACTGGGTTATCTGGTTTATGCCCTG
ATCAATGCGGAGGCGTTCTG

Downstream 100 bases:

>100_bases
TGATATTGAGTGAGCACTGAATATGAGTCGTAAACAACTGGCGCTATTCGAACCAACACTTGTCCTTCAGGCGCTGAAAG
AAGCGGTGAAAAAATTAAAC

Product: potassium-transporting ATPase subunit A

Products: NA

Alternate protein names: ATP phosphohydrolase [potassium-transporting] A chain; Potassium-binding and translocating subunit A; Potassium-translocating ATPase A chain [H]

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MTAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVERVLFRLPGVSDSEMNWKQYLCAILGLNMLGLAVLFFM
LLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSM
STLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANS
SHPFENPTALTNFVQMLAIFLIPTALCFAFGEVAGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINM
EGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGR
TPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPF
WNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS

Sequences:

>Translated_557_residues
MTAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVERVLFRLPGVSDSEMNWKQYLCAILGLNMLGLAVLFFM
LLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSM
STLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANS
SHPFENPTALTNFVQMLAIFLIPTALCFAFGEVAGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINM
EGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGR
TPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPF
WNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS
>Mature_556_residues
TAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVERVLFRLPGVSDSEMNWKQYLCAILGLNMLGLAVLFFML
LGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMS
TLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANSS
HPFENPTALTNFVQMLAIFLIPTALCFAFGEVAGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINME
GKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRT
PEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFW
NCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS

Specific function: One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions [H]

COG id: COG2060

COG function: function code P; K+-transporting ATPase, A chain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdpA family [H]

Homologues:

Organism=Escherichia coli, GI1786915, Length=557, Percent_Identity=98.5637342908438, Blast_Score=1089, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004623 [H]

Pfam domain/function: PF03814 KdpA [H]

EC number: =3.6.3.12 [H]

Molecular weight: Translated: 59083; Mature: 58952

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVERVLFRLPGVSDSEMNWK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHH
QYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
ETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMSTLGNAWVDLLRITLWVLVP
CHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALLIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCC
SHPFENPTALTNFVQMLAIFLIPTALCFAFGEVAGDRRQGRMLLWAMSVIFVICVGVVMW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHH
AEVQGNPHLLALGADSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGM
HHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHH
VPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHH
ILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCHH
WNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LTFIPALALGPVAEYLS
HHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTAGVERVLFRLPGVSDSEMNWK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCHH
QYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
ETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMSTLGNAWVDLLRITLWVLVP
CHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VALLIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCC
SHPFENPTALTNFVQMLAIFLIPTALCFAFGEVAGDRRQGRMLLWAMSVIFVICVGVVMW
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHH
AEVQGNPHLLALGADSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGM
HHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHH
VPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHH
ILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCCCHH
WNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LTFIPALALGPVAEYLS
HHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA