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The map label for this gene is fepB [H]

Identifier: 218703927

GI number: 218703927

Start: 738680

End: 739636

Strand: Reverse

Name: fepB [H]

Synonym: ECUMN_0686

Alternate gene names: 218703927

Gene position: 739636-738680 (Counterclockwise)

Preceding gene: 218703935

Following gene: 218703925

Centisome position: 14.22

GC content: 55.38

Gene sequence:

>957_bases
GTGAGACTCGCCCCGCTCTACCGCAACGCCCTTCTATTAACAGGACTTTTGCTTTCAGGAATAGTCGCAGTTCAGGCCGC
CGACTGGCCGCGTCAGATTACTGACAGCCGGGGCACTCATACCCTGGAAAGCCAGCCGCAGCGTATTGTTTCCACCAGCG
TCACCCTGACCGGCTCACTGCTGGCGATTGATGCTCCGGTGATTGCCAGCGGCGCGACCACGCCGAATAACCGCGTCGCG
GATGACCAGGGCTTTTTACGCCAGTGGAGCAAGGTGGCGAAAGAACGCAAACTGCAACGGCTCTATATCGGCGAACCAAG
TGCAGAAGCCGTTGCCGCGCAAATGCCGGATCTGATTTTAATTAGCGCAACCGGCGGCGATTCGGCGCTGGCGCTGTACG
ATCAGCTTTCCACCATCGCCCCAACATTAATCATCAATTACGACGACAAAAGCTGGCAGTCGCTGTTAACGCAGCTTGGC
GAAATTACCGGGCATGAGAAACAAGCGGCAGAGCGGATTGCGCAGTTTGATAAGCAACTGGCGGCGGCGAAAGAGCAAAT
CAAATTACCTCCGCAGCCGGTCACTGCCATTGTCTATACCGCCGCTGCACACAGTGCTAATCTCTGGACGCCTGAATCAG
CACAAGGGCAGATGCTGGAACAACTCGGCTTTACGCTGGCGAAGTTGCCAGCAGGGTTAAACGCCAGCCAAAGCCAGGGC
AAACGCCATGACATCATTCAGCTTGGTGGGGAAAATCTGGCTTCAGGGTTAAATGGCGAGTCACTATTCCTGTTCGCCGG
TGATCAGAAAGATGCCGATGCGATTTATGCTAATCCGCTGCTCGCGCACCTGCCTGCAGTACAAAACAAGCAGGTTTATG
CGCTGGGAACCGAGACGTTCCGTCTGGATTACTACAGCGCCATGCAAGTGCTGGAACGGCTTAAGGCGCTGTTTTAA

Upstream 100 bases:

>100_bases
AACTCTTGAGGTAACGCAATCTGCAACTCGGGGTTGCATCTGGTTGTGGTTACAATGAAAATGAGAAGCATTAACTTCAT
TAATAACAGGAAGCTGACTT

Downstream 100 bases:

>100_bases
GCATTAACTGTCGGACGCTGTCACCTGCGGCGGCGTCTGGCGAAAACGCCGCAACTCCACCAGCACCAGCAATAACAACA
CGCCGATAATCAACAAACCA

Product: iron-enterobactin transporter periplasmic binding protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MRLAPLYRNALLLTGLLLSGIVAVQAADWPRQITDSRGTHTLESQPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVA
DDQGFLRQWSKVAKERKLQRLYIGEPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKSWQSLLTQLG
EITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLWTPESAQGQMLEQLGFTLAKLPAGLNASQSQG
KRHDIIQLGGENLASGLNGESLFLFAGDQKDADAIYANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQVLERLKALF

Sequences:

>Translated_318_residues
MRLAPLYRNALLLTGLLLSGIVAVQAADWPRQITDSRGTHTLESQPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVA
DDQGFLRQWSKVAKERKLQRLYIGEPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKSWQSLLTQLG
EITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLWTPESAQGQMLEQLGFTLAKLPAGLNASQSQG
KRHDIIQLGGENLASGLNGESLFLFAGDQKDADAIYANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQVLERLKALF
>Mature_318_residues
MRLAPLYRNALLLTGLLLSGIVAVQAADWPRQITDSRGTHTLESQPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVA
DDQGFLRQWSKVAKERKLQRLYIGEPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKSWQSLLTQLG
EITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLWTPESAQGQMLEQLGFTLAKLPAGLNASQSQG
KRHDIIQLGGENLASGLNGESLFLFAGDQKDADAIYANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQVLERLKALF

Specific function: Binds ferrienterobactin; part of the binding-protein- dependent transport system for uptake of ferrienterobactin [H]

COG id: COG4592

COG function: function code P; ABC-type Fe2+-enterobactin transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe/B12 periplasmic-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786807, Length=318, Percent_Identity=99.0566037735849, Blast_Score=636, Evalue=0.0,
Organism=Escherichia coli, GI87082411, Length=226, Percent_Identity=26.1061946902655, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002491 [H]

Pfam domain/function: PF01497 Peripla_BP_2 [H]

EC number: NA

Molecular weight: Translated: 34342; Mature: 34342

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50983 FE_B12_PBP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAPLYRNALLLTGLLLSGIVAVQAADWPRQITDSRGTHTLESQPQRIVSTSVTLTGSL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHCCCHHHHHHHHEEECCE
LAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQRLYIGEPSAEAVAAQMPDLIL
EEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEE
ISATGGDSALALYDQLSTIAPTLIINYDDKSWQSLLTQLGEITGHEKQAAERIAQFDKQL
EEECCCCCHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AAAKEQIKLPPQPVTAIVYTAAAHSANLWTPESAQGQMLEQLGFTLAKLPAGLNASQSQG
HHHHHHCCCCCCCHHHEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHCC
KRHDIIQLGGENLASGLNGESLFLFAGDQKDADAIYANPLLAHLPAVQNKQVYALGTETF
CCCHHHHCCCHHHHCCCCCCEEEEEECCCCCCCHHHHCHHHHHCCCCCCCEEEEECCCEE
RLDYYSAMQVLERLKALF
EHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLAPLYRNALLLTGLLLSGIVAVQAADWPRQITDSRGTHTLESQPQRIVSTSVTLTGSL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHCCCHHHHHHHHEEECCE
LAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQRLYIGEPSAEAVAAQMPDLIL
EEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEE
ISATGGDSALALYDQLSTIAPTLIINYDDKSWQSLLTQLGEITGHEKQAAERIAQFDKQL
EEECCCCCHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AAAKEQIKLPPQPVTAIVYTAAAHSANLWTPESAQGQMLEQLGFTLAKLPAGLNASQSQG
HHHHHHCCCCCCCHHHEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHCC
KRHDIIQLGGENLASGLNGESLFLFAGDQKDADAIYANPLLAHLPAVQNKQVYALGTETF
CCCHHHHCCCHHHHCCCCCCEEEEEECCCCCCCHHHHCHHHHHCCCCCCCEEEEECCCEE
RLDYYSAMQVLERLKALF
EHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]