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The map label for this gene is intD [H]

Identifier: 218703820

GI number: 218703820

Start: 644943

End: 646106

Strand: Reverse

Name: intD [H]

Synonym: ECUMN_0576

Alternate gene names: 218703820

Gene position: 646106-644943 (Counterclockwise)

Preceding gene: 218703821

Following gene: 218703819

Centisome position: 12.42

GC content: 47.08

Gene sequence:

>1164_bases
ATGTCACTCTTCCGCAGAAATGAAATATGGTATGCCTCGTATTCGCTCCCGGGCGGGAAACGAATTAAGGAATCTCTTGG
CACAAAGGACAAGCGGCAAGCTCAGGAGTTGCACGACAAGCGAAAAGCAGAACTCTGGCGAGTAGAAAAGCTAGGGGATT
TACCTGATGTCACTTTTGAAGAGGCCTGCCTAAGATGGCTTGAGGAAAAAGCTGATAAAAAATCTCTCGATTCAGATAAA
AGCCGGATTGAGTTCTGGCTTGAACATTTTGAGGGTATAAGGCTTAAAGATATCTCGGAGGCAAAGATTTACTCTGCTGT
AAGCAGAATGCATAACAGAAAGACGAAAGAAATATGGAAACAGAAAGTTCAGGCCGCCATCAGGAAAGGTAAAGAACTGC
CTGTTTATGAACCAAAGCCAGTATCAACTCAGACAAAGGCAAAGCATCTTGCCATGATAAAGGCCATTCTCCGTGCTGCA
GAACGCGACTGGAAGTGGCTGGAAAAAGCGCCTGTCATCAAGATACCAGCGGTCAGAAACAAGCGAGTCAGATGGCTGGA
AAAGGAGGAAGCAAAACGCCTTATTGATGAGTGCCCCGAACCACTGAAATCTGTCGTCAAGTTTGCGCTGGCAACTGGTC
TGAGAAAGTCGAACATCATAAATCTGGAATGGCAACAAATCGACATGCAGCGACGAGTTGCCTGGGTGAATCCAGAAGAG
AGCAAATCAAACCGCGCCATTGGTGTGGCGCTGAACGATACCGCCTGTAAAGTGTTGCGTGATCAAATAGGCAAGCATCA
CAAATGGGTGTTTGTACATACCAAGGCGGCTAAGCGAGCAGATGGAACATCAACGCCTGCGGTCAGGAAGATGCGCATCG
ACAGCAAGACATCATGGCTATCAGCTTGTCGTCGTGCAGGAATTGAAGATTTCCGTTTCCATGACCTCAGACACACCTGG
GCAAGCTGGCTGATTCAGTCAGGCGTCCCATTATCAGTGCTTCAGGAAATGGGCGGATGGGAGTCCATAGAAATGGTTCG
TAGGTATGCTCACCTTGCGCCTAATCATTTGACAGAGCATGCGAGGAAAATAGACGACATTTTTGGTGATAATGTCCCAA
ATATGTCCCACTCTGGAATTATGGAGGATATAAAGAAGGCGTAA

Upstream 100 bases:

>100_bases
CTCCTTACCTCACAACACGGCAAGCCTGCATTGCGGCGCTTCAGTCTCCGCTGCATACTGTCCAGGTGAGCGCGGGTGAT
GGCATAACAGAGGAAAGAAA

Downstream 100 bases:

>100_bases
CTGATTGAATTGTAATGGCGCGCCCTGCAGGATTCGAACCTGCGGCCCACGACTTAGAAGGTCGTTGCTCTATCCAACTG
AGCTAAGGGCGCGTTGATAC

Product: putative integrase; DLP12 prophage

Products: NA

Alternate protein names: Prophage QSR' integrase [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSLFRRNEIWYASYSLPGGKRIKESLGTKDKRQAQELHDKRKAELWRVEKLGDLPDVTFEEACLRWLEEKADKKSLDSDK
SRIEFWLEHFEGIRLKDISEAKIYSAVSRMHNRKTKEIWKQKVQAAIRKGKELPVYEPKPVSTQTKAKHLAMIKAILRAA
ERDWKWLEKAPVIKIPAVRNKRVRWLEKEEAKRLIDECPEPLKSVVKFALATGLRKSNIINLEWQQIDMQRRVAWVNPEE
SKSNRAIGVALNDTACKVLRDQIGKHHKWVFVHTKAAKRADGTSTPAVRKMRIDSKTSWLSACRRAGIEDFRFHDLRHTW
ASWLIQSGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEHARKIDDIFGDNVPNMSHSGIMEDIKKA

Sequences:

>Translated_387_residues
MSLFRRNEIWYASYSLPGGKRIKESLGTKDKRQAQELHDKRKAELWRVEKLGDLPDVTFEEACLRWLEEKADKKSLDSDK
SRIEFWLEHFEGIRLKDISEAKIYSAVSRMHNRKTKEIWKQKVQAAIRKGKELPVYEPKPVSTQTKAKHLAMIKAILRAA
ERDWKWLEKAPVIKIPAVRNKRVRWLEKEEAKRLIDECPEPLKSVVKFALATGLRKSNIINLEWQQIDMQRRVAWVNPEE
SKSNRAIGVALNDTACKVLRDQIGKHHKWVFVHTKAAKRADGTSTPAVRKMRIDSKTSWLSACRRAGIEDFRFHDLRHTW
ASWLIQSGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEHARKIDDIFGDNVPNMSHSGIMEDIKKA
>Mature_386_residues
SLFRRNEIWYASYSLPGGKRIKESLGTKDKRQAQELHDKRKAELWRVEKLGDLPDVTFEEACLRWLEEKADKKSLDSDKS
RIEFWLEHFEGIRLKDISEAKIYSAVSRMHNRKTKEIWKQKVQAAIRKGKELPVYEPKPVSTQTKAKHLAMIKAILRAAE
RDWKWLEKAPVIKIPAVRNKRVRWLEKEEAKRLIDECPEPLKSVVKFALATGLRKSNIINLEWQQIDMQRRVAWVNPEES
KSNRAIGVALNDTACKVLRDQIGKHHKWVFVHTKAAKRADGTSTPAVRKMRIDSKTSWLSACRRAGIEDFRFHDLRHTWA
SWLIQSGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEHARKIDDIFGDNVPNMSHSGIMEDIKKA

Specific function: Integrase from the cryptic lambdoic prophage DLP12. Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1786748, Length=387, Percent_Identity=99.7416020671835, Blast_Score=788, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 45019; Mature: 44887

Theoretical pI: Translated: 10.49; Mature: 10.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFRRNEIWYASYSLPGGKRIKESLGTKDKRQAQELHDKRKAELWRVEKLGDLPDVTFE
CCCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
EACLRWLEEKADKKSLDSDKSRIEFWLEHFEGIRLKDISEAKIYSAVSRMHNRKTKEIWK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHH
QKVQAAIRKGKELPVYEPKPVSTQTKAKHLAMIKAILRAAERDWKWLEKAPVIKIPAVRN
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCC
KRVRWLEKEEAKRLIDECPEPLKSVVKFALATGLRKSNIINLEWQQIDMQRRVAWVNPEE
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHEECCCCC
SKSNRAIGVALNDTACKVLRDQIGKHHKWVFVHTKAAKRADGTSTPAVRKMRIDSKTSWL
CCCCCEEEEEECHHHHHHHHHHCCCCCEEEEEECCHHHCCCCCCCCHHHHHHCCCHHHHH
SACRRAGIEDFRFHDLRHTWASWLIQSGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEH
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHCHHHHHHH
ARKIDDIFGDNVPNMSHSGIMEDIKKA
HHHHHHHHCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SLFRRNEIWYASYSLPGGKRIKESLGTKDKRQAQELHDKRKAELWRVEKLGDLPDVTFE
CCCCCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
EACLRWLEEKADKKSLDSDKSRIEFWLEHFEGIRLKDISEAKIYSAVSRMHNRKTKEIWK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHH
QKVQAAIRKGKELPVYEPKPVSTQTKAKHLAMIKAILRAAERDWKWLEKAPVIKIPAVRN
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCC
KRVRWLEKEEAKRLIDECPEPLKSVVKFALATGLRKSNIINLEWQQIDMQRRVAWVNPEE
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHEECCCCC
SKSNRAIGVALNDTACKVLRDQIGKHHKWVFVHTKAAKRADGTSTPAVRKMRIDSKTSWL
CCCCCEEEEEECHHHHHHHHHHCCCCCEEEEEECCHHHCCCCCCCCHHHHHHCCCHHHHH
SACRRAGIEDFRFHDLRHTWASWLIQSGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEH
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHHHHHHHCHHHHHHH
ARKIDDIFGDNVPNMSHSGIMEDIKKA
HHHHHHHHCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2553674; 2183007; 9278503 [H]