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The map label for this gene is fimA

Identifier: 218703013

GI number: 218703013

Start: 4990568

End: 4991116

Strand: Direct

Name: fimA

Synonym: ECIAI39_4787

Alternate gene names: 218703013

Gene position: 4990568-4991116 (Clockwise)

Preceding gene: 218703011

Following gene: 218703014

Centisome position: 97.24

GC content: 51.55

Gene sequence:

>549_bases
ATGAAAATTAAAACTCTGGCAATCGTTGTTCTGTCGGCTCTGTCCCTCAGTTCCGCAGCGGCTCTGGCCGATACTACGAC
GGTAAATGGTGGGACCGTTCACTTTAAAGGGGAAGTTGTTAACGCCGCTTGCGCAGTTGATGCAGGCTCTGTTGATCAAA
CCGTTCAGTTGGGACAGGTTCGTACCGCTAGCCTGAAGCAGGCTGGAGCAACCAGCTCTGCCGTTGGTTTTAACATTCAG
CTGAATGATTGCGATACCACTGTTGCCACAAAAGCCGCTGTTGCCTTCTTAGGTACGGCAATTGATGCTACGCGTACTGA
TGTACTGGCTCTGCTGAGTTCTGCTGCAGGTAGTGCAACAAACGTTGGCGTGCAGATCCTGGACAGAACAGGCAATGCTC
TGACGCTGGACGGTGCGACATTTAGTGCACAAACAACCCTGAATAACGGTACCAACACCATTCCGTTCCAGGCGCGTTAT
TATGCAATCGGCGAGGCAACCCCGGGTGCTGCTAATGCGGATGCGACCTTCAAGGTTCAGTATCAATAA

Upstream 100 bases:

>100_bases
AAAACTGTGCAGTGTTGGCAGTCAAACTCGTTGACAAAACAAAGTGTACAGAACGACTGCCCATGTCGATTTAGAAATAG
TTTTTTTAAAGGAAAGCAGC

Downstream 100 bases:

>100_bases
CCTACCCAGGTTCAGGGACGTCATTACGGGCAGGGATGCCCACCCTTGTGCGATAAAAATAACGATGAAAAGGAAGAGAT
TATTTCTATTAGCGTCGTTG

Product: major type 1 subunit fimbrin

Products: NA

Alternate protein names: Type-1A pilin [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKIKTLAIVVLSALSLSSAAALADTTTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLGQVRTASLKQAGATSSAVGFNIQ
LNDCDTTVATKAAVAFLGTAIDATRTDVLALLSSAAGSATNVGVQILDRTGNALTLDGATFSAQTTLNNGTNTIPFQARY
YAIGEATPGAANADATFKVQYQ

Sequences:

>Translated_182_residues
MKIKTLAIVVLSALSLSSAAALADTTTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLGQVRTASLKQAGATSSAVGFNIQ
LNDCDTTVATKAAVAFLGTAIDATRTDVLALLSSAAGSATNVGVQILDRTGNALTLDGATFSAQTTLNNGTNTIPFQARY
YAIGEATPGAANADATFKVQYQ
>Mature_182_residues
MKIKTLAIVVLSALSLSSAAALADTTTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLGQVRTASLKQAGATSSAVGFNIQ
LNDCDTTVATKAAVAFLGTAIDATRTDVLALLSSAAGSATNVGVQILDRTGNALTLDGATFSAQTTLNNGTNTIPFQARY
YAIGEATPGAANADATFKVQYQ

Specific function: Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family [H]

Homologues:

Organism=Escherichia coli, GI1790769, Length=182, Percent_Identity=90.6593406593407, Blast_Score=273, Evalue=3e-75,
Organism=Escherichia coli, GI87081753, Length=157, Percent_Identity=50.9554140127389, Blast_Score=123, Evalue=6e-30,
Organism=Escherichia coli, GI87082421, Length=183, Percent_Identity=34.4262295081967, Blast_Score=99, Evalue=1e-22,
Organism=Escherichia coli, GI87081804, Length=183, Percent_Identity=33.879781420765, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1789422, Length=161, Percent_Identity=36.6459627329193, Blast_Score=71, Evalue=4e-14,
Organism=Escherichia coli, GI1786746, Length=167, Percent_Identity=32.3353293413174, Blast_Score=70, Evalue=6e-14,
Organism=Escherichia coli, GI1786938, Length=188, Percent_Identity=30.8510638297872, Blast_Score=70, Evalue=7e-14,
Organism=Escherichia coli, GI1790773, Length=154, Percent_Identity=33.7662337662338, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966
- InterPro:   IPR000259
- InterPro:   IPR014779 [H]

Pfam domain/function: PF00419 Fimbrial [H]

EC number: NA

Molecular weight: Translated: 18317; Mature: 18317

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKTLAIVVLSALSLSSAAALADTTTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLGQV
CCCHHHHHHHHHHHCCCCCHHEECCEECCCCEEEEECEEEEEEEEECCCCCCCEEECCCE
RTASLKQAGATSSAVGFNIQLNDCDTTVATKAAVAFLGTAIDATRTDVLALLSSAAGSAT
EEHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
NVGVQILDRTGNALTLDGATFSAQTTLNNGTNTIPFQARYYAIGEATPGAANADATFKVQ
CCEEEEEECCCCEEEECCCEEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEE
YQ
EC
>Mature Secondary Structure
MKIKTLAIVVLSALSLSSAAALADTTTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLGQV
CCCHHHHHHHHHHHCCCCCHHEECCEECCCCEEEEECEEEEEEEEECCCCCCCEEECCCE
RTASLKQAGATSSAVGFNIQLNDCDTTVATKAAVAFLGTAIDATRTDVLALLSSAAGSAT
EEHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
NVGVQILDRTGNALTLDGATFSAQTTLNNGTNTIPFQARYYAIGEATPGAANADATFKVQ
CCEEEEEECCCCEEEECCCEEEEEEEECCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEE
YQ
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8636962; 11251843; 12657207 [H]