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The map label for this gene is yjhB

Identifier: 218702976

GI number: 218702976

Start: 4954772

End: 4955989

Strand: Direct

Name: yjhB

Synonym: ECIAI39_4747

Alternate gene names: 218702976

Gene position: 4954772-4955989 (Clockwise)

Preceding gene: 218702975

Following gene: 218702977

Centisome position: 96.55

GC content: 36.12

Gene sequence:

>1218_bases
ATGGCAACAGCATGGTATAAACAAGTTAATCCACCACAACGGAAAGCTCTTTTTTCCGCATGGCTTGGATATGTATTTGA
TGGCTTTGATTTTATGATGATATTTTACATTCTTCATATTATAAAAGCAGATCTTGGCATTACGGATATTCAGGCTACTT
TAATAGGGACAGTGGCCTTCATAGCCAGACCTATTGGAGGTGGTTTTTTTGGTGCCATGGCTGATAAATATGGTCGTAAG
CCAATGATGATGTGGGCAATTATCATTTACTCAGTCGGAACAGGCCTTAGCGGTATTGCTACAAACTTATATATGCTCGC
AGTTTGTCGTTTTATTGTTGGCTTAGGGATGTCTGGTGAATATGCATGTGCTTCAACTTATGCGGTAGAAAGTTGGCCTA
AAAATCTTCAATCTAAAGCTAGTGCTTTTTTGGTAAGTGGTTTTTCTGTTGGAAATATTATTGCGGCACAAATAATCCCT
CAGTTTGCTGAAGTATATGGATGGAGAAACTCTTTTTTTATAGGCCTGTTACCAGTTTTACTAGTTCTTTGGATCAGAAA
AAGTGCTCCAGAAAGTCAGGAGTGGATTGAAGATAAATATAAGGATAAATCAACTTTTTTGTCTGTCTTCAGAAAACCAC
ATCTTTCAATCTCTATGATCGTTTTCCTCGTCTGTTTTTGTCTATTTGGTGCAAACTGGCCGATAAACGGACTACTTCCT
TCCTACCTGGCAGATAATGGAGTTAATACAGTGGTTATTTCAACTCTGATGACAATAGCAGGTTTAGGAACACTGACAGG
TACAATATTTTTTGGTTTTGTTGGTGATAAGATTGGTGTAAAAAAAGCCTTTGTAGTCGGTCTAATAACTTCATTTGTTT
TCCTTTGTCCTCTTTTTTTTATTTCTGTGAAAAACTCTTCTCTTATAGGATTATGTCTCTTTGGATTAATGTTTACAAAT
TTAGGTATTGCAGGGTTGGTTCCAAAATTTATATATGATTACTTTCCAACAAAATTAAGAGGATTAGGGACCGGTCTTAT
TTATAACTTAGGGGCAACTGGAGGAATGGCCGCACCTGTATTAGCTACATACATTTCAGGATATTATGGCTTAGGTGTTT
CATTATTCATTGTTACGGTTGCATTCTCTGCCTTATTAATTTTGTTAGTTGGTTTTGATATTCCAGGTAAAATTTATAAA
CTATCCGTGGCTAAATAA

Upstream 100 bases:

>100_bases
GTACTGGCGTATTTGAAGACAATATAATTATTTCTGGATATTGTTGAGGCTCCCTAATATTTACTTTAAGGGCTATATTA
GAATAACACAGGAAACAAAT

Downstream 100 bases:

>100_bases
TTGGAGGCTTTATGATTAATTATGGCGTTGTTGGTGTTGGATACTTTGGCGCTGAATTAGCTCGTTTTATGAATATGCAT
GATAATGCAAAAATTACATG

Product: putative sialic acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MATAWYKQVNPPQRKALFSAWLGYVFDGFDFMMIFYILHIIKADLGITDIQATLIGTVAFIARPIGGGFFGAMADKYGRK
PMMMWAIIIYSVGTGLSGIATNLYMLAVCRFIVGLGMSGEYACASTYAVESWPKNLQSKASAFLVSGFSVGNIIAAQIIP
QFAEVYGWRNSFFIGLLPVLLVLWIRKSAPESQEWIEDKYKDKSTFLSVFRKPHLSISMIVFLVCFCLFGANWPINGLLP
SYLADNGVNTVVISTLMTIAGLGTLTGTIFFGFVGDKIGVKKAFVVGLITSFVFLCPLFFISVKNSSLIGLCLFGLMFTN
LGIAGLVPKFIYDYFPTKLRGLGTGLIYNLGATGGMAAPVLATYISGYYGLGVSLFIVTVAFSALLILLVGFDIPGKIYK
LSVAK

Sequences:

>Translated_405_residues
MATAWYKQVNPPQRKALFSAWLGYVFDGFDFMMIFYILHIIKADLGITDIQATLIGTVAFIARPIGGGFFGAMADKYGRK
PMMMWAIIIYSVGTGLSGIATNLYMLAVCRFIVGLGMSGEYACASTYAVESWPKNLQSKASAFLVSGFSVGNIIAAQIIP
QFAEVYGWRNSFFIGLLPVLLVLWIRKSAPESQEWIEDKYKDKSTFLSVFRKPHLSISMIVFLVCFCLFGANWPINGLLP
SYLADNGVNTVVISTLMTIAGLGTLTGTIFFGFVGDKIGVKKAFVVGLITSFVFLCPLFFISVKNSSLIGLCLFGLMFTN
LGIAGLVPKFIYDYFPTKLRGLGTGLIYNLGATGGMAAPVLATYISGYYGLGVSLFIVTVAFSALLILLVGFDIPGKIYK
LSVAK
>Mature_404_residues
ATAWYKQVNPPQRKALFSAWLGYVFDGFDFMMIFYILHIIKADLGITDIQATLIGTVAFIARPIGGGFFGAMADKYGRKP
MMMWAIIIYSVGTGLSGIATNLYMLAVCRFIVGLGMSGEYACASTYAVESWPKNLQSKASAFLVSGFSVGNIIAAQIIPQ
FAEVYGWRNSFFIGLLPVLLVLWIRKSAPESQEWIEDKYKDKSTFLSVFRKPHLSISMIVFLVCFCLFGANWPINGLLPS
YLADNGVNTVVISTLMTIAGLGTLTGTIFFGFVGDKIGVKKAFVVGLITSFVFLCPLFFISVKNSSLIGLCLFGLMFTNL
GIAGLVPKFIYDYFPTKLRGLGTGLIYNLGATGGMAAPVLATYISGYYGLGVSLFIVTVAFSALLILLVGFDIPGKIYKL
SVAK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082404, Length=405, Percent_Identity=99.5061728395062, Blast_Score=804, Evalue=0.0,
Organism=Escherichia coli, GI87082231, Length=452, Percent_Identity=34.9557522123894, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1788292, Length=399, Percent_Identity=24.3107769423559, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1790550, Length=389, Percent_Identity=24.9357326478149, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1789941, Length=434, Percent_Identity=25.1152073732719, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788942, Length=382, Percent_Identity=24.0837696335079, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787880, Length=176, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787291, Length=302, Percent_Identity=24.5033112582781, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87082320, Length=360, Percent_Identity=23.8888888888889, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322632, Length=367, Percent_Identity=23.7057220708447, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 44056; Mature: 43925

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC
>Mature Secondary Structure 
ATAWYKQVNPPQRKALFSAWLGYVFDGFDFMMIFYILHIIKADLGITDIQATLIGTVAF
CCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IARPIGGGFFGAMADKYGRKPMMMWAIIIYSVGTGLSGIATNLYMLAVCRFIVGLGMSGE
HHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
YACASTYAVESWPKNLQSKASAFLVSGFSVGNIIAAQIIPQFAEVYGWRNSFFIGLLPVL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
LVLWIRKSAPESQEWIEDKYKDKSTFLSVFRKPHLSISMIVFLVCFCLFGANWPINGLLP
HHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCH
SYLADNGVNTVVISTLMTIAGLGTLTGTIFFGFVGDKIGVKKAFVVGLITSFVFLCPLFF
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
ISVKNSSLIGLCLFGLMFTNLGIAGLVPKFIYDYFPTKLRGLGTGLIYNLGATGGMAAPV
HHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCCHHHEECCCCCCHHHHH
LATYISGYYGLGVSLFIVTVAFSALLILLVGFDIPGKIYKLSVAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]