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The map label for this gene is chpS

Identifier: 218702926

GI number: 218702926

Start: 4897358

End: 4897609

Strand: Direct

Name: chpS

Synonym: ECIAI39_4694

Alternate gene names: 218702926

Gene position: 4897358-4897609 (Clockwise)

Preceding gene: 218702925

Following gene: 218702927

Centisome position: 95.43

GC content: 50.0

Gene sequence:

>252_bases
ATGCGTATTACCATAAAAAGATGGGGGAACAGTTCAGGTATGGTCATTCCTAATGTTGTGATGAAAGAACTTAACTTACG
GCCGGGGCAGAGCGTGGAGGCGCAAGTGAGCAACAATCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCACGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Upstream 100 bases:

>100_bases
TTAACGCATAAAAAACTCTGCTGGCGTTCACAAATGCGCAGGGGTAAAACGTTTCCTGTAGCACCGTGAGTTATACTTTG
TATAACTTAAGGAGGTGCAG

Downstream 100 bases:

>100_bases
AGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGGTGCTGGT
CGACCTGCGCTTGTGCTCTC

Product: antitoxin ChpS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 83; Mature: 83

Protein sequence:

>83_residues
MRITIKRWGNSSGMVIPNVVMKELNLRPGQSVEAQVSNNQLILTPISRRYSLDELLAQCDMNATELSEQDVWGKSTPAGD
EIW

Sequences:

>Translated_83_residues
MRITIKRWGNSSGMVIPNVVMKELNLRPGQSVEAQVSNNQLILTPISRRYSLDELLAQCDMNATELSEQDVWGKSTPAGD
EIW
>Mature_83_residues
MRITIKRWGNSSGMVIPNVVMKELNLRPGQSVEAQVSNNQLILTPISRRYSLDELLAQCDMNATELSEQDVWGKSTPAGD
EIW

Specific function: Part of a toxin-antitoxin (TA) module. May be involved in the regulation of cell growth. It acts as a suppressor of the inhibitory function of ChpB protein. Both ChpS and ChpB probably bind to the promoter region of the chpSB operon to autoregulate their

COG id: COG2336

COG function: function code T; Growth regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PemI family [H]

Homologues:

Organism=Escherichia coli, GI87082393, Length=83, Percent_Identity=95.1807228915663, Blast_Score=166, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007159 [H]

Pfam domain/function: PF04014 SpoVT_AbrB [H]

EC number: NA

Molecular weight: Translated: 9332; Mature: 9332

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITIKRWGNSSGMVIPNVVMKELNLRPGQSVEAQVSNNQLILTPISRRYSLDELLAQCD
CEEEEEECCCCCCEEEHHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCHHHHHHHCC
MNATELSEQDVWGKSTPAGDEIW
CCCHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRITIKRWGNSSGMVIPNVVMKELNLRPGQSVEAQVSNNQLILTPISRRYSLDELLAQCD
CEEEEEECCCCCCEEEHHHHHHHCCCCCCCCEEEEECCCEEEEEECCCCCCHHHHHHHCC
MNATELSEQDVWGKSTPAGDEIW
CCCHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8226627; 3525538; 7610040; 9278503; 8083180 [H]