Click here to switch to the map view.

The map label for this gene is avtA

Identifier: 218702338

GI number: 218702338

Start: 4254728

End: 4255981

Strand: Direct

Name: avtA

Synonym: ECIAI39_4084

Alternate gene names: 218702338

Gene position: 4254728-4255981 (Clockwise)

Preceding gene: 218702337

Following gene: 218702341

Centisome position: 82.9

GC content: 52.07

Gene sequence:

>1254_bases
ATGACATTCTCCCTTTTTGGTGACAAATTTACCCGCCACTCCGGCATTACGCTGCTGATGGAAGATCTGAACGACGGTTT
ACGCACGCCTGGCGCGATTATGCTCGGCGGCGGTAATCCAGCGCAGATCCCGGAAATGCAGGACTACTTCCAGACGCTAC
TGACCGACATGCTGGAAAGTGGCAAAGCGACTGATGCACTGTGCAATTACGACGGTCCACAGGGGAAAACGGAGCTACTC
ACACTGCTTGCCGGAATGCTGCGCGAGAAGTTGGGTTGGGATATCGAACCACAGAATATTGCACTAACAAACGGCAGCCA
GAGCGCGTTTTTCTACTTATTTAATCTGTTTGCCGGACGCCGTGCCGATGGTCGGGTCAAAAAAGTGCTGTTCCCGCTGG
CACCTGAATATATTGGCTACGCTGACGCCGGACTGGAAGAAGATCTGTTTGTCTCTGCGCGTCCGAATATTGAACTGCTG
CCGGAAGGCCAGTTTAAATACCACGTCGATTTTGAGCATCTGCATATTGGCGAAGAAACCGGGATGATTTGCGTCTCCCG
GCCGACGAATCCAACAGGCAATGTGATTACTGACGAAGAGTTGCTGAAGCTTGACGCGCTGGCGAATCAACACGGCATTC
CGCTGGTGATTGATAACGCTTATGGCGTCCCGTTCCCGGGTATCATCTTCAGCGAAGCGCGCCCGCTGTGGAATCCGAAT
ATTGTACTGTGCATGAGTCTTTCCAAGCTGGGACTACCGGGTTCGCGCTGCGGCATTATCATCGCCAATGAAAAAATCAT
CACCGCAATCACCAACATGAACGGCATTATCAGCCTGGCGCCTGGCGGTATTGGTCCGGCGATAATGTGTGAAATGATTA
AGCGTAACGATCTGCTGCGCCTGTCTGAAACGGTTATCAAACCGTTTTATTACCAGCGTGTTCAGGAAACTATCGCCATC
ATTCGCCGCTATTTACCGGAAGATCGCTGCCTGATTCATAAACCGGAAGGAGCCATTTTCCTCTGGCTATGGTTTAAGGA
TTTGCCAATTACGACCGAGCAGCTCTACCAGCGCCTGAAAGCACGGGGCGTGCTGATGGTGCCGGGGCACAACTTCTTCC
CAGGGCTGGATAAACCGTGGCCACATACACATCAATGTATGCGCATGAACTACGTGCCGGAGCCGGATAAAATTGAGGCG
GGGGTGAAGATTCTGGCGGAAGAGATAGAAAGAGCCTGGGCTGAAAGCCATTAA

Upstream 100 bases:

>100_bases
GGATAAAGCACTGCTCCCTCTTCAACAGAGCGATTTGCACCCCAGCAAATGTAGCGTTATTGTTACCTTCCTTGCTACAG
AGTTCGACAGATATCCCGCT

Downstream 100 bases:

>100_bases
TACGCTATTCCGGCGTTGAGAAACGCCGGAAAAACGTTTCAAACAGGCTGCTGCCGTAGCCGATGCCGCTGCACTTTCTC
GACATCCATGCACTGCAACG

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIPEMQDYFQTLLTDMLESGKATDALCNYDGPQGKTELL
TLLAGMLREKLGWDIEPQNIALTNGSQSAFFYLFNLFAGRRADGRVKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELL
PEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLDALANQHGIPLVIDNAYGVPFPGIIFSEARPLWNPN
IVLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGIISLAPGGIGPAIMCEMIKRNDLLRLSETVIKPFYYQRVQETIAI
IRRYLPEDRCLIHKPEGAIFLWLWFKDLPITTEQLYQRLKARGVLMVPGHNFFPGLDKPWPHTHQCMRMNYVPEPDKIEA
GVKILAEEIERAWAESH

Sequences:

>Translated_417_residues
MTFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIPEMQDYFQTLLTDMLESGKATDALCNYDGPQGKTELL
TLLAGMLREKLGWDIEPQNIALTNGSQSAFFYLFNLFAGRRADGRVKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELL
PEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLDALANQHGIPLVIDNAYGVPFPGIIFSEARPLWNPN
IVLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGIISLAPGGIGPAIMCEMIKRNDLLRLSETVIKPFYYQRVQETIAI
IRRYLPEDRCLIHKPEGAIFLWLWFKDLPITTEQLYQRLKARGVLMVPGHNFFPGLDKPWPHTHQCMRMNYVPEPDKIEA
GVKILAEEIERAWAESH
>Mature_416_residues
TFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIPEMQDYFQTLLTDMLESGKATDALCNYDGPQGKTELLT
LLAGMLREKLGWDIEPQNIALTNGSQSAFFYLFNLFAGRRADGRVKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELLP
EGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLDALANQHGIPLVIDNAYGVPFPGIIFSEARPLWNPNI
VLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGIISLAPGGIGPAIMCEMIKRNDLLRLSETVIKPFYYQRVQETIAII
RRYLPEDRCLIHKPEGAIFLWLWFKDLPITTEQLYQRLKARGVLMVPGHNFFPGLDKPWPHTHQCMRMNYVPEPDKIEAG
VKILAEEIERAWAESH

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=417, Percent_Identity=99.0407673860911, Blast_Score=854, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 46682; Mature: 46551

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIPEMQDYFQTLLTDMLES
CEEECCCCCHHCCCCCEEEEEHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHC
GKATDALCNYDGPQGKTELLTLLAGMLREKLGWDIEPQNIALTNGSQSAFFYLFNLFAGR
CCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCC
RADGRVKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELLPEGQFKYHVDFEHLHIGEET
CCCCCHHHHHHHCCHHHCCCCCCCCCCCEEEECCCCEEEEECCCEEEEEEHHEEEECCCC
GMICVSRPTNPTGNVITDEELLKLDALANQHGIPLVIDNAYGVPFPGIIFSEARPLWNPN
CEEEEECCCCCCCCEECHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEECCCCCCCCCC
IVLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGIISLAPGGIGPAIMCEMIKRNDLLR
EEEEEEHHHCCCCCCCEEEEEECCEEEEEEECCCCEEEECCCCCCHHHHHHHHHCCCHHH
LSETVIKPFYYQRVQETIAIIRRYLPEDRCLIHKPEGAIFLWLWFKDLPITTEQLYQRLK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHH
ARGVLMVPGHNFFPGLDKPWPHTHQCMRMNYVPEPDKIEAGVKILAEEIERAWAESH
HCCEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIPEMQDYFQTLLTDMLES
EEECCCCCHHCCCCCEEEEEHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHC
GKATDALCNYDGPQGKTELLTLLAGMLREKLGWDIEPQNIALTNGSQSAFFYLFNLFAGR
CCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHCC
RADGRVKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELLPEGQFKYHVDFEHLHIGEET
CCCCCHHHHHHHCCHHHCCCCCCCCCCCEEEECCCCEEEEECCCEEEEEEHHEEEECCCC
GMICVSRPTNPTGNVITDEELLKLDALANQHGIPLVIDNAYGVPFPGIIFSEARPLWNPN
CEEEEECCCCCCCCEECHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEECCCCCCCCCC
IVLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGIISLAPGGIGPAIMCEMIKRNDLLR
EEEEEEHHHCCCCCCCEEEEEECCEEEEEEECCCCEEEECCCCCCHHHHHHHHHCCCHHH
LSETVIKPFYYQRVQETIAIIRRYLPEDRCLIHKPEGAIFLWLWFKDLPITTEQLYQRLK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHH
ARGVLMVPGHNFFPGLDKPWPHTHQCMRMNYVPEPDKIEAGVKILAEEIERAWAESH
HCCEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]