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The map label for this gene is arsR

Identifier: 218702256

GI number: 218702256

Start: 4150636

End: 4150989

Strand: Direct

Name: arsR

Synonym: ECIAI39_3993

Alternate gene names: 218702256

Gene position: 4150636-4150989 (Clockwise)

Preceding gene: 218702255

Following gene: 218702257

Centisome position: 80.88

GC content: 49.15

Gene sequence:

>354_bases
ATGTCATTTCTGTTACCCATCCAACTCTTCAAAATTCTTGCCGATGAAACCCGTTTGGGCATCGTTTTACTGCTCAGCGA
ACTGGGAGAGTTATGCGTCTGCGATCTGTGCACTGCCCTCGATCAGTCGCAGCCCAAGATCTCCCGCCATCTGGCATTAC
TGCGTGAAAGTGGGCTATTGCTGGACCGCAAGCAAGGAAAGTGGGTTCATTACCGTTTATCGCCGCATATTCCAGCATGG
GCGGCGAAAATTATTGAGCAGGCCTGGCGATGCGAACAGGAAAAGGTTCAGGTGATTGTCCGTAACCTCGCCAGACAAAA
TTGTTCCGCAGACAGTAAGAATATTTGTAGTTAA

Upstream 100 bases:

>100_bases
CTATTACCTTCCTCTGCACATACGAATTCGTTAAACCATATATGTTTTTGACTTATCCGCTTCGAAGAGAGACACTAAGT
GCAACAATCAGGAGCGCAAT

Downstream 100 bases:

>100_bases
AAAATTTATCTAAACACATATGAATATTCGAATGTGTTTTATCCAGGAGGCATGATGTTACTGGCAGGCGCTATTTTTGT
CCTGACCATCGTATTGGTTA

Product: DNA-binding transcriptional repressor ArsR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 117; Mature: 116

Protein sequence:

>117_residues
MSFLLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQPKISRHLALLRESGLLLDRKQGKWVHYRLSPHIPAW
AAKIIEQAWRCEQEKVQVIVRNLARQNCSADSKNICS

Sequences:

>Translated_117_residues
MSFLLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQPKISRHLALLRESGLLLDRKQGKWVHYRLSPHIPAW
AAKIIEQAWRCEQEKVQVIVRNLARQNCSADSKNICS
>Mature_116_residues
SFLLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQPKISRHLALLRESGLLLDRKQGKWVHYRLSPHIPAWA
AKIIEQAWRCEQEKVQVIVRNLARQNCSADSKNICS

Specific function: Transcriptional repressor for the arsEFG operon. ArsE is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsE is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arse

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=117, Percent_Identity=96.5811965811966, Blast_Score=231, Evalue=1e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13308; Mature: 13177

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
5.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQPKISRHLALLRESGLL
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCE
LDRKQGKWVHYRLSPHIPAWAAKIIEQAWRCEQEKVQVIVRNLARQNCSADSKNICS
EECCCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SFLLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQPKISRHLALLRESGLL
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCE
LDRKQGKWVHYRLSPHIPAWAAKIIEQAWRCEQEKVQVIVRNLARQNCSADSKNICS
EECCCCCEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721697; 8041620; 9278503 [H]