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The map label for this gene is argE

Identifier: 218701333

GI number: 218701333

Start: 3151108

End: 3152259

Strand: Direct

Name: argE

Synonym: ECIAI39_3032

Alternate gene names: 218701333

Gene position: 3151108-3152259 (Clockwise)

Preceding gene: 218701328

Following gene: 218701334

Centisome position: 61.4

GC content: 52.69

Gene sequence:

>1152_bases
ATGAAAAACAAATTACCGCCATTTATCGAGATTTACCGTGCTCTGATTGCCACACCTTCAATAAGCGCCACGGAAGAGGC
ACTCGATCAAAGCAATGCAGATTTAATCACTCTGCTGGCGGACTGGTTTAAAGATTTAGGCTTCAATGTGGAAGTGCAGC
CTGTGCCAGGAACTCGCAACAAATTTAATATGCTGGCAAGTACCGGACAGGGGGCTGGCGGTTTGTTGCTGGCGGGGCAT
ACCGATACGGTGCCATTTGATGACGGACGCTGGACGCGCGATCCGTTTACACTGACGGAGCATGACGGCAAGCTTTACGG
CTTAGGCACCGCCGACATGAAAGGCTTTTTTGCGTTTATCCTTGATGCGCTACGCGATGTCGACGTCACGAAGCTTGCAA
AACCGCTCTACATTCTGGCGACTGCCGATGAAGAAACCAGTATGGCCGGAGCGCGTTATTTTGCCGAAACTACCGCCCTG
CGCCCGGATTGCGCCATCATTGGCGAACCGACGTCACTACAACCGGTACGCGCACATAAAGGTCATATCTCTAACGCCAT
CCGTATTCAGGGCCAGTCGGGCCACTCCAGCGATCCAGCACGCGGAGTTAACGCTATCGAACTGATGCACGACGCCATCG
GGCATATTTTGCAATTGCGCGATAACCTGAAAGAACGTTATCACTACGAAGCGTTTACCGTGCCATACCCCACGCTCAAC
CTCGGGCATATTCACGGTGGCGACGCTTCTAACCGTATTTGTGCTTGCTGTGAGTTGCATATGGATATCCGTCCGCTGCC
GGGCATGACACTCAATGAACTTAATGGCCTACTCAACGACGCGCTGGCTCCGGTGAGCGAACGCTGGCCGGGTCGTCTGA
CGGTCGACGAGCTGCATCCGCCGATCCCTGGCTATGAATGCCCGCCAAATCATCAACTGGTTGAAGTGGTTGAGAAATTG
CTCGGAGCAAAGACCGAAGTGGTGAATTACTGTACCGAAGCACCGTTTATTCAGACGTTATGCCCGACGCTGGTTCTGGG
GCCTGGCTCAATTAATCAGGCTCATCAACCTGATGAATATCTGGAGACGAGGTTTATCAAGCCCACCCGCGAACTGATCA
CCCAGGTGATTCACCATTTTTGCTGGCATTAA

Upstream 100 bases:

>100_bases
CCTTACGGCTGGTGGGTTTTATTACGCTCAACGTTAGTGTATTTTTATTCATAAATACTGCATGAATATTGATACTATCA
TGACCAGAGGTGTGTCAACA

Downstream 100 bases:

>100_bases
AACGTAGGCCAAACAATGTCGGATGCGATGCTTGCGCATCTTATCCGACCTACACCTTTGGTGTTACTCGAGGCGATTTT
TTAACATTCCCATAAGTTAC

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASTGQGAGGLLLAGH
TDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTAL
RPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYEAFTVPYPTLN
LGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKL
LGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH

Sequences:

>Translated_383_residues
MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASTGQGAGGLLLAGH
TDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTAL
RPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYEAFTVPYPTLN
LGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKL
LGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH
>Mature_383_residues
MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASTGQGAGGLLLAGH
TDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTAL
RPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYEAFTVPYPTLN
LGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKL
LGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=383, Percent_Identity=99.4778067885117, Blast_Score=790, Evalue=0.0,
Organism=Escherichia coli, GI1789236, Length=373, Percent_Identity=26.8096514745308, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788816, Length=259, Percent_Identity=28.957528957529, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17551016, Length=384, Percent_Identity=25.2604166666667, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42279; Mature: 42279

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRN
CCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
KFNMLASTGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFI
HHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHH
LDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTALRPDCAIIGEPTSLQPVRAHK
HHHHHCCCHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHC
GHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYEAFTVPYPTLN
CCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCE
LGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHP
ECCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCEEHHHCCC
PIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEY
CCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHEECCCCCCCCCCCHHH
LETRFIKPTRELITQVIHHFCWH
HHHHCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRN
CCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCCCC
KFNMLASTGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFI
HHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHH
LDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTALRPDCAIIGEPTSLQPVRAHK
HHHHHCCCHHHHCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHC
GHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYEAFTVPYPTLN
CCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCE
LGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHP
ECCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCCCEEHHHCCC
PIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEY
CCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHEECCCCCCCCCCCHHH
LETRFIKPTRELITQVIHHFCWH
HHHHCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA