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The map label for this gene is aslB

Identifier: 218701289

GI number: 218701289

Start: 3097014

End: 3098249

Strand: Reverse

Name: aslB

Synonym: ECIAI39_2990

Alternate gene names: 218701289

Gene position: 3098249-3097014 (Counterclockwise)

Preceding gene: 218701290

Following gene: 218701283

Centisome position: 60.37

GC content: 50.65

Gene sequence:

>1236_bases
ATGCTGCAACAGGTTCCAACGCGTGCTTTTCATGTGATGGCGAAACCGAGCGGTTCCGATTGTAATCTGAACTGTGACTA
CTGTTTTTATCTCGAAAAACAATCCCTTTACCGCGAAAAGCCAGTCACGCATATGGACGATGACACGCTGGAAGCGTATG
TCCGTCACTATATCGCTGCCAGCGAAACCCAAAACGAAGTGGCTTTTACCTGGCAGGGCGGCGAACCAACGTTACTCGGG
CTGGATTTTTACCGCCGAGCCGTGGCGCTACAGGCGAAATATGGTGCTGGCAGGAAGATAAGTAACAGCTTCCAGACTAA
CGGCGTTCTGCTTGATGACGAATGGTGTGCATTTCTGGCAGATAATCATTTTCTTGTTGGGTTATCGCTGGATGGTCCGG
CTGAGATCCACAATCAATATCGCGTGACCAAAGGCGGCAGACCAACGCATAAGCTGGTGATGCGTGCCCTGACGCTCCTG
CAAAAACATCATGTCGACTATAACGTGCTGGTCTGCGTAAATCGCACCAGTGCGTTACAACCTTTGCAAATCTATGATTT
TCTGTGTGATGCAGGCGTTGAGTTTATCCAGTTTATTCCGGTGGTCGAGCGCCTGGCTGATGAAACGGCTGCTCATGCTG
GACTTAAGCTACATGCTCCCGGCGATATTCAGGGCGAACTGACGGAATGGTCGGTACGCCCCGATGAGTTCGGTGAATTT
TTGGTGGCGATATTCGACCACTGGATCAAACGCGACGTCGGCAAGATTTTCGTGATGAATATCGAATGGGCGTTTGCCAA
TTTTGTCGGTGCGCCAGGAGCGGTTTGCCATCATCAGCCAACCTGTGGGCGCTCGGTGATTGTTGAACACAACGGCGACG
TTTACGCCTGCGATCACTATGTTTATTCGCAATATCGACTGGGGAATATGCTTCAGCAGACAATTGCAGAAATGGTAGAT
TCCCCGCAACAGCAGGTGTTTGGTGAAGATAAATTTAAGCAGTTACCAGCGCAGTGTCGCAGTTGTAACGTGTTAAAAGC
ATGTTGGGGAGGCTGCCCGAAACACCGCTTTATGCTCGATGCCAGCGGCAAACCGGGGCTGAATTATTTGTGTGCCGGGT
ATCAGCGTTATTTCCGCCATCTACCGCCATATCTTAAAGCAATGGCTGATTTGCTGGCGCACGGTCGTCCGGCCAGCGAC
ATTATGCAGGCGCATTTGATGGTGGTGAATAAGTAG

Upstream 100 bases:

>100_bases
GTCACTTTCCCTTCGCAATAAACGCCCGTAATAACGCATTGCGCCACGGTATGATTTCGCCCTTAACTTATTGAAGGATG
ACTTCAGGCAAGGAGCGACC

Downstream 100 bases:

>100_bases
AAATCGGCGGCCGCCTGCGGTTGATTGCCGGATGCGGCGTGAACGCCTTATCCGGCCTACAATCCTTGCAAATTCAATAA
ATTGCAGCGTTCTGTAGGCT

Product: regulator of arylsulfatase activity

Products: NA

Alternate protein names: AnSME homolog [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYVRHYIAASETQNEVAFTWQGGEPTLLG
LDFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLADNHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
QKHHVDYNVLVCVNRTSALQPLQIYDFLCDAGVEFIQFIPVVERLADETAAHAGLKLHAPGDIQGELTEWSVRPDEFGEF
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHYVYSQYRLGNMLQQTIAEMVD
SPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASD
IMQAHLMVVNK

Sequences:

>Translated_411_residues
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYVRHYIAASETQNEVAFTWQGGEPTLLG
LDFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLADNHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
QKHHVDYNVLVCVNRTSALQPLQIYDFLCDAGVEFIQFIPVVERLADETAAHAGLKLHAPGDIQGELTEWSVRPDEFGEF
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHYVYSQYRLGNMLQQTIAEMVD
SPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASD
IMQAHLMVVNK
>Mature_411_residues
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYVRHYIAASETQNEVAFTWQGGEPTLLG
LDFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLADNHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
QKHHVDYNVLVCVNRTSALQPLQIYDFLCDAGVEFIQFIPVVERLADETAAHAGLKLHAPGDIQGELTEWSVRPDEFGEF
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHYVYSQYRLGNMLQQTIAEMVD
SPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASD
IMQAHLMVVNK

Specific function: Potential Positive Factor For The Regulation Of Arylsulfatase. [C]

COG id: COG0641

COG function: function code R; Arylsulfatase regulator (Fe-S oxidoreductase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family [H]

Homologues:

Organism=Escherichia coli, GI48994973, Length=411, Percent_Identity=95.6204379562044, Blast_Score=829, Evalue=0.0,
Organism=Escherichia coli, GI87081923, Length=392, Percent_Identity=40.0510204081633, Blast_Score=323, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 46407; Mature: 46407

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYVRHYIAA
CCCCCCCCCEEEEECCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHHHH
SETQNEVAFTWQGGEPTLLGLDFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLA
CCCCCCEEEEEECCCCEEECHHHHHHHHHEEECCCCCCCCCCCCCCCCEEECCCHHEEEE
DNHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLLQKHHVDYNVLVCVNRTSALQ
CCEEEEEEECCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
PLQIYDFLCDAGVEFIQFIPVVERLADETAAHAGLKLHAPGDIQGELTEWSVRPDEFGEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEECCCCHHHHHHH
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHY
HHHHHHHHHHHCCCEEEEEEEEHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEHHH
VYSQYRLGNMLQQTIAEMVDSPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLD
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEE
ASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASDIMQAHLMVVNK
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHEECC
>Mature Secondary Structure
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYVRHYIAA
CCCCCCCCCEEEEECCCCCCCCCCCCEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHHHH
SETQNEVAFTWQGGEPTLLGLDFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLA
CCCCCCEEEEEECCCCEEECHHHHHHHHHEEECCCCCCCCCCCCCCCCEEECCCHHEEEE
DNHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLLQKHHVDYNVLVCVNRTSALQ
CCEEEEEEECCCCHHHCCCEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
PLQIYDFLCDAGVEFIQFIPVVERLADETAAHAGLKLHAPGDIQGELTEWSVRPDEFGEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCEECCCCHHHHHHH
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHY
HHHHHHHHHHHCCCEEEEEEEEHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEHHH
VYSQYRLGNMLQQTIAEMVDSPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLD
HHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEE
ASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASDIMQAHLMVVNK
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503; 11222759 [H]