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The map label for this gene is ygcS

Identifier: 218701255

GI number: 218701255

Start: 3056247

End: 3057584

Strand: Reverse

Name: ygcS

Synonym: ECIAI39_2953

Alternate gene names: 218701255

Gene position: 3057584-3056247 (Counterclockwise)

Preceding gene: 218701256

Following gene: 218701254

Centisome position: 59.58

GC content: 54.19

Gene sequence:

>1338_bases
ATGAACACTTCACCGGTGCGAATGGATGATTTACCGCTTAACCGTTTTCACTGTCGAATTGCTGCGCTCACTTTCGGTGC
ACACCTGACCGACGGTTATGTTCTCGGCGTCATTGGTTACGCCATTATTCAGCTTACGCCCGCCATGCAACTGACGCCGT
TTATGGCGGGAATGATCGGCGGCTCGGCGTTACTTGGTTTGTTTCTTGGCAGCCTGGTTTTGGGGTGGATCTCCGACCAT
ATCGGGCGGCAAAAAATTTTCACCTTCAGTTTTATGCTGATTACGCTCGCTTCGTTCTTGCAATTTTTTGCCACCACGCC
AGAGCATCTTATTGGGCTGCGCATTTTGATCGGCATTGGTCTGGGAGGCGATTACTCAGTCGGTCACACCTTGCTGGCTG
AATTTTCCCCGCGCCGCCATCGCGGTATTTTACTGGGCGCATTCAGCGTGGTGTGGACCGTAGGCTATGTGTTGGCAAGT
ATTGCCGGACATCACTTTATTTCCGAAAACCCGGAGGCCTGGCGCTGGCTGCTGGCATCAGCGGCGTTACCAGCCTTGCT
GATTACGCTGCTACGTTGGGGCACGCCGGAATCGCCACGCTGGCTACTGCGCCAGGGACGTTTTGCTGAAGCTCACGCTA
TTGTGCATCGCTATTTGGGGCCACATGTTTTACTGGGCGATGAAGTGGCAGCGGCGACCCATAAACACATCAAAACCTTG
TTTTCTTCGCGCTACTGGCGACGCACGGCGTTTAACAGCGTCTTCTTTGTCTGCCTCGTAATCCCATGGTTTGTGATTTA
TACCTGGCTGCCGACCATCGCCCAGACTATTGGTCTGGAGGATGCGCTGACCGCCAGCCTGATGCTTAATGCGTTGTTAA
TTGTGGGCGCGCTGCTGGGATTAGTTCTGACGCACCTGCTGGCACATCGCAAGTTTTTGCTGGGAAGTTTTTTGCTGCTG
GCGGCAACGCTGGTAGTGATGGCCTGTTTGCCTTCCGGCAGTTCATTAACGCTGCTGCTTTTTGTTCTCTTCAGCACCAC
CATTTCGGCAGTCAGTAATCTGGTGGGCATTTTGCCTGCGGAAAGTTTTCCTACTGACATTCGCTCGCTGGGCGTCGGTT
TTGCCACCGCCATGAGTCGGTTGGGGGCGGCGGTAAGTACTGGCCTGCTGCCGTGGGTGCTGGCGCAGTGGGGAATGCAA
GCCACCTTATTGCTCCTGGCGGCAGTGTTGTTGGTTGGTTTTGTTGTGACCTGGCTATGGGCACCAGAAACCAAAGCACT
CCCGCTGGTGGCGGCGGGAAATGTAGGAGGTGCGAATGAACATTCTGTTAGCGTTTAA

Upstream 100 bases:

>100_bases
AAAATAATGTGTCAGGCAGCGTTCCGCGATGACGGTGCGTTGCCTTTTCGGCTTCTCAGGCGAGAAGCCGTTCTTATTAC
CGGACAATGAAGGGGTAAAG

Downstream 100 bases:

>100_bases
AGCCGAACCGGATGCCGGAATGCTGGCGGAAAAAGAGTGGCAGGCGGCGGCTCAGGGTAATATTGGACCAGATGTTTCGC
TACTGCGAAGTTTACTCGGT

Product: putative transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDH
IGRQKIFTFSFMLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLAS
IAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYLGPHVLLGDEVAAATHKHIKTL
FSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLL
AATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQ
ATLLLLAAVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV

Sequences:

>Translated_445_residues
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDH
IGRQKIFTFSFMLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLAS
IAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYLGPHVLLGDEVAAATHKHIKTL
FSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLL
AATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQ
ATLLLLAAVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>Mature_445_residues
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDH
IGRQKIFTFSFMLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLAS
IAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYLGPHVLLGDEVAAATHKHIKTL
FSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLL
AATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQ
ATLLLLAAVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI4507005, Length=392, Percent_Identity=26.530612244898, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI302148518, Length=365, Percent_Identity=24.9315068493151, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI4506999, Length=426, Percent_Identity=26.5258215962441, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI166197673, Length=365, Percent_Identity=28.4931506849315, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI24497490, Length=334, Percent_Identity=26.0479041916168, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI23510410, Length=357, Percent_Identity=24.3697478991597, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI24308167, Length=446, Percent_Identity=23.542600896861, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI296080721, Length=345, Percent_Identity=26.9565217391304, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI296080734, Length=345, Percent_Identity=26.9565217391304, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI296080719, Length=345, Percent_Identity=26.9565217391304, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI24497499, Length=345, Percent_Identity=26.9565217391304, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI7662270, Length=209, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI213021148, Length=415, Percent_Identity=24.8192771084337, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI8923870, Length=382, Percent_Identity=24.869109947644, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI90669191, Length=348, Percent_Identity=27.0114942528736, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI24497497, Length=348, Percent_Identity=27.0114942528736, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI21553331, Length=312, Percent_Identity=23.7179487179487, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI20070188, Length=380, Percent_Identity=25.7894736842105, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI24497476, Length=380, Percent_Identity=25.7894736842105, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI203098995, Length=197, Percent_Identity=27.4111675126904, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI166064021, Length=330, Percent_Identity=25.4545454545455, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI11415038, Length=384, Percent_Identity=23.9583333333333, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87082159, Length=445, Percent_Identity=98.6516853932584, Blast_Score=863, Evalue=0.0,
Organism=Escherichia coli, GI1786229, Length=437, Percent_Identity=34.324942791762, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1788074, Length=418, Percent_Identity=26.3157894736842, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788068, Length=451, Percent_Identity=24.390243902439, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1789207, Length=444, Percent_Identity=25.6756756756757, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789312, Length=436, Percent_Identity=24.5412844036697, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790463, Length=427, Percent_Identity=23.4192037470726, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87082404, Length=405, Percent_Identity=22.4691358024691, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082231, Length=416, Percent_Identity=24.0384615384615, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17556354, Length=408, Percent_Identity=27.2058823529412, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17565976, Length=165, Percent_Identity=30.3030303030303, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17560496, Length=390, Percent_Identity=23.8461538461538, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17564080, Length=407, Percent_Identity=24.8157248157248, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71988651, Length=156, Percent_Identity=35.2564102564103, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193209824, Length=395, Percent_Identity=24.8101265822785, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17565978, Length=327, Percent_Identity=24.4648318042813, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145172, Length=398, Percent_Identity=23.8693467336683, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320595, Length=183, Percent_Identity=32.2404371584699, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320766, Length=366, Percent_Identity=24.3169398907104, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6324400, Length=366, Percent_Identity=24.0437158469945, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322618, Length=366, Percent_Identity=23.7704918032787, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319956, Length=366, Percent_Identity=23.7704918032787, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI19922616, Length=394, Percent_Identity=25.3807106598985, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24649618, Length=339, Percent_Identity=26.2536873156342, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24649622, Length=387, Percent_Identity=24.2894056847545, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24668440, Length=406, Percent_Identity=24.1379310344828, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640198, Length=440, Percent_Identity=23.8636363636364, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640196, Length=440, Percent_Identity=23.8636363636364, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640200, Length=440, Percent_Identity=23.8636363636364, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24668456, Length=408, Percent_Identity=25, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI161078338, Length=399, Percent_Identity=26.0651629072682, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19922874, Length=405, Percent_Identity=24.9382716049383, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24649616, Length=359, Percent_Identity=25.6267409470752, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24647365, Length=330, Percent_Identity=25.7575757575758, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI161077756, Length=455, Percent_Identity=23.7362637362637, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24644778, Length=400, Percent_Identity=25.25, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 48103; Mature: 48103

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIG
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GSALLGLFLGSLVLGWISDHIGRQKIFTFSFMLITLASFLQFFATTPEHLIGLRILIGIG
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEC
LGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLAS
CCCCCHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHHHH
AALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYLGPHVLLGDEVAAATHKHIKTL
HHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHH
FSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
ESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQATLLLLAAVLLVGFVVTWLW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHC
APETKALPLVAAGNVGGANEHSVSV
CCCCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIG
CCCCCCCCCCCCCHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GSALLGLFLGSLVLGWISDHIGRQKIFTFSFMLITLASFLQFFATTPEHLIGLRILIGIG
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEC
LGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLAS
CCCCCHHHHHHHHHCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHHHH
AALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYLGPHVLLGDEVAAATHKHIKTL
HHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHH
FSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
LVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
ESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQATLLLLAAVLLVGFVVTWLW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHC
APETKALPLVAAGNVGGANEHSVSV
CCCCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]