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The map label for this gene is cysC

Identifier: 218701241

GI number: 218701241

Start: 3042519

End: 3043124

Strand: Reverse

Name: cysC

Synonym: ECIAI39_2939

Alternate gene names: 218701241

Gene position: 3043124-3042519 (Counterclockwise)

Preceding gene: 218701242

Following gene: 218701240

Centisome position: 59.3

GC content: 51.49

Gene sequence:

>606_bases
ATGGCGCTGCATGACGAAAACGTCGTCTGGCATAGCCACCCAGTAACTCCGCAACAACGCGAACAGCACCACGGTCATCG
TGGTGTTGTGCTGTGGTTTACCGGCCTCTCTGGTTCCGGTAAATCAACCGTCGCGGGGGCGCTGGAGGAGGCGTTACATA
AACTTGGCGTCAGTACGTATCTGCTGGATGGCGACAATGTTCGCCACGGATTATGCAGCGATCTCGGTTTTAGCGATGCC
GATCGTAAAGAAAATATCCGTCGCGTCGGTGAAGTGGCGAATTTGATGGTTGAAGCCGGACTGGTGGTGCTGACCGCATT
TATCTCGCCACACCGCGCCGAACGCCAGATGGTTCGCGAACGCGTAGGAGAAGGGCGCTTTATCGAAGTGTTTGTCGATA
CACCGCTGGCGATTTGCGAAGCCCGCGATCCAAAAGGCTTATATAAGAAAGCGCGTGCCGGTGAACTGCGCAACTTTACG
GGAATAGATTCCGTTTACGAAGCGCCTGAATCGGCAGAAATTCATCTCAATGGTGAACAATTAGTAACAAATTTGGTACA
GCAATTATTAGATCTGTTGAGACAGAACGATATTATCAGATCCTGA

Upstream 100 bases:

>100_bases
CTGCGCCATCTGAATTCAGTGCATTCGAACTGGAATTGAATGCCCTGGTTCGCCGCCATTTCCCGCATTGGGGTGCGCGC
GATTTACTGGGAGATAAATA

Downstream 100 bases:

>100_bases
GACACCACCGGGTTTCCATGCCCGGTTCGTCAAAGTAACAGGATCAAATATGCGTAATAGCCATAACATTACACTAACAA
ATAACGACAGCCTTACTGAG

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MALHDENVVWHSHPVTPQQREQHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDA
DRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFT
GIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS

Sequences:

>Translated_201_residues
MALHDENVVWHSHPVTPQQREQHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDA
DRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFT
GIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>Mature_200_residues
ALHDENVVWHSHPVTPQQREQHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDAD
RKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTG
IDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=201, Percent_Identity=51.7412935323383, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI34447231, Length=201, Percent_Identity=50.7462686567164, Blast_Score=193, Evalue=8e-50,
Organism=Homo sapiens, GI62912492, Length=201, Percent_Identity=50.7462686567164, Blast_Score=193, Evalue=9e-50,
Organism=Escherichia coli, GI1789107, Length=201, Percent_Identity=99.0049751243781, Blast_Score=405, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17542422, Length=201, Percent_Identity=51.2437810945274, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6322852, Length=197, Percent_Identity=47.7157360406091, Blast_Score=188, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24667040, Length=200, Percent_Identity=47, Blast_Score=176, Evalue=9e-45,
Organism=Drosophila melanogaster, GI24667032, Length=200, Percent_Identity=47, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24667028, Length=200, Percent_Identity=47, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24667036, Length=200, Percent_Identity=47, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI116007838, Length=200, Percent_Identity=47, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24667044, Length=200, Percent_Identity=47, Blast_Score=176, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 22335; Mature: 22203

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALHDENVVWHSHPVTPQQREQHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTY
CCCCCCCEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEE
LLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRE
EECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQ
HHCCCCEEEEEECCCHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEEECHHH
LVTNLVQQLLDLLRQNDIIRS
HHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ALHDENVVWHSHPVTPQQREQHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTY
CCCCCCEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEE
LLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRE
EECCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
RVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQ
HHCCCCEEEEEECCCHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEEECHHH
LVTNLVQQLLDLLRQNDIIRS
HHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA