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The map label for this gene is hypE

Identifier: 218701222

GI number: 218701222

Start: 3025121

End: 3026089

Strand: Direct

Name: hypE

Synonym: ECIAI39_2919

Alternate gene names: 218701222

Gene position: 3025121-3026089 (Clockwise)

Preceding gene: 218701221

Following gene: 218701223

Centisome position: 58.95

GC content: 57.89

Gene sequence:

>969_bases
ATGCAGCAATTAATCAACAGCCTGTTTATGGAAGCCTTTGCCAACCCGTGGCTGGCAGAGCAGGAAGATCAGGCCCGTCT
TGATCTGGCGCAGCTGGTAGCGGAAGGCGACCGTCTGGCGTTCTCCACCGACAGCTACGTCATCGACCCGCTGTTCTTTC
CTGGTGGCAATATCGGCAAGTTGGCGATTTGCGGCACCGCGAACGACGTAGCGGTCAGTGGCGCTATTCCGCGTTATCTC
TCCTGTGGATTTATCCTTGAAGAAGGATTACCGATGGAGACGCTGAAAGCCGTTGTGACCAGCATGGCAGAAACCGCCCG
CGCGGCAGGCATTGCCATCGTTACTGGCGACACTAAAGTGGTGCAGCGCGGCGCGGCAGATAAACTGTTTATCAACACCG
CTGGTATGGGCGCAATTCCGGCGAATATTCACTGGGGCGCACAGACGCTAACCGCAGGCGATGTTCTGCTGGTGAGTGGA
ACTCTCGGCGACCACGGGGCGACTATCCTTAACCTGCGTGAGCAACTGGGGCTGGATGGCGAACTGGTCAGCGACTGCGC
GGTGCTGACGCCGCTCATCCAGACGCTGCGTGATATTCCCGGTGTGAAGGCACTGCGTGACGCCACCCGTGGTGGAGTGA
ACGCGGTAGTTCATGAGTTCGCGGCAGCATGCGGTTGCGGTATTGAAATTTCAGAAGCGGCACTGCCGGTTAAACCTGCC
GTGCGCGGCGTTTGCGAACTGCTGGGGCTGGACGCCCTTAACTTTGCCAACGAAGGCAAACTGGTGATCGCCGTTGAACG
CAACGCAGCAGAGCAAGTGCTGGCGGCGTTACATTCCCATCCACTGGGGAAAGACGCGGCGCTGATTGGTGAAGTGGTGG
AACGTAAAGGTGTTCGTCTTGCCGGTCTGTATGGCGTGAAACGAACCCTCGATTTACCACACGCCGAACCGCTTCCGCGT
ATATGCTAA

Upstream 100 bases:

>100_bases
TTTCCTCCGAAGGAGCGTGCGCCGCGTGGTATCAGTATCGTCAGCAGGAGAGTGAAGCGTGAATAATATCCAACTCGCCC
ACGGTAGCGGCGGCCAGGCG

Downstream 100 bases:

>100_bases
TAAAATTCTAAATCTCCTATAGTTAGTCAATGACCTTTTGCACCGCTTTGCGGTGCTTTCCTGGAAGAACAAAATGTCAT
ATACACCGATGAGTGATCTC

Product: carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYL
SCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSG
TLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEISEAALPVKPA
VRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR
IC

Sequences:

>Translated_322_residues
MQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYL
SCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSG
TLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEISEAALPVKPA
VRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR
IC
>Mature_322_residues
MQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYL
SCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSG
TLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEISEAALPVKPA
VRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR
IC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=322, Percent_Identity=99.3788819875776, Blast_Score=644, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 33685; Mature: 33685

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGK
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCEEECEEECCCCCCCE
LAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKV
EEEECCCCCEEECCCCHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCHHH
VQRGAADKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDG
HHCCCCCEEEEEECCCCCCCCCEECCCCEECCCCEEEEECCCCCCCHHHHHHHHHHCCCH
ELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEISEAALPVKPA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCCCCCHH
VRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRL
HHHHHHHHCCHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEE
AGLYGVKRTLDLPHAEPLPRIC
EEEHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGK
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCEEECEEECCCCCCCE
LAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKV
EEEECCCCCEEECCCCHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCHHH
VQRGAADKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDG
HHCCCCCEEEEEECCCCCCCCCEECCCCEECCCCEEEEECCCCCCCHHHHHHHHHHCCCH
ELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIEISEAALPVKPA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCCCCCHH
VRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRL
HHHHHHHHCCHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEE
AGLYGVKRTLDLPHAEPLPRIC
EEEHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]