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The map label for this gene is gutQ

Identifier: 218701198

GI number: 218701198

Start: 3000265

End: 3001230

Strand: Direct

Name: gutQ

Synonym: ECIAI39_2894

Alternate gene names: 218701198

Gene position: 3000265-3001230 (Clockwise)

Preceding gene: 218701197

Following gene: 218701200

Centisome position: 58.46

GC content: 57.14

Gene sequence:

>966_bases
ATGAGTGAAGCACTACTGAACGCGGGACGTCAGACGTTAATGCTGGAGTTACAGGAAGCAAGCCGTTTACCGGAACGTCT
GGGCGATGATTTTGTTCGCGCCGCCAATATCATCCTGCACTGCGAAGGCAAAGTGGTGGTTTCGGGAATTGGCAAATCGG
GCCACATTGGTAAGAAAATCGCCGCAACGCTTGCCAGCACCGGCACTCCTGCCTTTTTTGTCCATCCGGCAGAGGCATTG
CACGGCGACCTGGGGATGATCGAAAGCCGCGATGTGATGCTGTTTATCTCTTACTCCGGTGGCGCGAAGGAACTGGATCT
GATTATTCCGCGTCTGGAAGATAAATCTATCGCGCTGCTGGCGATGACCGGCAAACCGACGTCACCGCTGGGCCTGGCGG
CGAAAGCGGTGCTGGATATCTCCGTAGAACGCGAAGCCTGCCCGATGCACCTTGCGCCGACCTCCAGCACCGTCAATACC
CTGATGATGGGTGACGCGCTGGCGATGGCGGTCATGCAGGCGCGCGGATTTAATGAAGAAGATTTTGCCCGCTCCCACCC
AGCCGGGGCACTGGGCGCTCGCTTGCTGAATAAAGTGCATCATCTGATGCGCCGTGATGACGCTATTCCGCAGGTAGCGT
TAACCGCCAGCGTGATGGATGCGATGCTGGAACTCAGCCGCACCGGTCTGGGGCTGGTGGCGGTATGTGACGCTCAGCAA
CAGGTACAAGGCGTCTTTACCGACGGTGATTTACGTCGCTGGCTGGTTGGCGGCGGCGCACTCACCACGCCAGTCAATGA
AGCGATGACGGTCGGCGGCACCACGTTGCAATCGCAAAGCCGTGCCATCGACGCCAAAGAAATCCTGATGAAACGCAAAA
TCACCGCCGCACCGGTAGTGGATGAAAACGGCAAACTCACCGGCGCAATTAACCTGCAGGATTTCTATCAGGCCGGGATT
ATTTAA

Upstream 100 bases:

>100_bases
GAAAGCGTCGATAAGCTAATTACCGACGCAGGTATCGATCCGGCGTTTCGTCAGGCGCTGGAAAAGAAAGGGATCGATGT
GATCATAACCGGAGAGAGCA

Downstream 100 bases:

>100_bases
TCCTTCAGCCCCAGACGTTTCGCCAACCGATGCAAGTTGGCGACGTCGGTTTCCAGCATCCGTGCGCTGGCAGCCCAGTT
GTGATGATTTTGTGCCTGTG

Product: D-arabinose 5-phosphate isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSEALLNAGRQTLMLELQEASRLPERLGDDFVRAANIILHCEGKVVVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEAL
HGDLGMIESRDVMLFISYSGGAKELDLIIPRLEDKSIALLAMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNT
LMMGDALAMAVMQARGFNEEDFARSHPAGALGARLLNKVHHLMRRDDAIPQVALTASVMDAMLELSRTGLGLVAVCDAQQ
QVQGVFTDGDLRRWLVGGGALTTPVNEAMTVGGTTLQSQSRAIDAKEILMKRKITAAPVVDENGKLTGAINLQDFYQAGI
I

Sequences:

>Translated_321_residues
MSEALLNAGRQTLMLELQEASRLPERLGDDFVRAANIILHCEGKVVVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEAL
HGDLGMIESRDVMLFISYSGGAKELDLIIPRLEDKSIALLAMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNT
LMMGDALAMAVMQARGFNEEDFARSHPAGALGARLLNKVHHLMRRDDAIPQVALTASVMDAMLELSRTGLGLVAVCDAQQ
QVQGVFTDGDLRRWLVGGGALTTPVNEAMTVGGTTLQSQSRAIDAKEILMKRKITAAPVVDENGKLTGAINLQDFYQAGI
I
>Mature_320_residues
SEALLNAGRQTLMLELQEASRLPERLGDDFVRAANIILHCEGKVVVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEALH
GDLGMIESRDVMLFISYSGGAKELDLIIPRLEDKSIALLAMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNTL
MMGDALAMAVMQARGFNEEDFARSHPAGALGARLLNKVHHLMRRDDAIPQVALTASVMDAMLELSRTGLGLVAVCDAQQQ
VQGVFTDGDLRRWLVGGGALTTPVNEAMTVGGTTLQSQSRAIDAKEILMKRKITAAPVVDENGKLTGAINLQDFYQAGII

Specific function: Not Known. [C]

COG id: COG0794

COG function: function code M; Predicted sugar phosphate isomerase involved in capsule formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain

Homologues:

Organism=Escherichia coli, GI87082151, Length=321, Percent_Identity=100, Blast_Score=651, Evalue=0.0,
Organism=Escherichia coli, GI1789588, Length=316, Percent_Identity=45.5696202531646, Blast_Score=282, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GUTQ_ECOLI (P17115)

Other databases:

- EMBL:   U29579
- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   X51361
- RefSeq:   AP_003275.1
- RefSeq:   NP_417188.4
- ProteinModelPortal:   P17115
- SMR:   P17115
- STRING:   P17115
- EnsemblBacteria:   EBESCT00000000995
- EnsemblBacteria:   EBESCT00000017893
- GeneID:   947587
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5431
- KEGG:   eco:b2708
- EchoBASE:   EB0966
- EcoGene:   EG10973
- eggNOG:   COG0794
- GeneTree:   EBGT00050000009485
- HOGENOM:   HBG754974
- OMA:   VHHLMRT
- ProtClustDB:   PRK11543
- BioCyc:   EcoCyc:EG10973-MONOMER
- BioCyc:   MetaCyc:EG10973-MONOMER
- Genevestigator:   P17115
- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR004800
- InterPro:   IPR001347
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00116
- TIGRFAMs:   TIGR00393

Pfam domain/function: PF00571 CBS; PF01380 SIS

EC number: NA

Molecular weight: Translated: 34032; Mature: 33901

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS51371 CBS; PS51464 SIS; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEALLNAGRQTLMLELQEASRLPERLGDDFVRAANIILHCEGKVVVSGIGKSGHIGKKI
CCCHHHHCCCHHEEEEHHHHHCCHHHHCHHHHHHCCEEEEECCEEEEEECCCCCCCHHHH
AATLASTGTPAFFVHPAEALHGDLGMIESRDVMLFISYSGGAKELDLIIPRLEDKSIALL
HHHHHCCCCCEEEECCHHHHCCCCCCEECCCEEEEEEECCCCCEEEEEEECCCCCCEEEE
AMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNTLMMGDALAMAVMQARGFNEE
EECCCCCCCHHHHHHHHEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHH
DFARSHPAGALGARLLNKVHHLMRRDDAIPQVALTASVMDAMLELSRTGLGLVAVCDAQQ
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCHH
QVQGVFTDGDLRRWLVGGGALTTPVNEAMTVGGTTLQSQSRAIDAKEILMKRKITAAPVV
HHCEECCCCCCEEEEECCCCCCCCCHHHEECCCCEECCHHHCCCHHHHHHHHCCCCCCEE
DENGKLTGAINLQDFYQAGII
CCCCCEEEEEEHHHHHHHCCC
>Mature Secondary Structure 
SEALLNAGRQTLMLELQEASRLPERLGDDFVRAANIILHCEGKVVVSGIGKSGHIGKKI
CCHHHHCCCHHEEEEHHHHHCCHHHHCHHHHHHCCEEEEECCEEEEEECCCCCCCHHHH
AATLASTGTPAFFVHPAEALHGDLGMIESRDVMLFISYSGGAKELDLIIPRLEDKSIALL
HHHHHCCCCCEEEECCHHHHCCCCCCEECCCEEEEEEECCCCCEEEEEEECCCCCCEEEE
AMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNTLMMGDALAMAVMQARGFNEE
EECCCCCCCHHHHHHHHEEEEECCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHH
DFARSHPAGALGARLLNKVHHLMRRDDAIPQVALTASVMDAMLELSRTGLGLVAVCDAQQ
HHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCHH
QVQGVFTDGDLRRWLVGGGALTTPVNEAMTVGGTTLQSQSRAIDAKEILMKRKITAAPVV
HHCEECCCCCCEEEEECCCCCCCCCHHHEECCCCEECCHHHCCCHHHHHHHHCCCCCCEE
DENGKLTGAINLQDFYQAGII
CCCCCEEEEEEHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 2134185