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The map label for this gene is appB

Identifier: 218700501

GI number: 218700501

Start: 2214075

End: 2215211

Strand: Reverse

Name: appB

Synonym: ECIAI39_2167

Alternate gene names: 218700501

Gene position: 2215211-2214075 (Counterclockwise)

Preceding gene: 218700502

Following gene: 218700500

Centisome position: 43.16

GC content: 53.39

Gene sequence:

>1137_bases
ATGTTTGATTATGAAACATTGCGCTTCATCTGGTGGCTGCTGATTGGCGTGATCCTGGTGGTCTTTATGATCTCCGACGG
ATTTGACATGGGGAGCGGCTGTCTGCTGCCGCTGGTGGCGCGTAATGATGATGAACGTCGGATAGTGATAAACAGCGTTG
GCGCGCACTGGGAAGGCAATCAGGTCTGGTTGATCCTCGCAGGTGGGGCATTATTTGCCGCCTGGCCCAGAGTGTATGCA
GCGGCGTTTTCCGGCTTTTATGTGGCGATGATCCTGGTGCTGTGCTCGCTGTTCTTCCGCCCGCTGGCCTTTGATTATCG
CGGAAAAATCGCCGATGCACGCTGGCGTAAAATGTGGGATGCCGGTTTGGTCATCGGCAGTCTGGTGCCGCCGGTAGTCT
TCGGTATCGCCTTCGGCAACTTGTTGCTCGGCGTGCCGTTTGCCTTCACACCGCAATTACGCGTGGAGTATCTCGGCAGC
TTCTGGCAACTGCTGACGCCATTCCCTTTATTGTGCGGATTGCTCAGCCTTGGGATGGTGATTTTGCAAGGTGGCGTCTG
GTTACAACTGAAAACTGTTGGTGTGATTCATCTGCGTTCACAGCTGGCGACTAAACGGGCTGCACTGTTGGTGATGCTGT
GCTTTTTGCTGGCGGGTTACTGGCTGTGGGTCGGTATTGATGGCTTTGTACTGCTCGCCCAGGATGCTAACGGTCCTTCC
AATCCGTTAATGAAACTGGTGGCAGTGCTACCTGGTGCCTGGATGAATAATTTTGTCGAATCGCCCGTTTTGTGGATCTT
CCCGCTGCTGGGGTTCTTCTGCCCATTGCTGACGGTGATGGCGATTTATCGTGGTCGCCCGGGTTGGGGATTTTTGATGG
CGTCATTGATGCAATTTGGCGTGATTTTCACGGCAGGCATCACGCTGTTCCCCTTTGTCATGCCGTCAAGCGTGAGTCCG
ATCTCCAGCCTGACGTTGTGGGACAGCACTTCCAGCCAGTTGACGCTGAGCATTATGTTGGTAATCGTGCTGATATTTTT
GCCCATTGTGTTGCTCTACACTCTCTGGAGCTACTACAAAATGTGGGGGCGCATGACAACAGAAACTCTCCGCCGTAACG
AAAACGAGCTGTACTAA

Upstream 100 bases:

>100_bases
TAATCGCCGAAGTCTACCTGATGCAGAAATATGCCCGTCTGGGGCCGAGCGCGATGCAGAGTGAACAACCGACGCAGCAA
CAGGGGTAAAGGAGAAAATC

Downstream 100 bases:

>100_bases
GGAGCAGGAACAATGTGGTATTTACTTTGGTTCGTCGGCATTTTGTTGATGTGTTCGCTCTCCACCCTTGTGTTGGTATG
GCTGGACCCGCAATTGAAAA

Product: cytochrome bd-II oxidase subunit II

Products: NA

Alternate protein names: Cytochrome bd-II oxidase subunit II [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MFDYETLRFIWWLLIGVILVVFMISDGFDMGSGCLLPLVARNDDERRIVINSVGAHWEGNQVWLILAGGALFAAWPRVYA
AAFSGFYVAMILVLCSLFFRPLAFDYRGKIADARWRKMWDAGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGS
FWQLLTPFPLLCGLLSLGMVILQGGVWLQLKTVGVIHLRSQLATKRAALLVMLCFLLAGYWLWVGIDGFVLLAQDANGPS
NPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPLLTVMAIYRGRPGWGFLMASLMQFGVIFTAGITLFPFVMPSSVSP
ISSLTLWDSTSSQLTLSIMLVIVLIFLPIVLLYTLWSYYKMWGRMTTETLRRNENELY

Sequences:

>Translated_378_residues
MFDYETLRFIWWLLIGVILVVFMISDGFDMGSGCLLPLVARNDDERRIVINSVGAHWEGNQVWLILAGGALFAAWPRVYA
AAFSGFYVAMILVLCSLFFRPLAFDYRGKIADARWRKMWDAGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGS
FWQLLTPFPLLCGLLSLGMVILQGGVWLQLKTVGVIHLRSQLATKRAALLVMLCFLLAGYWLWVGIDGFVLLAQDANGPS
NPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPLLTVMAIYRGRPGWGFLMASLMQFGVIFTAGITLFPFVMPSSVSP
ISSLTLWDSTSSQLTLSIMLVIVLIFLPIVLLYTLWSYYKMWGRMTTETLRRNENELY
>Mature_378_residues
MFDYETLRFIWWLLIGVILVVFMISDGFDMGSGCLLPLVARNDDERRIVINSVGAHWEGNQVWLILAGGALFAAWPRVYA
AAFSGFYVAMILVLCSLFFRPLAFDYRGKIADARWRKMWDAGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGS
FWQLLTPFPLLCGLLSLGMVILQGGVWLQLKTVGVIHLRSQLATKRAALLVMLCFLLAGYWLWVGIDGFVLLAQDANGPS
NPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPLLTVMAIYRGRPGWGFLMASLMQFGVIFTAGITLFPFVMPSSVSP
ISSLTLWDSTSSQLTLSIMLVIVLIFLPIVLLYTLWSYYKMWGRMTTETLRRNENELY

Specific function: Cytochrome oxidase subunit [H]

COG id: COG1294

COG function: function code C; Cytochrome bd-type quinol oxidase, subunit 2

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli CydB [H]

Homologues:

Organism=Escherichia coli, GI1787213, Length=378, Percent_Identity=99.7354497354497, Blast_Score=745, Evalue=0.0,
Organism=Escherichia coli, GI1786954, Length=379, Percent_Identity=57.5197889182058, Blast_Score=449, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003317 [H]

Pfam domain/function: PF02322 Cyto_ox_2 [H]

EC number: 1.10.3.-

Molecular weight: Translated: 42398; Mature: 42398

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDYETLRFIWWLLIGVILVVFMISDGFDMGSGCLLPLVARNDDERRIVINSVGAHWEGN
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCC
QVWLILAGGALFAAWPRVYAAAFSGFYVAMILVLCSLFFRPLAFDYRGKIADARWRKMWD
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGSFWQLLTPFPLLCGLLSLGMV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ILQGGVWLQLKTVGVIHLRSQLATKRAALLVMLCFLLAGYWLWVGIDGFVLLAQDANGPS
HHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
NPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPLLTVMAIYRGRPGWGFLMASLMQFG
HHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VIFTAGITLFPFVMPSSVSPISSLTLWDSTSSQLTLSIMLVIVLIFLPIVLLYTLWSYYK
HHHHHHHHHHHHHCCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MWGRMTTETLRRNENELY
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFDYETLRFIWWLLIGVILVVFMISDGFDMGSGCLLPLVARNDDERRIVINSVGAHWEGN
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCC
QVWLILAGGALFAAWPRVYAAAFSGFYVAMILVLCSLFFRPLAFDYRGKIADARWRKMWD
EEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGSFWQLLTPFPLLCGLLSLGMV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ILQGGVWLQLKTVGVIHLRSQLATKRAALLVMLCFLLAGYWLWVGIDGFVLLAQDANGPS
HHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
NPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPLLTVMAIYRGRPGWGFLMASLMQFG
HHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
VIFTAGITLFPFVMPSSVSPISSLTLWDSTSSQLTLSIMLVIVLIFLPIVLLYTLWSYYK
HHHHHHHHHHHHHCCCCCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MWGRMTTETLRRNENELY
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on diphenols and related substances as donors; With oxygen as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1658595; 8905232; 9278503; 8626304 [H]