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The map label for this gene is kch

Identifier: 218699957

GI number: 218699957

Start: 1658444

End: 1659697

Strand: Reverse

Name: kch

Synonym: ECIAI39_1586

Alternate gene names: 218699957

Gene position: 1659697-1658444 (Counterclockwise)

Preceding gene: 218699958

Following gene: 218699955

Centisome position: 32.34

GC content: 42.26

Gene sequence:

>1254_bases
GTGAGTCACTGGACTACATTCAAACAAACAGCAACAAAGTTATGGGTGACCCTACGGCACGACATTCTCGCGCTGGCCGT
CTTTTTAAATGGATTGCTTATTTTTAAAACAATCTATGGTATGTCGGTCAATTTGCTTGATATTTTCCATATCAAAGCAT
TTTCAGAGCTGGATCTCTCCTTGCTGGCAAACGCCCCACTATTTATGCTCGGCGTATTTCTTGTCCTGAACTCCATTGGC
TTACTGTTCCGGGCAAAGCTCGCATGGGCAATCAGTATCATTTTGTTGTTGATAGCGCTAATTTACACTCTGCATTTTTA
TCCCTGGCTGAAATTTAGTATTGGATTTTGCATTTTTACGCTGGTGTTTTTGCTGATACTGCGCAAAGACTTCTCCCACA
GTAGCGCAGCAGCCGGGACAATTTTCGCATTTATTAGTTTCACGACGTTACTGTTTTACTCCACTTACGGTGCGCTTTAT
TTAAGCGAAGGTTTTAATCCGCGAATAGAAAGTTTGATGACCGCGTTCTATTTTTCGATAGAAACCATGTCAACCGTCGG
CTATGGCGATATTGTCCCTGTTTCTGAATCAGCACGATTGTTCACTATTTCGGTCATTATTTCCGGCATTACCGTTTTTG
CCACATCTATGACCTCAATTTTTGGTCCGCTTATCCGCGGGGGATTCAACAAACTTGTAAAAGGAAACAATCATACAATG
CATCGTAAAGATCATTTTATTGTTTGCGGACATTCGATTCTCGCCATCAATACGATTCTGCAACTGAATCAACGCGGACA
AAACGTAACGGTTATCAGCAACTTGCCTGAAGATGATATCAAGCAACTTGAGCAACGCTTAGGCGATAACGCCGATGTTA
TCCCCGGTGACAGTAATGACAGTTCAGTGTTAAAGAAAGCGGGAATCGATCGTTGCCGGGCCATTCTGGCGCTGAGTGAT
AACGATGCAGATAACGCGTTTGTTGTACTCTCAGCAAAAGATATGAGCAGTGATGTCAAAACAGTTCTCGCCGTCAGTGA
TAGCAAAAACCTGAATAAGATTAAGATGGTACATCCGGATATCATTCTCTCACCACAACTGTTTGGCAGCGAAATTCTGG
CGCGAGTTTTAAATGGTGAAGAGATTAATAATGATATGCTCGTTTCAATGTTATTGAACTCCGGTCATGGCATTTTCAGC
GATAACGATGAACAAGAAACGAAAGCTGAAAGTAAAGAATCGGCGCAAAAATAG

Upstream 100 bases:

>100_bases
AAGTCATCTACTATTGTTTAACACATTCACGCGCTGCATGTATGTTCAGAAAATGTGCACGTTGAGATAATTAAACAAAA
TTGTGGTTACAGAGGTATCA

Downstream 100 bases:

>100_bases
AGTTTAAAGACGGAAAAGTAAACTTATTGGGCACCGCAATGGTGCCCAGAACATTTAGATATTGTAGATCGCAAACAATA
ACGAGTTACGCTGTTTGTTT

Product: voltage-gated potassium channel

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSHWTTFKQTATKLWVTLRHDILALAVFLNGLLIFKTIYGMSVNLLDIFHIKAFSELDLSLLANAPLFMLGVFLVLNSIG
LLFRAKLAWAISIILLLIALIYTLHFYPWLKFSIGFCIFTLVFLLILRKDFSHSSAAAGTIFAFISFTTLLFYSTYGALY
LSEGFNPRIESLMTAFYFSIETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMTSIFGPLIRGGFNKLVKGNNHTM
HRKDHFIVCGHSILAINTILQLNQRGQNVTVISNLPEDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSD
NDADNAFVVLSAKDMSSDVKTVLAVSDSKNLNKIKMVHPDIILSPQLFGSEILARVLNGEEINNDMLVSMLLNSGHGIFS
DNDEQETKAESKESAQK

Sequences:

>Translated_417_residues
MSHWTTFKQTATKLWVTLRHDILALAVFLNGLLIFKTIYGMSVNLLDIFHIKAFSELDLSLLANAPLFMLGVFLVLNSIG
LLFRAKLAWAISIILLLIALIYTLHFYPWLKFSIGFCIFTLVFLLILRKDFSHSSAAAGTIFAFISFTTLLFYSTYGALY
LSEGFNPRIESLMTAFYFSIETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMTSIFGPLIRGGFNKLVKGNNHTM
HRKDHFIVCGHSILAINTILQLNQRGQNVTVISNLPEDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSD
NDADNAFVVLSAKDMSSDVKTVLAVSDSKNLNKIKMVHPDIILSPQLFGSEILARVLNGEEINNDMLVSMLLNSGHGIFS
DNDEQETKAESKESAQK
>Mature_416_residues
SHWTTFKQTATKLWVTLRHDILALAVFLNGLLIFKTIYGMSVNLLDIFHIKAFSELDLSLLANAPLFMLGVFLVLNSIGL
LFRAKLAWAISIILLLIALIYTLHFYPWLKFSIGFCIFTLVFLLILRKDFSHSSAAAGTIFAFISFTTLLFYSTYGALYL
SEGFNPRIESLMTAFYFSIETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMTSIFGPLIRGGFNKLVKGNNHTMH
RKDHFIVCGHSILAINTILQLNQRGQNVTVISNLPEDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSDN
DADNAFVVLSAKDMSSDVKTVLAVSDSKNLNKIKMVHPDIILSPQLFGSEILARVLNGEEINNDMLVSMLLNSGHGIFSD
NDEQETKAESKESAQK

Specific function: May play a role in the defense against osmotic shock [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787503, Length=417, Percent_Identity=99.0407673860911, Blast_Score=833, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF07885 Ion_trans_2; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 46136; Mature: 46005

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHWTTFKQTATKLWVTLRHDILALAVFLNGLLIFKTIYGMSVNLLDIFHIKAFSELDLS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHH
LLANAPLFMLGVFLVLNSIGLLFRAKLAWAISIILLLIALIYTLHFYPWLKFSIGFCIFT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVFLLILRKDFSHSSAAAGTIFAFISFTTLLFYSTYGALYLSEGFNPRIESLMTAFYFSI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHH
ETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMTSIFGPLIRGGFNKLVKGNNHTM
HHHHHCCCCCEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
HRKDHFIVCGHSILAINTILQLNQRGQNVTVISNLPEDDIKQLEQRLGDNADVIPGDSND
ECCCCEEEECCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCH
SSVLKKAGIDRCRAILALSDNDADNAFVVLSAKDMSSDVKTVLAVSDSKNLNKIKMVHPD
HHHHHHHCHHHHHEEEEECCCCCCCEEEEEEECCCCCCHHEEEEECCCCCCCEEEEECCC
IILSPQLFGSEILARVLNGEEINNDMLVSMLLNSGHGIFSDNDEQETKAESKESAQK
EEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SHWTTFKQTATKLWVTLRHDILALAVFLNGLLIFKTIYGMSVNLLDIFHIKAFSELDLS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHH
LLANAPLFMLGVFLVLNSIGLLFRAKLAWAISIILLLIALIYTLHFYPWLKFSIGFCIFT
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVFLLILRKDFSHSSAAAGTIFAFISFTTLLFYSTYGALYLSEGFNPRIESLMTAFYFSI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHH
ETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMTSIFGPLIRGGFNKLVKGNNHTM
HHHHHCCCCCEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
HRKDHFIVCGHSILAINTILQLNQRGQNVTVISNLPEDDIKQLEQRLGDNADVIPGDSND
ECCCCEEEECCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCH
SSVLKKAGIDRCRAILALSDNDADNAFVVLSAKDMSSDVKTVLAVSDSKNLNKIKMVHPD
HHHHHHHCHHHHHEEEEECCCCCCCEEEEEEECCCCCCHHEEEEECCCCCCCEEEEECCC
IILSPQLFGSEILARVLNGEEINNDMLVSMLLNSGHGIFSDNDEQETKAESKESAQK
EEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8170937; 9097039; 9278503 [H]