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The map label for this gene is mdtJ

Identifier: 218699834

GI number: 218699834

Start: 1535004

End: 1535369

Strand: Direct

Name: mdtJ

Synonym: ECIAI39_1458

Alternate gene names: 218699834

Gene position: 1535004-1535369 (Clockwise)

Preceding gene: 218699832

Following gene: 218699835

Centisome position: 29.91

GC content: 42.08

Gene sequence:

>366_bases
ATGTATATTTATTGGATTTTATTAGGTCTGGCTATTGCTACAGAAATTACCGGTACGCTGTTTATGAAATGGGCGAGCGT
CAGTGAGGGAAATGGCGGCTTTATTTTAATGCTGGTGATGATTTCTCTGTCGTATATATTTCTCTCTTTCGCCGTTAAAA
AAATCGCCTTAGGCGTAGCTTATGCGCTGTGGGAAGGTATCGGTATTTTATTTATTACCTTGTTTAGCGTTTTGTTATTC
GACGAAAGTTTATCGCTGATGAAAATTGCCGGGTTAACCACCCTGGTGGCCGGGATTGTGTTGATCAAATCAGGTACCCG
TAAAGCGCATAAACCTGAACTGGAGGTGAACCATGGCGCAGTTTGA

Upstream 100 bases:

>100_bases
CTCCTGCTTAAGCTTGCGCTATGCGCGGGGCTTGACCACTTTACTTTGGTTTCGCTGAATTAAGCGAAAATTAAAATAAT
TCTCTTGCAGGAGAAGGACA

Downstream 100 bases:

>100_bases
ATGGGTTCACGCCGCCTGGCTGGCATTGGCAATCGTGCTGGAAATCGTTGCTAACGTCTTTTTGAAATTTTCTGACGGCT
TTCGTCGCAAAATATTTGGC

Product: multidrug efflux system protein MdtJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 121

Protein sequence:

>121_residues
MYIYWILLGLAIATEITGTLFMKWASVSEGNGGFILMLVMISLSYIFLSFAVKKIALGVAYALWEGIGILFITLFSVLLF
DESLSLMKIAGLTTLVAGIVLIKSGTRKAHKPELEVNHGAV

Sequences:

>Translated_121_residues
MYIYWILLGLAIATEITGTLFMKWASVSEGNGGFILMLVMISLSYIFLSFAVKKIALGVAYALWEGIGILFITLFSVLLF
DESLSLMKIAGLTTLVAGIVLIKSGTRKAHKPELEVNHGAV
>Mature_121_residues
MYIYWILLGLAIATEITGTLFMKWASVSEGNGGFILMLVMISLSYIFLSFAVKKIALGVAYALWEGIGILFITLFSVLLF
DESLSLMKIAGLTTLVAGIVLIKSGTRKAHKPELEVNHGAV

Specific function: Catalyzes the excretion of spermidine [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. MdtJ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787884, Length=121, Percent_Identity=98.3471074380165, Blast_Score=227, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 13156; Mature: 13156

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIYWILLGLAIATEITGTLFMKWASVSEGNGGFILMLVMISLSYIFLSFAVKKIALGVA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YALWEGIGILFITLFSVLLFDESLSLMKIAGLTTLVAGIVLIKSGTRKAHKPELEVNHGA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
V
C
>Mature Secondary Structure
MYIYWILLGLAIATEITGTLFMKWASVSEGNGGFILMLVMISLSYIFLSFAVKKIALGVA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YALWEGIGILFITLFSVLLFDESLSLMKIAGLTTLVAGIVLIKSGTRKAHKPELEVNHGA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
V
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA