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The map label for this gene is ydjJ

Identifier: 218699658

GI number: 218699658

Start: 1345128

End: 1346171

Strand: Direct

Name: ydjJ

Synonym: ECIAI39_1279

Alternate gene names: 218699658

Gene position: 1345128-1346171 (Clockwise)

Preceding gene: 218699657

Following gene: 218699659

Centisome position: 26.21

GC content: 46.36

Gene sequence:

>1044_bases
ATGAAAAATTCAAAAGCAATATTGCAGGTGCCGGGCACAATGAAAATTATTTCAGCAGAAATACCTGTGCCTAAAGAAGA
TGAAGTTTTGATTAAAGTAGAATATGTCGGTATTTGTGGTTCAGATGTACATGGTTTTGAATCAGGCCCGTTTATTCCGC
CTAAAGACCCAAATCAAGAAATTGGCCTGGGACATGAATGCGCCGGGACGGTTGTGGCTGTGGGAAGCCGTGTGCGCAAA
TTTAAAGCGGGGGATCGGGTAAATATCGAACCTGGCGTTCCTTGCGGTCACTGTCGTTACTGTCTGGAAGGCAAATATAA
CATCTGCCCGGACGTTGATTTTATGGCGACACAACCTAACTACCGCGGCGCATTAACGCACTATCTGTGTCATCCGGAGA
GCTTTACTTACAAACTGCCCGACAATATGGACACGATGGAAGGGGCGCTGGTGGAGCCTGCCGCAGTCGGGATGCATGCC
GCGATGCTGGCAGATGTTAAACCGGGTAAGAAGATAATTATTCTGGGAGCGGGTTGTATTGGTTTGATGACGTTGCAAGC
ATGCAAATGCCTGGGAGCTACGGATATTGCCGTCGTTGATGTACTGGAAAAACGTCTGACAATGGCGGAACAGCTCGGCG
CGACAGTGGTTATTAACGGCGCAAAAGAAGACACTATTGCACGCTGTCAGCAATTTACCGAAGAAATGGGCGCAGATATT
GTTTTCGAAACAGCGGGTTCTGCGGTCACCGTTAAACAGGCACCTTATCTGGTAATGCGCGGCGGTAAAATTATGATTGT
TGGTACTGTACCGGGCGATTCGGCAATCAATTTCCTCAAAATCAATCGCGAAGTCACTATCCAGACAGTATTCCGCTATG
CCAATCGTTATCCGGTCACGATTGAAGCTATTTCCTCAGGGCGATTCGATGTGAAATCGATGGTGACACATATTTACGAT
TATCAGGATGTACAACAGGCATTTGAAGAGTCGGTTAACAACAAACGCGACATTATTAAAGGCGTTATTAAAATTAGCGA
TTAA

Upstream 100 bases:

>100_bases
GCAATTGCTATCGCCACCATTGAAATTGAAACCAAAGGTGTCTCCGTTGAAAGTTTAAGTATTGATGCAGTAGTCAATAA
ATAATACTGGTGGATTCAAA

Downstream 100 bases:

>100_bases
TTAATACGGGAGAACAGAATATGCTCGCAGATATCAGATATTGGGAAAACGATGCCACAAATAAACATTATGCAATTGCC
CATTTTAACGTATGGAATGC

Product: putative iditol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKNSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRK
FKAGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHA
AMLADVKPGKKIIILGAGCIGLMTLQACKCLGATDIAVVDVLEKRLTMAEQLGATVVINGAKEDTIARCQQFTEEMGADI
VFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGDSAINFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYD
YQDVQQAFEESVNNKRDIIKGVIKISD

Sequences:

>Translated_347_residues
MKNSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRK
FKAGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHA
AMLADVKPGKKIIILGAGCIGLMTLQACKCLGATDIAVVDVLEKRLTMAEQLGATVVINGAKEDTIARCQQFTEEMGADI
VFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGDSAINFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYD
YQDVQQAFEESVNNKRDIIKGVIKISD
>Mature_347_residues
MKNSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRK
FKAGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHA
AMLADVKPGKKIIILGAGCIGLMTLQACKCLGATDIAVVDVLEKRLTMAEQLGATVVINGAKEDTIARCQQFTEEMGADI
VFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGDSAINFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYD
YQDVQQAFEESVNNKRDIIKGVIKISD

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=333, Percent_Identity=37.8378378378378, Blast_Score=221, Evalue=9e-58,
Organism=Homo sapiens, GI4501929, Length=355, Percent_Identity=26.1971830985915, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI34577061, Length=354, Percent_Identity=25.9887005649718, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4501933, Length=358, Percent_Identity=26.536312849162, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI71565154, Length=366, Percent_Identity=25.9562841530055, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI156523966, Length=361, Percent_Identity=26.8698060941828, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4501939, Length=361, Percent_Identity=26.8698060941828, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI71743840, Length=340, Percent_Identity=25.5882352941176, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI262073058, Length=340, Percent_Identity=25.5882352941176, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI194239674, Length=252, Percent_Identity=25.3968253968254, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI13236495, Length=252, Percent_Identity=25.3968253968254, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788073, Length=347, Percent_Identity=98.5590778097983, Blast_Score=704, Evalue=0.0,
Organism=Escherichia coli, GI1790045, Length=329, Percent_Identity=29.483282674772, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1788407, Length=336, Percent_Identity=29.4642857142857, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1787863, Length=345, Percent_Identity=27.2463768115942, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788075, Length=339, Percent_Identity=28.3185840707965, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1790718, Length=308, Percent_Identity=29.5454545454545, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI226510992, Length=343, Percent_Identity=28.5714285714286, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI87082125, Length=269, Percent_Identity=30.4832713754647, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786552, Length=367, Percent_Identity=27.7929155313352, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI87081918, Length=259, Percent_Identity=29.7297297297297, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17562876, Length=349, Percent_Identity=36.1031518624642, Blast_Score=225, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17562878, Length=345, Percent_Identity=36.5217391304348, Blast_Score=201, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI71988145, Length=260, Percent_Identity=30.3846153846154, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17562584, Length=273, Percent_Identity=30.03663003663, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI25146526, Length=367, Percent_Identity=22.3433242506812, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562582, Length=274, Percent_Identity=25.9124087591241, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323099, Length=350, Percent_Identity=36.8571428571429, Blast_Score=213, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6322619, Length=352, Percent_Identity=34.6590909090909, Blast_Score=198, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6319955, Length=352, Percent_Identity=34.6590909090909, Blast_Score=197, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6319257, Length=353, Percent_Identity=30.5949008498584, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6319258, Length=361, Percent_Identity=27.4238227146814, Blast_Score=119, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6320033, Length=366, Percent_Identity=26.775956284153, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323729, Length=298, Percent_Identity=26.8456375838926, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319621, Length=334, Percent_Identity=27.8443113772455, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324486, Length=289, Percent_Identity=26.643598615917, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6323961, Length=309, Percent_Identity=26.8608414239482, Blast_Score=86, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17137530, Length=350, Percent_Identity=39.1428571428571, Blast_Score=224, Evalue=5e-59,
Organism=Drosophila melanogaster, GI17737897, Length=353, Percent_Identity=38.2436260623229, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI221457811, Length=327, Percent_Identity=26.605504587156, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI45550770, Length=327, Percent_Identity=26.605504587156, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI45551930, Length=327, Percent_Identity=26.605504587156, Blast_Score=117, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 37677; Mature: 37677

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00059 ADH_ZINC ; PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQE
CCCCCEEEECCCCEEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
IGLGHECAGTVVAVGSRVRKFKAGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPN
CCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHEECCCCCCCCCCCEEECCCC
YRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHAAMLADVKPGKKIIILGAGCI
CCCCCEEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHEECCCCCEEEEEECCHH
GLMTLQACKCLGATDIAVVDVLEKRLTMAEQLGATVVINGAKEDTIARCQQFTEEMGADI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCE
VFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGDSAINFLKINREVTIQTVFRYANRYPVT
EEECCCCEEEEECCCEEEEECCEEEEEEECCCCCCEEEEEECCEEEHHHHHHHHCCCCEE
IEAISSGRFDVKSMVTHIYDYQDVQQAFEESVNNKRDIIKGVIKISD
EEEECCCCCCHHHHHHHHHCHHHHHHHHHHHCCCHHHHHEEEEEECC
>Mature Secondary Structure
MKNSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQE
CCCCCEEEECCCCEEEEEECCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCC
IGLGHECAGTVVAVGSRVRKFKAGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPN
CCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHEECCCCCCCCCCCEEECCCC
YRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHAAMLADVKPGKKIIILGAGCI
CCCCCEEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHEECCCCCEEEEEECCHH
GLMTLQACKCLGATDIAVVDVLEKRLTMAEQLGATVVINGAKEDTIARCQQFTEEMGADI
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCE
VFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGDSAINFLKINREVTIQTVFRYANRYPVT
EEECCCCEEEEECCCEEEEECCEEEEEEECCCCCCEEEEEECCEEEHHHHHHHHCCCCEE
IEAISSGRFDVKSMVTHIYDYQDVQQAFEESVNNKRDIIKGVIKISD
EEEECCCCCCHHHHHHHHHCHHHHHHHHHHHCCCHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]