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The map label for this gene is araH

Identifier: 218699535

GI number: 218699535

Start: 1223335

End: 1224324

Strand: Direct

Name: araH

Synonym: ECIAI39_1154

Alternate gene names: 218699535

Gene position: 1223335-1224324 (Clockwise)

Preceding gene: 218699534

Following gene: 218699536

Centisome position: 23.84

GC content: 50.61

Gene sequence:

>990_bases
ATGATGTCTTCTGTTTCTACATCGGGGTCTGGCGCACCTAAGTCGTCATTCAGCTTCGGGCGTATCTGGGATCAGTACGG
CATGCTGGTGGTGTTTGCGGTCCTTTTTATCGCCTGTGCCATTTTTGTCCCAAATTTTGCCACCTTCATTAATATGAAAG
GGTTGGGCCTGGCAATTTCCATGTCGGGGATGGTGGCGTGTGGCATGTTGTTCTGCCTTGCTTCCGGTGACTTTGACCTT
TCTGTCGCCTCCGTAATTGCCTGTGCGGGTGTCACCACGGCGGTGGTTATCAACCTGACTGAAAGCCTGTGGATTGGCGT
GGCAGCGGGGTTGCTGCTTGGCATTCTCTGTGGCCTGGTCAATGGCTTTGTTATCGCCAAACTGAAAATAAATGCTCTGA
TCACGACACTGGCAACGATGCAGATTGTTCGAGGTCTGGCGTACATCATTTCAGACGGTAAAGCGGTCGGTATCGAAGAT
GAAAGCTTCTTTGCCCTTGGTTACGCCAACTGGTTCGGTCTGCCTGCGCCAATCTGGCTTACCGTCGCGTGTCTGATTGT
CTTTGGTTTGCTGTTGAATAAAACCACCTTTGGTCGTAATACCCTGGCGATTGGCGGGAACGAAGAGGCTGCGCGTCTGG
CGGGTGTACCGGTTGTTCGCACCAAAATTATTATCTTTGTTCTCTCTGGCCTGGTATCAGCGATAGCCGGAATTATTCTG
GCTTCACGTATGACCAGTGGGCAGCCAATGACGTCGATTGGCTATGAGCTGATTGTTATCTCCGCCTGCGTTTTAGGTGG
CGTTTCTCTGAAAGGCGGCATCGGAAAAATCTCATATGTGGTGGCGGGTATCTTAATTTTAGGCACCGTGGAAAACGCCA
TGAACCTGCTTAATATTTCTCCTTTCGCACAGTACGTAGTTCGCGGCTTAATCTTGCTGGCAGCGGTGATTTTCGACCGT
TACAAGCAAAAAGCGAAACGCACTGTCTGA

Upstream 100 bases:

>100_bases
AAATCGCCGGTGAATTGTTACACGAGCAGGCAGATGAGCGTCAGGCACTGAGTCTTGCGATGCCTAAAGTCAGCCAGGCT
GTTGCCTGAGTAAGGAGAGT

Downstream 100 bases:

>100_bases
TGCTTTTTTCTACAACAATTTAGCGTTTTTTCCCACCACAGCCAGCCGCCACAACGGTTGGCTGTTCTTCGTTGCAAATG
GCGACCCCCGTCACACTGTC

Product: L-arabinose transporter permease

Products: ADP; phosphate; arabinose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MMSSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPNFATFINMKGLGLAISMSGMVACGMLFCLASGDFDL
SVASVIACAGVTTAVVINLTESLWIGVAAGLLLGILCGLVNGFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIED
ESFFALGYANWFGLPAPIWLTVACLIVFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLSGLVSAIAGIIL
ASRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKISYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDR
YKQKAKRTV

Sequences:

>Translated_329_residues
MMSSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPNFATFINMKGLGLAISMSGMVACGMLFCLASGDFDL
SVASVIACAGVTTAVVINLTESLWIGVAAGLLLGILCGLVNGFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIED
ESFFALGYANWFGLPAPIWLTVACLIVFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLSGLVSAIAGIIL
ASRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKISYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDR
YKQKAKRTV
>Mature_329_residues
MMSSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPNFATFINMKGLGLAISMSGMVACGMLFCLASGDFDL
SVASVIACAGVTTAVVINLTESLWIGVAAGLLLGILCGLVNGFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIED
ESFFALGYANWFGLPAPIWLTVACLIVFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLSGLVSAIAGIIL
ASRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKISYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDR
YKQKAKRTV

Specific function: Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693152, Length=328, Percent_Identity=99.390243902439, Blast_Score=639, Evalue=0.0,
Organism=Escherichia coli, GI1790191, Length=310, Percent_Identity=35.8064516129032, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1790524, Length=318, Percent_Identity=29.874213836478, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788896, Length=311, Percent_Identity=31.8327974276527, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789992, Length=343, Percent_Identity=31.7784256559767, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87082395, Length=272, Percent_Identity=32.3529411764706, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787793, Length=256, Percent_Identity=35.15625, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693214, Length=242, Percent_Identity=38.4297520661157, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787794, Length=274, Percent_Identity=29.1970802919708, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788471, Length=321, Percent_Identity=30.8411214953271, Blast_Score=92, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 34343; Mature: 34343

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPNFATFINMKGLGLAIS
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEE
MSGMVACGMLFCLASGDFDLSVASVIACAGVTTAVVINLTESLWIGVAAGLLLGILCGLV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NGFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIEDESFFALGYANWFGLPAPIWL
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEHHHCCCCHHHHH
TVACLIVFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLSGLVSAIAGIIL
HHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
ASRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKISYVVAGILILGTVENAMNLLNIS
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PFAQYVVRGLILLAAVIFDRYKQKAKRTV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMSSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPNFATFINMKGLGLAIS
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEE
MSGMVACGMLFCLASGDFDLSVASVIACAGVTTAVVINLTESLWIGVAAGLLLGILCGLV
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NGFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIEDESFFALGYANWFGLPAPIWL
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEHHHCCCCHHHHH
TVACLIVFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLSGLVSAIAGIIL
HHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
ASRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKISYVVAGILILGTVENAMNLLNIS
HHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
PFAQYVVRGLILLAAVIFDRYKQKAKRTV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; arabinose [Periplasm]; H2O [C]

Specific reaction: ATP + arabinose [Periplasm] + H2O = ADP + phosphate + arabinose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2445996; 9097040; 9278503; 8045430 [H]