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The map label for this gene is fliI

Identifier: 218699498

GI number: 218699498

Start: 1188810

End: 1190183

Strand: Reverse

Name: fliI

Synonym: ECIAI39_1115

Alternate gene names: 218699498

Gene position: 1190183-1188810 (Counterclockwise)

Preceding gene: 218699499

Following gene: 218699497

Centisome position: 23.19

GC content: 58.01

Gene sequence:

>1374_bases
ATGACCACGCGCCTGACTCGCTGGCTAACCACGCTGGATAACTTTGAAGCCAAAATGGCGCAGTTGCCTGCGGTACGTCG
CTACGGGCGATTAACCCGCGCTACCGGGCTGGTGCTGGAAGCCACCGGATTACAATTGCCGCTCGGCGCAACCTGTGTCA
TTGAGCGCCAGAACGGCAGCGAAACGCACGAAGTAGAAAGCGAAGTCGTTGGCTTTAACGGTCAACGGCTGTTTTTAATG
CCGCTGGAGGAAGTGGAAGGTGTCCTGCCCGGCGCGCGTGTATATGCCAAAAACATTTCGGCAGAAGGGCTGCAAAGCGG
CAAGCAGTTGCCGCTCGGTCCGGCGTTATTAGGTCGTGTTCTGGACGGTAGCGGTAAACCGCTCGATGGCCTGCCCTTCC
CCGATACGACGGAAACCGGTGCGCTGATTACCCCGCCATTTAACCCGTTGCAACGTACACCGATTGAACATGTGCTGGAC
ACCGGCGTGCGCCCAATCAATGCCCTGCTTACCGTCGGACGCGGGCAGCGTATGGGGCTGTTTGCCGGGTCCGGCGTTGG
GAAAAGTGTGCTGCTGGGGATGATGGCACGTTACACCCGCGCCGATGTCATTGTCGTGGGTTTGATTGGTGAACGTGGGC
GCGAAGTAAAAGATTTTATTGAGAATATCCTCGGTGCCGAAGGACGTGCACGCTCAGTGGTGATTGCCGCTCCGGCGGAT
GTTTCTCCGCTCCTGCGAATGCAGGGTGCCGCCTATGCCACGCGCATTGCCGAAGATTTTCGCGATCGTGGTCAGCATGT
GTTGCTGATTATGGACTCCCTCACCCGCTACGCGATGGCCCTGCGTGAAATTGCGCTGGCGATTGGCGAACCACCTGCCA
CTAAAGGTTATCCACCGTCGGTGTTTGCCAAATTACCGGCACTGGTCGAGCGTGCCGGAAATGGTATTAGCGGCGGCGGC
TCGATTACCGCGTTTTATACCGTGCTCACCGAAGGCGATGACCAGCAGGACCCCATTGCTGACTCCGCGCGGGCAATCCT
CGACGGTCACATTGTGCTGTCTCGCCGACTGGCGGAAGCCGGGCACTATCCGGCTATCGATATTGAAGCGTCGATCAGTC
GCGCAATGACGGCGTTGATCAGTGAGCAACATTACGCGCGAGTGCGCACCTTCAAACAGCTGTTGTCGAGTTTTCAGCGT
AACCGCGATCTGGTTAGCGTCGGCGCGTATGCCAAAGGCAGCGATCCGATGCTCGACAAAGCCATCGCCCTGTGGCCGCA
GCTGGAGAGCTATTTGCAACAAGGCATTTTTGAACGCGCGGACTGGGAAGCGTCTCTCCAGGGGCTGGAGCGTATTTTCC
CGACAGTGTCATAA

Upstream 100 bases:

>100_bases
CTGGCGGCTGTAAAGTCTCCGCCGATGAAGGCGATCTCGACGCCAGTGTCGCCACCCGCTGGCAAGAACTCTGCCGTCTG
GCAGCACCAGGAGTGGTGTA

Downstream 100 bases:

>100_bases
CCCAGGAGATAACGGCAGATGGCGGAACATGGTGCGCTGGCGACCCTGAAAGATCTGGCAGAAAAAGAGGTAGAGGATGC
CGCTCGCCTGCTGGGTGAAA

Product: flagellum-specific ATP synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MTTRLTRWLTTLDNFEAKMAQLPAVRRYGRLTRATGLVLEATGLQLPLGATCVIERQNGSETHEVESEVVGFNGQRLFLM
PLEEVEGVLPGARVYAKNISAEGLQSGKQLPLGPALLGRVLDGSGKPLDGLPFPDTTETGALITPPFNPLQRTPIEHVLD
TGVRPINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKDFIENILGAEGRARSVVIAAPAD
VSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMALREIALAIGEPPATKGYPPSVFAKLPALVERAGNGISGGG
SITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALISEQHYARVRTFKQLLSSFQR
NRDLVSVGAYAKGSDPMLDKAIALWPQLESYLQQGIFERADWEASLQGLERIFPTVS

Sequences:

>Translated_457_residues
MTTRLTRWLTTLDNFEAKMAQLPAVRRYGRLTRATGLVLEATGLQLPLGATCVIERQNGSETHEVESEVVGFNGQRLFLM
PLEEVEGVLPGARVYAKNISAEGLQSGKQLPLGPALLGRVLDGSGKPLDGLPFPDTTETGALITPPFNPLQRTPIEHVLD
TGVRPINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKDFIENILGAEGRARSVVIAAPAD
VSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMALREIALAIGEPPATKGYPPSVFAKLPALVERAGNGISGGG
SITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALISEQHYARVRTFKQLLSSFQR
NRDLVSVGAYAKGSDPMLDKAIALWPQLESYLQQGIFERADWEASLQGLERIFPTVS
>Mature_456_residues
TTRLTRWLTTLDNFEAKMAQLPAVRRYGRLTRATGLVLEATGLQLPLGATCVIERQNGSETHEVESEVVGFNGQRLFLMP
LEEVEGVLPGARVYAKNISAEGLQSGKQLPLGPALLGRVLDGSGKPLDGLPFPDTTETGALITPPFNPLQRTPIEHVLDT
GVRPINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKDFIENILGAEGRARSVVIAAPADV
SPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMALREIALAIGEPPATKGYPPSVFAKLPALVERAGNGISGGGS
ITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALISEQHYARVRTFKQLLSSFQRN
RDLVSVGAYAKGSDPMLDKAIALWPQLESYLQQGIFERADWEASLQGLERIFPTVS

Specific function: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum. May be involved in a specialized protein export pathway that proceeds without signal peptide cleavage [

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=347, Percent_Identity=28.8184438040346, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI50345984, Length=347, Percent_Identity=27.9538904899135, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI4757810, Length=347, Percent_Identity=27.9538904899135, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI19913426, Length=380, Percent_Identity=28.1578947368421, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI19913428, Length=402, Percent_Identity=27.8606965174129, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI19913424, Length=251, Percent_Identity=31.0756972111554, Blast_Score=117, Evalue=3e-26,
Organism=Escherichia coli, GI1788251, Length=457, Percent_Identity=99.3435448577681, Blast_Score=910, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=348, Percent_Identity=29.0229885057471, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1790172, Length=345, Percent_Identity=25.2173913043478, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1790217, Length=241, Percent_Identity=26.1410788381743, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI25144756, Length=313, Percent_Identity=29.3929712460064, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71988063, Length=428, Percent_Identity=28.0373831775701, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI71988080, Length=426, Percent_Identity=27.2300469483568, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=414, Percent_Identity=28.5024154589372, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17510931, Length=370, Percent_Identity=27.027027027027, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17565854, Length=301, Percent_Identity=29.9003322259136, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI71988074, Length=372, Percent_Identity=27.4193548387097, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319370, Length=345, Percent_Identity=28.695652173913, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6322581, Length=310, Percent_Identity=30.6451612903226, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6319603, Length=423, Percent_Identity=27.6595744680851, Blast_Score=121, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6320016, Length=264, Percent_Identity=29.1666666666667, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24638766, Length=310, Percent_Identity=29.6774193548387, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28574560, Length=331, Percent_Identity=30.2114803625378, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24658560, Length=346, Percent_Identity=27.4566473988439, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281361666, Length=399, Percent_Identity=28.0701754385965, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24646341, Length=399, Percent_Identity=28.0701754385965, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI17136796, Length=399, Percent_Identity=28.0701754385965, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24583992, Length=251, Percent_Identity=30.6772908366534, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24583988, Length=243, Percent_Identity=31.2757201646091, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583986, Length=243, Percent_Identity=31.2757201646091, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24583984, Length=243, Percent_Identity=31.2757201646091, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI20129479, Length=242, Percent_Identity=30.1652892561983, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005714
- InterPro:   IPR020005 [H]

Pfam domain/function: PF00006 ATP-synt_ab [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 49391; Mature: 49260

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRLTRWLTTLDNFEAKMAQLPAVRRYGRLTRATGLVLEATGLQLPLGATCVIERQNGS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEECCCCC
ETHEVESEVVGFNGQRLFLMPLEEVEGVLPGARVYAKNISAEGLQSGKQLPLGPALLGRV
CHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCHHHHHHCCCHHHHHCCCCCCCCHHHHHHH
LDGSGKPLDGLPFPDTTETGALITPPFNPLQRTPIEHVLDTGVRPINALLTVGRGQRMGL
HCCCCCCCCCCCCCCCCCCCEEECCCCCCHHCCCHHHHHHCCCHHHHHHHCCCCCCEEEE
FAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKDFIENILGAEGRARSVVIAAPAD
EECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCC
VSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMALREIALAIGEPPATKGYPPS
CHHHHHHCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
VFAKLPALVERAGNGISGGGSITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRRLAEA
HHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GHYPAIDIEASISRAMTALISEQHYARVRTFKQLLSSFQRNRDLVSVGAYAKGSDPMLDK
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHH
AIALWPQLESYLQQGIFERADWEASLQGLERIFPTVS
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTRLTRWLTTLDNFEAKMAQLPAVRRYGRLTRATGLVLEATGLQLPLGATCVIERQNGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCEEEEECCCCC
ETHEVESEVVGFNGQRLFLMPLEEVEGVLPGARVYAKNISAEGLQSGKQLPLGPALLGRV
CHHHHHHHHHCCCCCEEEEEEHHHHCCCCCCHHHHHHCCCHHHHHCCCCCCCCHHHHHHH
LDGSGKPLDGLPFPDTTETGALITPPFNPLQRTPIEHVLDTGVRPINALLTVGRGQRMGL
HCCCCCCCCCCCCCCCCCCCEEECCCCCCHHCCCHHHHHHCCCHHHHHHHCCCCCCEEEE
FAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKDFIENILGAEGRARSVVIAAPAD
EECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCEEEEECCCC
VSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMALREIALAIGEPPATKGYPPS
CHHHHHHCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
VFAKLPALVERAGNGISGGGSITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRRLAEA
HHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
GHYPAIDIEASISRAMTALISEQHYARVRTFKQLLSSFQRNRDLVSVGAYAKGSDPMLDK
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHH
AIALWPQLESYLQQGIFERADWEASLQGLERIFPTVS
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]