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The map label for this gene is cobT

Identifier: 218699443

GI number: 218699443

Start: 1116762

End: 1117841

Strand: Direct

Name: cobT

Synonym: ECIAI39_1056

Alternate gene names: 218699443

Gene position: 1116762-1117841 (Clockwise)

Preceding gene: 218699442

Following gene: 218699444

Centisome position: 21.76

GC content: 51.2

Gene sequence:

>1080_bases
ATGCAAATACTTGCCGATTTACTGAATACGATCCCAGCCATCAATTCTGCCGCTATGTCGCGTGCACAACGGCATGTTGA
CGGGTTACTCAAACCTGTTGGTAGCCTGGGAAAGCTGGAGGCGCTTGCCATACAACTGGCAGGAATGCCGGGGTTGAATG
GCATACCGCATGTGGGCAAAAAAGCAGTACTGGTTATGTGTGCCGATCACGGCGTCTGGGAGGAAGGGGTCGCTATTTCT
CCAAAAGAAGTGACAGCCATACAGGCTGAAAATATGACCCGTGGAACAACCGGCGTGTGTGTGCTGGCAGCACAAGCGGG
CGCTAACGTCCACGTAATTGATGTTGGTATTGATACTGCTGAGCCTATCCCCGGGCTTATCAACATGCGTGTCGCACGAG
GTAGCGGCAATATTGCTTCAGCTCCGGCAATGAGTCGCCGTCAGGCTGAAAAGTTGCTTTTGGACGTCATATGTTATACG
CGGGAGCTGGCAAAAAACGGTGTCACGCTGTTTGGTGTAGGTGAACTGGGGATGGCAAACACGACACCGGCAGCGGCAAT
AGTCAGCACAATCACTGGCCGGGATCCTGAAGAAGTGGTTGGGATTGGCGCAAACCTGCCGACAGATAAACTGGCTAATA
AAATTGATGTTGTGCGTCGGGCGATTACGTTGAATCAACCAAATCCTCAGGATGGTGTTGATGTCCTGGCAAAAGTGGGT
GGATTTGATTTGGTCGGAATAGCTGGAGTGATGTTAGGTGCTGCTTCCTGCGGTTTACCCGTGTTGCTGGATGGATTTCT
TTCTTATGCTGCTGCGCTCGCAGCCTGCCAGATGTCTCCTGCAATCAAACCGTATCTCATTCCTTCTCACTTGTCGGCAG
AAAAAGGCGCGCGTATAGCGCTCTCGCATTTGGGGCTGGAGCCTTATCTCAATATGGATATGCGTTTAGGTGAGGGGAGT
GGTGCAGCTCTGGCGATGTCCATCATCGAAGCTGCTTGTGCGATATACAACAACATGGGCGAACTTGCTGCCAGTAATAT
TGTTCTACCGGGGAATACGACTTCTGATTTGAACAGCTAA

Upstream 100 bases:

>100_bases
TCAAACGTACGCTGGGCGGGCAAACGGGCGATACGCTGGGAGCAGCCATAGAGTTTGGTGAACTGGTTTTCCTGCTGGCA
CTGCTATAAAGAGACGTGAC

Downstream 100 bases:

>100_bases
AAACGAAAAGTCTGATAAAAGCTATACTTATCGGATAGTATTCGCGACTTAGGAAAGGGACATGATGCGTCGTGTAAATA
TTCTTTGCTCATTTGCTCTG

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MQILADLLNTIPAINSAAMSRAQRHVDGLLKPVGSLGKLEALAIQLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAIS
PKEVTAIQAENMTRGTTGVCVLAAQAGANVHVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYT
RELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVG
GFDLVGIAGVMLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMDMRLGEGS
GAALAMSIIEAACAIYNNMGELAASNIVLPGNTTSDLNS

Sequences:

>Translated_359_residues
MQILADLLNTIPAINSAAMSRAQRHVDGLLKPVGSLGKLEALAIQLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAIS
PKEVTAIQAENMTRGTTGVCVLAAQAGANVHVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYT
RELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVG
GFDLVGIAGVMLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMDMRLGEGS
GAALAMSIIEAACAIYNNMGELAASNIVLPGNTTSDLNS
>Mature_359_residues
MQILADLLNTIPAINSAAMSRAQRHVDGLLKPVGSLGKLEALAIQLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAIS
PKEVTAIQAENMTRGTTGVCVLAAQAGANVHVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYT
RELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVG
GFDLVGIAGVMLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMDMRLGEGS
GAALAMSIIEAACAIYNNMGELAASNIVLPGNTTSDLNS

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=359, Percent_Identity=97.7715877437326, Blast_Score=703, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 36860; Mature: 36860

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQILADLLNTIPAINSAAMSRAQRHVDGLLKPVGSLGKLEALAIQLAGMPGLNGIPHVGK
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEECCCCCCCCCCCCCC
KAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVLAAQAGANVHVIDVGIDTA
CEEEEEEECCCCCCCCCEECCHHEEEEECCCCCCCCCCEEEEEECCCCEEEEEEECCCCC
EPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYTRELAKNGVTLFGVGELGMAN
CCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
TTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVG
CCHHHHHHHHHCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHC
GFDLVGIAGVMLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIA
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCEEE
LSHLGLEPYLNMDMRLGEGSGAALAMSIIEAACAIYNNMGELAASNIVLPGNTTSDLNS
HHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCC
>Mature Secondary Structure
MQILADLLNTIPAINSAAMSRAQRHVDGLLKPVGSLGKLEALAIQLAGMPGLNGIPHVGK
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHEECCCCCCCCCCCCCC
KAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVLAAQAGANVHVIDVGIDTA
CEEEEEEECCCCCCCCCEECCHHEEEEECCCCCCCCCCEEEEEECCCCEEEEEEECCCCC
EPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYTRELAKNGVTLFGVGELGMAN
CCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
TTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVG
CCHHHHHHHHHCCCCHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHC
GFDLVGIAGVMLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIA
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCEEE
LSHLGLEPYLNMDMRLGEGSGAALAMSIIEAACAIYNNMGELAASNIVLPGNTTSDLNS
HHHCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA