Click here to switch to the map view.

The map label for this gene is ybhD

Identifier: 218699133

GI number: 218699133

Start: 778470

End: 779486

Strand: Reverse

Name: ybhD

Synonym: ECIAI39_0736

Alternate gene names: 218699133

Gene position: 779486-778470 (Counterclockwise)

Preceding gene: 218699137

Following gene: 218699131

Centisome position: 15.19

GC content: 44.94

Gene sequence:

>1017_bases
ATGCAGTTAAAATTTTTAACGGCCAGCCACCCAAAATCGACGCTTCCATTTTCCGGAGTAATAATGAAGCATGAATTATC
AAGTATGAAGGCATTTGTCATACTGGCAGAGTCCAGTTCATTTAACAATGCCGCTAAATTACTCAATATTACGCAACCTG
CATTAACGCGAAGAATAAAAAAGATGGAGGAAGATTTACATATCCAACTATTTGAGCGTACAACTCGCAAGGTTACGTTA
ACAAAAGCAGGAAAAAGATTGCTCCCGGAGGCGCGGGAATTAATAAAGAAATTCGATGAAACGCTTTTTAATATTCGTGA
TATGAATGCTTATCATCGTGGTATGGTGACATTAGCGTGTATTCCGACCGCAGTATTTTATTTTTTACCGCTGGCAATCG
GTAAATTTAATGAGCTGTATCCCAATATTAAAGTGCGGATTCTGGAACAAGGCACGAATAATTGCATGGAATCGGTGCTG
TGTAACGAATCAGACTTTGGCATAAACATGAACAACGTCACAAATTCATCCATCGATTTTACCCCACTGGTCAACGAGCC
GTTCGTGCTGGCCTGTCGGCGTGACCATCCATTGGCCAAAAAGCAGCTTGTAGAATGGCAGGAGTTAGTGGGTTACAAAA
TGATTGGCGTACGCTCCTCCAGCGGCAACCGACTGTTGATAGAACAACAGCTAGCCGACAAGCCCTGGAAGCTGGACTGG
TTTTACGAAGTGCGTCATCTTTCGACGTCATTAGGGCTGGTGGAGGCGGGACTGGGGATTTCGGCGCTTCCTGGTCTGGC
AATGCCCCATGCGCCCTATTCTTCGATTATTGGTATCCCACTGGTGGAACCCGTTATACGTCGGACATTGGGGATTATTC
GCCGCAAAGATGCCGTGCTTTCTCCGGCAGCTGAACGCTTTTTTGCCTTGCTGATTAATTTGTGGACTGACGATAAAGAC
AATTTGTGGACCAATATCGTCGAACGCCAGAGACATGCGTTACAGGAGATAGGTTAA

Upstream 100 bases:

>100_bases
CCATCATACACTAAATCAGTAAGTTGGCAGCATTACCAGCATCTCTAATGACTTTAGCTCAACGATTAATAACTTTTTTT
CATTAATTTAAGTTGGCTAA

Downstream 100 bases:

>100_bases
TACACCGGCGCAGGAGAGACTGCGCCGGTTAAATCAGCGGTTAGTGCGCGTTGACCACTACCCACATTGGCCCCTGCCCA
ACCGCATAGCGGCCTTTTTC

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MQLKFLTASHPKSTLPFSGVIMKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHIQLFERTTRKVTL
TKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVL
CNESDFGINMNNVTNSSIDFTPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDW
FYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVLSPAAERFFALLINLWTDDKD
NLWTNIVERQRHALQEIG

Sequences:

>Translated_338_residues
MQLKFLTASHPKSTLPFSGVIMKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHIQLFERTTRKVTL
TKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVL
CNESDFGINMNNVTNSSIDFTPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDW
FYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVLSPAAERFFALLINLWTDDKD
NLWTNIVERQRHALQEIG
>Mature_338_residues
MQLKFLTASHPKSTLPFSGVIMKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHIQLFERTTRKVTL
TKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVL
CNESDFGINMNNVTNSSIDFTPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDW
FYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVLSPAAERFFALLINLWTDDKD
NLWTNIVERQRHALQEIG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=317, Percent_Identity=99.6845425867508, Blast_Score=655, Evalue=0.0,
Organism=Escherichia coli, GI1788748, Length=287, Percent_Identity=32.7526132404181, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1790399, Length=283, Percent_Identity=27.208480565371, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI157672245, Length=284, Percent_Identity=27.8169014084507, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787879, Length=295, Percent_Identity=27.1186440677966, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787601, Length=188, Percent_Identity=28.7234042553192, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1788887, Length=243, Percent_Identity=25.5144032921811, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789204, Length=268, Percent_Identity=24.2537313432836, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790208, Length=294, Percent_Identity=24.8299319727891, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788481, Length=290, Percent_Identity=24.8275862068966, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788706, Length=168, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788297, Length=238, Percent_Identity=23.109243697479, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI2367136, Length=246, Percent_Identity=27.6422764227642, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787589, Length=195, Percent_Identity=25.6410256410256, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786401, Length=165, Percent_Identity=27.8787878787879, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786713, Length=249, Percent_Identity=29.718875502008, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787530, Length=180, Percent_Identity=25.5555555555556, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87081904, Length=298, Percent_Identity=22.4832214765101, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789173, Length=143, Percent_Identity=29.3706293706294, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787806, Length=288, Percent_Identity=20.8333333333333, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787128, Length=160, Percent_Identity=28.75, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788296, Length=232, Percent_Identity=25.4310344827586, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082132, Length=283, Percent_Identity=22.6148409893993, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786508, Length=176, Percent_Identity=25, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 38357; Mature: 38357

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLKFLTASHPKSTLPFSGVIMKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIK
CEEEEEECCCCCCCCCCCCCHHHHHHHCCEEEEEEECCCCCCCHHHHHCCCHHHHHHHHH
KMEEDLHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLAC
HHHHHHHHHHHHHHHHEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHH
IPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDF
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCCCCEEECCCCCCCCCE
TPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDW
EECCCCCEEEEECCCCCHHHHHHHHHHHHHCEEEEEEECCCCCEEEEEHHHCCCCCCCHH
FYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVL
HHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHC
SPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLKFLTASHPKSTLPFSGVIMKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIK
CEEEEEECCCCCCCCCCCCCHHHHHHHCCEEEEEEECCCCCCCHHHHHCCCHHHHHHHHH
KMEEDLHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLAC
HHHHHHHHHHHHHHHHEEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHCCHHHHCHHHHHH
IPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDF
HHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHCCCCCCCEEECCCCCCCCCE
TPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDW
EECCCCCEEEEECCCCCHHHHHHHHHHHHHCEEEEEEECCCCCEEEEEHHHCCCCCCCHH
FYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVL
HHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHC
SPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]