Click here to switch to the map view.

The map label for this gene is entD

Identifier: 218698954

GI number: 218698954

Start: 587796

End: 588425

Strand: Reverse

Name: entD

Synonym: ECIAI39_0557

Alternate gene names: 218698954

Gene position: 588425-587796 (Counterclockwise)

Preceding gene: 218698957

Following gene: 218698953

Centisome position: 11.47

GC content: 48.41

Gene sequence:

>630_bases
ATGGTCGACATGAAAACTACGCATACCGCCCTCCCCTTTACCGGACATACGCTGCATTTTGTTGAGTTCGATCCTGCGAG
TTTTCGCGAGCAGGATTTACTCTGGCTGCCGCACTACGCGCAACTGCAACACGCTGGACGTAAACGTAAAACAGAGCATT
TAGCCGGACGGATCGCTGCAGTTTATGCGCTGCGGGAATATGGCTATAAATGTGTGCCCGCAATCGGCGAGCTACGCCAA
CCTGTGTGGCCTGCGGGGGTATACGGCAGCATTAGTCACTGTGGGACTACGGCATTAGCCGTGGTATCTCGTCAACCGAT
TGGCATTGATATCGAAGAGATTTTCTCTGTACAAACCGCAAGAGAATTGACAGACAACATTATTACACCAGCAGAACACG
AGCGACTCGCAGAATGCGGTTTAACCTTTTCTCTGGCGCTGACACTGGCATTTTCCGCCAAAGAAAGCGCATTTAAGGCA
AGCAAGATACAGGCCGCTCAAGGTTTTCTGGATTATCAGATAATTAGCTGGAATAAACAGCGGATCATCATTCATCGTGA
GAATGAGATGTTTGCTGTGCACTGGCAGATAAAAGAAAAAATAGTCATAACGCTGTGCCAACACGATTAA

Upstream 100 bases:

>100_bases
CGGCCTACAAAAATCTTGCCAATTCAATATATTGCAGGATAGTGTAGGCCTGATAAGCGTAGCGCATCAGGCAGTTTTGC
GTTTGTCATCAGTCTCTAAT

Downstream 100 bases:

>100_bases
TTGACAACATCTGGTACGATTCGCCCGCAGCCATTACTGACCGCGGGCGAAAGTGTAAAGCAGGTGCCTTACCATCCTGA
CCTGACAACCGGATATGCGG

Product: phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex

Products: NA

Alternate protein names: Enterobactin synthase component D; Enterochelin synthase D [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MVDMKTTHTALPFTGHTLHFVEFDPASFREQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYALREYGYKCVPAIGELRQ
PVWPAGVYGSISHCGTTALAVVSRQPIGIDIEEIFSVQTARELTDNIITPAEHERLAECGLTFSLALTLAFSAKESAFKA
SKIQAAQGFLDYQIISWNKQRIIIHRENEMFAVHWQIKEKIVITLCQHD

Sequences:

>Translated_209_residues
MVDMKTTHTALPFTGHTLHFVEFDPASFREQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYALREYGYKCVPAIGELRQ
PVWPAGVYGSISHCGTTALAVVSRQPIGIDIEEIFSVQTARELTDNIITPAEHERLAECGLTFSLALTLAFSAKESAFKA
SKIQAAQGFLDYQIISWNKQRIIIHRENEMFAVHWQIKEKIVITLCQHD
>Mature_209_residues
MVDMKTTHTALPFTGHTLHFVEFDPASFREQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYALREYGYKCVPAIGELRQ
PVWPAGVYGSISHCGTTALAVVSRQPIGIDIEEIFSVQTARELTDNIITPAEHERLAECGLTFSLALTLAFSAKESAFKA
SKIQAAQGFLDYQIISWNKQRIIIHRENEMFAVHWQIKEKIVITLCQHD

Specific function: Catalyzes the transfer of the 4'-phosphopantetheine moiety from coenzyme A to apo-domains of both entB (an ArCP domain) and entF (a PCP domain). Plays an essential role in the assembly of the enterobactin [H]

COG id: COG2977

COG function: function code Q; Phosphopantetheinyl transferase component of siderophore synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. EntD family [H]

Homologues:

Organism=Escherichia coli, GI1786797, Length=209, Percent_Identity=93.7799043062201, Blast_Score=412, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008278
- InterPro:   IPR003542 [H]

Pfam domain/function: PF01648 ACPS [H]

EC number: 2.7.8.-

Molecular weight: Translated: 23640; Mature: 23640

Theoretical pI: Translated: 7.36; Mature: 7.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDMKTTHTALPFTGHTLHFVEFDPASFREQDLLWLPHYAQLQHAGRKRKTEHLAGRIAA
CCCCCCCCEECCCCCCEEEEEEECCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHH
VYALREYGYKCVPAIGELRQPVWPAGVYGSISHCGTTALAVVSRQPIGIDIEEIFSVQTA
HHHHHHCCCEECCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
RELTDNIITPAEHERLAECGLTFSLALTLAFSAKESAFKASKIQAAQGFLDYQIISWNKQ
HHHHHHCCCCCHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHHCCEEEEEEEECCE
RIIIHRENEMFAVHWQIKEKIVITLCQHD
EEEEEECCCEEEEEEEECCEEEEEEECCC
>Mature Secondary Structure
MVDMKTTHTALPFTGHTLHFVEFDPASFREQDLLWLPHYAQLQHAGRKRKTEHLAGRIAA
CCCCCCCCEECCCCCCEEEEEEECCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHH
VYALREYGYKCVPAIGELRQPVWPAGVYGSISHCGTTALAVVSRQPIGIDIEEIFSVQTA
HHHHHHCCCEECCCHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
RELTDNIITPAEHERLAECGLTFSLALTLAFSAKESAFKASKIQAAQGFLDYQIISWNKQ
HHHHHHCCCCCHHHHHHHHCCCEEEEEEEEECCCHHHHHHHHHHHHHCCEEEEEEEECCE
RIIIHRENEMFAVHWQIKEKIVITLCQHD
EEEEEECCCEEEEEEEECCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]