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The map label for this gene is rbsC [H]

Identifier: 218698767

GI number: 218698767

Start: 390093

End: 391079

Strand: Reverse

Name: rbsC [H]

Synonym: ECIAI39_0357

Alternate gene names: 218698767

Gene position: 391079-390093 (Counterclockwise)

Preceding gene: 218698768

Following gene: 218698766

Centisome position: 7.62

GC content: 51.98

Gene sequence:

>987_bases
GTGGAGTCAGCATCAGAACCGGAGTCTGCTATGAAAAAATCGTGGCGTAATAACGTTGAGTTTTACTTGATCGGCCTGCT
GGTGCTAACTGTTGCCGCGTTCAGCATTACTATGCCGGAGATTTTCTGGTCGATAAGTAATTTCCAGTCCGTCGCTTCGC
AAATGCCCGTGCTGGGCATTCTGGCGTTGGCTATGGCGGTGACCATGCTTTGCGGTGGCATTAACTTGTCAATTATAGCC
ACTGCTAACGCCTGTTCACTGGTGATGGCGTGGGTGGCGACTCAGTATCCACCGGGTATTGCTACGGTTGTCGCTACGTT
ACTGGCGGGCGCTGGCGCGGCGGTGATAATCGGTTTATGTAACGGCGTATTGATTGCTGGTATTCGAGTGTCGCCAATTC
TTGCAACGCTTGGGATGATGACGTTGCTCAAAGGGGTAAATATTCTGGTGACAGGCGGTAGCGCCATTGCCAATTATCCC
TCATGGGTGCTGTGGTTGAATCATGCACAGTGGTTCGGTATTCCGCTACCGATGTGGTTGTTTACCGCAGTGGCGCTGGG
GCTGTGGATATTGCTGGAGAAAACGCCGCTCGGTAAAGCCATTTACCTGATTGGGTCTAACGAACGAGCAACACTTTACT
CCGGCATTAACACTCGTCGGGTGCTGATTTGGGTTTATGTCATTTCCGCCTTGCTTTGTGCGGTAGCGGCATTTTTGATG
ATGTCGAAACTCAACTCGGCTAAGGCCTCTTATGGCGAATCGTACTTGCTGGTGTCAATCCTCGCGGCAGTACTCGGCGG
GGTTAATCCGGACGGCGGCAGCGGGCGGATAATTGGTATGGTGCTGGCGCTGTTTCTTCTGCAAATTATTGAAAGCGGCT
TCAATATTCTCGGTATAAGCCCCTACCTGACGATGGCCTTATGGGGAACGTTGCTGCTCTGTTTCATTCAGGCTCGCGGC
ATGTTGGGGCTGGATCGGGTGGTTTAA

Upstream 100 bases:

>100_bases
TGGCAGTGATGCAAAACGGGCTAAATTTATTGGGAGTCTCGTCTTACTGGCAAACATTGATCACCGGCATCATCATCGTT
GCCAGCATTAGCGCCACGGC

Downstream 100 bases:

>100_bases
ATATTGGCTATATTCAATGGACGCGTTTTGCCGCGATGACATATCAGGCATCGCCAAATACACATAGCTAATCAGGAGTA
AACACAATGAAGATCAGAGC

Product: sugar ABC transporter permease

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MESASEPESAMKKSWRNNVEFYLIGLLVLTVAAFSITMPEIFWSISNFQSVASQMPVLGILALAMAVTMLCGGINLSIIA
TANACSLVMAWVATQYPPGIATVVATLLAGAGAAVIIGLCNGVLIAGIRVSPILATLGMMTLLKGVNILVTGGSAIANYP
SWVLWLNHAQWFGIPLPMWLFTAVALGLWILLEKTPLGKAIYLIGSNERATLYSGINTRRVLIWVYVISALLCAVAAFLM
MSKLNSAKASYGESYLLVSILAAVLGGVNPDGGSGRIIGMVLALFLLQIIESGFNILGISPYLTMALWGTLLLCFIQARG
MLGLDRVV

Sequences:

>Translated_328_residues
MESASEPESAMKKSWRNNVEFYLIGLLVLTVAAFSITMPEIFWSISNFQSVASQMPVLGILALAMAVTMLCGGINLSIIA
TANACSLVMAWVATQYPPGIATVVATLLAGAGAAVIIGLCNGVLIAGIRVSPILATLGMMTLLKGVNILVTGGSAIANYP
SWVLWLNHAQWFGIPLPMWLFTAVALGLWILLEKTPLGKAIYLIGSNERATLYSGINTRRVLIWVYVISALLCAVAAFLM
MSKLNSAKASYGESYLLVSILAAVLGGVNPDGGSGRIIGMVLALFLLQIIESGFNILGISPYLTMALWGTLLLCFIQARG
MLGLDRVV
>Mature_328_residues
MESASEPESAMKKSWRNNVEFYLIGLLVLTVAAFSITMPEIFWSISNFQSVASQMPVLGILALAMAVTMLCGGINLSIIA
TANACSLVMAWVATQYPPGIATVVATLLAGAGAAVIIGLCNGVLIAGIRVSPILATLGMMTLLKGVNILVTGGSAIANYP
SWVLWLNHAQWFGIPLPMWLFTAVALGLWILLEKTPLGKAIYLIGSNERATLYSGINTRRVLIWVYVISALLCAVAAFLM
MSKLNSAKASYGESYLLVSILAAVLGGVNPDGGSGRIIGMVLALFLLQIIESGFNILGISPYLTMALWGTLLLCFIQARG
MLGLDRVV

Specific function: Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790191, Length=309, Percent_Identity=33.6569579288026, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1787794, Length=312, Percent_Identity=31.0897435897436, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI145693152, Length=250, Percent_Identity=30, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1790524, Length=329, Percent_Identity=25.531914893617, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788896, Length=326, Percent_Identity=28.5276073619632, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI145693214, Length=249, Percent_Identity=29.3172690763052, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789992, Length=120, Percent_Identity=31.6666666666667, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI87082395, Length=276, Percent_Identity=27.8985507246377, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788471, Length=320, Percent_Identity=29.375, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787793, Length=286, Percent_Identity=29.3706293706294, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 34803; Mature: 34803

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESASEPESAMKKSWRNNVEFYLIGLLVLTVAAFSITMPEIFWSISNFQSVASQMPVLGI
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LALAMAVTMLCGGINLSIIATANACSLVMAWVATQYPPGIATVVATLLAGAGAAVIIGLC
HHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHH
NGVLIAGIRVSPILATLGMMTLLKGVNILVTGGSAIANYPSWVLWLNHAQWFGIPLPMWL
HHHHEECCHHHHHHHHHHHHHHHCCCEEEEECCHHHHCCCCEEEEECCCCCCCCCHHHHH
FTAVALGLWILLEKTPLGKAIYLIGSNERATLYSGINTRRVLIWVYVISALLCAVAAFLM
HHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
MSKLNSAKASYGESYLLVSILAAVLGGVNPDGGSGRIIGMVLALFLLQIIESGFNILGIS
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECH
PYLTMALWGTLLLCFIQARGMLGLDRVV
HHHHHHHHHHHHHHHHHHCCCCCHHHCC
>Mature Secondary Structure
MESASEPESAMKKSWRNNVEFYLIGLLVLTVAAFSITMPEIFWSISNFQSVASQMPVLGI
CCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LALAMAVTMLCGGINLSIIATANACSLVMAWVATQYPPGIATVVATLLAGAGAAVIIGLC
HHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHH
NGVLIAGIRVSPILATLGMMTLLKGVNILVTGGSAIANYPSWVLWLNHAQWFGIPLPMWL
HHHHEECCHHHHHHHHHHHHHHHCCCEEEEECCHHHHCCCCEEEEECCCCCCCCCHHHHH
FTAVALGLWILLEKTPLGKAIYLIGSNERATLYSGINTRRVLIWVYVISALLCAVAAFLM
HHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
MSKLNSAKASYGESYLLVSILAAVLGGVNPDGGSGRIIGMVLALFLLQIIESGFNILGIS
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECH
PYLTMALWGTLLLCFIQARGMLGLDRVV
HHHHHHHHHHHHHHHHHHCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]