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The map label for this gene is malZ

Identifier: 218698693

GI number: 218698693

Start: 309775

End: 311592

Strand: Reverse

Name: malZ

Synonym: ECIAI39_0279

Alternate gene names: 218698693

Gene position: 311592-309775 (Counterclockwise)

Preceding gene: 218698694

Following gene: 218698692

Centisome position: 6.07

GC content: 55.06

Gene sequence:

>1818_bases
ATGATGTTAAATGCATGGCATCTGCCGGTGCCCCCATTTGTTAAACAAAGCAAAGATCAACTGCTCATTACGCTGTGGCT
GACGGGTGAAGACCCACCGCAGCGCATTATGCTGCGTACAGAACACGACAACGAAGAAACGTCAGTAGCGATGCATAAGC
AGCGCAGTCAGCCGCAGCCTGGCGTTACCGCATGGCGGGCGGCGATCGATCTCTCCAGCGGGCAACCTCGGCGGCGTTAT
AGTTTCAAATTACTGTGGCACGATCGCCAGCGTTGGTTTACACCGCAGGGCTTCAGCCGAATGCCGCCAGCACGACTGGA
GCAGTTTGCTGTCGATGTCCCGGATATCGGCCCACAATGGGCTGCGGATCAGATTTTTTATCAGATCTTCCCTGATCGTT
TCGCCCGTAGTCTTCCTCGTGAAGCTGAACAGGATCATGTTTATTACCATCACGCAGCCGGACAAGAGATCATATTGCGT
GACTGGGATGAACCGGTCACGGCGCAGGCGGGCGGATCAACGTTCTATGGCGGCGATCTGGACGGTATCAGCGAAAAACT
GCCGTATCTGAAAAAGCTCGGCGTGACGGCGCTGTATCTTAACCCGGTGTTTAAAGCCCCCAGCGTACATAAATACGATA
CAGAGGATTATCGCCACGTCGATCCGCAGTTTGGCGGCGACGGAGCGTTACTGCGTTTACGACACCATACGCAGCAGCTG
GGAATGCGGCTGGTGCTGGACGGCGTGTTTAACCACAGTGGCGATTCCCATGCCTGGTTTGACAGACACAATCGCGGGAC
GGGTGGTGCTTGTCACAACCCCGAATCGCCCTGGCGCGACTGGTACTCGTTTAGTGACGATGGCACGGCGCTCGACTGGC
TGGGCTATGCCAGCTTGCCGAAGCTGGATTATCAGTCGGAAAGTCTGGTGAATGAAATTTATCGCGGGGAAGACAGTATT
GTCCGCCACTGGCTGAAAGCGCCGTGGAATATGGACGGCTGGCGGCTGGATGTGGTGCATATGCTGGGGGAAGCGGGTGG
GGCGCGCAATAATTTGCAGCACGTTGCCGGGATCACCGAAGCGGCGAAAGAAACCCAGCCGGAAGCGTATATCGTTGGAG
AGCATTTTGGCGATGCACGGCAATGGTTACAGGCCGATGTGGAAGATGCCGCCATGAACTATCGTGGCTTCACATTCCCG
TTGTGGGGATTTCTTGCCAATACCGACATCTCTTATGATCCGCAGCAAATTGACGCCCAAACCTGTATGGCCTGGATGGA
TAATTACCGCGCCGGACTTTCTCATCAACAGCAACTGCGTATGTTTAATCAGCTCGATAGCCACGATACTGCGCGATTTA
AAACGCTGCTCGGTCGGGATATTGCGCGCCTGCCGCTGGCGGTGGTCTGGTTGTTCACCTGGCCTGGTGTACCGTGCATT
TATTACGGTGATGAAGTGGGACTGGATGGTAAAAACGATCCGTTTTGCCGTAAGCCGTTCCCCTGGCAGGTGGAAAAGCA
GGATACGGCGTTATTCGCGTTGTACCAGCGAATGATTGCGCTGCGTAAGAAAAGTCAGGCGCTGCGTCGTGGCGGCTGTC
AGGTGCTGTATGCGGAAGATAACGTGGTGGTATTTGTCCGCGTGCTGAATCAGCAGCGTGTACTGGTGGCAATCAACCGT
GGCGAGGCCTGTGAAGTGGTGCTACCCGCGTCACCGTTGCTTAATGTTGCGCAATGGCAACGCAAAGAAGGCCATGGGCA
ACTGACAGACGGGATTCTGGCTTTGCCTGCCATTTCGGCTACGGTGTGGATCAACTAA

Upstream 100 bases:

>100_bases
GTTATCCGCCCCCGTCCTCCTCCCCCAAATATCCTTCAGATGATGAGTGATCCTGCATTAGGCTATGGCAAGGTGATCAG
ATTTTCATCACAGGGGAATT

Downstream 100 bases:

>100_bases
AGCATCTGTTTTATTTGTTACGTCGTTAGTCACCAGCCCTGACACTACGCAGCGAAAAAGCTGCTCAATGTCAGGGCTGA
ATTTGTTAAATATTTGTCCC

Product: maltodextrin glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase [H]

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDNEETSVAMHKQRSQPQPGVTAWRAAIDLSSGQPRRRY
SFKLLWHDRQRWFTPQGFSRMPPARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILR
DWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYRHVDPQFGGDGALLRLRHHTQQL
GMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPESPWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSI
VRHWLKAPWNMDGWRLDVVHMLGEAGGARNNLQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAMNYRGFTFP
LWGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGRDIARLPLAVVWLFTWPGVPCI
YYGDEVGLDGKNDPFCRKPFPWQVEKQDTALFALYQRMIALRKKSQALRRGGCQVLYAEDNVVVFVRVLNQQRVLVAINR
GEACEVVLPASPLLNVAQWQRKEGHGQLTDGILALPAISATVWIN

Sequences:

>Translated_605_residues
MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDNEETSVAMHKQRSQPQPGVTAWRAAIDLSSGQPRRRY
SFKLLWHDRQRWFTPQGFSRMPPARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILR
DWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYRHVDPQFGGDGALLRLRHHTQQL
GMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPESPWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSI
VRHWLKAPWNMDGWRLDVVHMLGEAGGARNNLQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAMNYRGFTFP
LWGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGRDIARLPLAVVWLFTWPGVPCI
YYGDEVGLDGKNDPFCRKPFPWQVEKQDTALFALYQRMIALRKKSQALRRGGCQVLYAEDNVVVFVRVLNQQRVLVAINR
GEACEVVLPASPLLNVAQWQRKEGHGQLTDGILALPAISATVWIN
>Mature_605_residues
MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDNEETSVAMHKQRSQPQPGVTAWRAAIDLSSGQPRRRY
SFKLLWHDRQRWFTPQGFSRMPPARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILR
DWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYRHVDPQFGGDGALLRLRHHTQQL
GMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPESPWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSI
VRHWLKAPWNMDGWRLDVVHMLGEAGGARNNLQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAMNYRGFTFP
LWGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGRDIARLPLAVVWLFTWPGVPCI
YYGDEVGLDGKNDPFCRKPFPWQVEKQDTALFALYQRMIALRKKSQALRRGGCQVLYAEDNVVVFVRVLNQQRVLVAINR
GEACEVVLPASPLLNVAQWQRKEGHGQLTDGILALPAISATVWIN

Specific function: May play a role in regulating the intracellular level of maltotriose. Cleaves glucose from the reducing end of maltotriose and longer maltodextrins with a chain length of up to 7 glucose units [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Escherichia coli, GI1786604, Length=605, Percent_Identity=98.3471074380165, Blast_Score=1236, Evalue=0.0,
Organism=Escherichia coli, GI1790687, Length=188, Percent_Identity=31.3829787234043, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1789995, Length=143, Percent_Identity=30.0699300699301, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322245, Length=194, Percent_Identity=27.8350515463918, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321726, Length=262, Percent_Identity=24.4274809160305, Blast_Score=77, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6322241, Length=198, Percent_Identity=26.7676767676768, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6322021, Length=198, Percent_Identity=26.7676767676768, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6324416, Length=198, Percent_Identity=26.7676767676768, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321731, Length=172, Percent_Identity=28.4883720930233, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6319776, Length=172, Percent_Identity=28.4883720930233, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24586599, Length=505, Percent_Identity=24.7524752475248, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24586593, Length=508, Percent_Identity=24.0157480314961, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24586589, Length=372, Percent_Identity=27.1505376344086, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24586591, Length=203, Percent_Identity=28.0788177339901, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24586597, Length=500, Percent_Identity=24, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45549022, Length=199, Percent_Identity=28.643216080402, Blast_Score=80, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24583747, Length=374, Percent_Identity=25.4010695187166, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24583749, Length=374, Percent_Identity=24.8663101604278, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24586587, Length=93, Percent_Identity=40.8602150537634, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221330053, Length=517, Percent_Identity=21.2765957446809, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24583745, Length=236, Percent_Identity=24.1525423728814, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR004185
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783
- InterPro:   IPR014756
- InterPro:   IPR017069 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF02903 Alpha-amylase_N [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 69142; Mature: 69142

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDNEETSVAMHKQRSQPQP
CCCCCCCCCCCHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCC
GVTAWRAAIDLSSGQPRRRYSFKLLWHDRQRWFTPQGFSRMPPARLEQFAVDVPDIGPQW
CHHHHHHEEECCCCCCCCEEEEEEEEECCHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCH
AADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILRDWDEPVTAQAGGSTFYGGDL
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCEECCCCC
DGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYRHVDPQFGGDGALLRLRHHTQQL
CCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHH
GMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPESPWRDWYSFSDDGTALDWLGYASLP
HHHHEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEECCCCCCC
KLDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGWRLDVVHMLGEAGGARNNLQHVAGITE
CCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEHHHHHHHCCCCCCCCHHHHHHHHH
AAKETQPEAYIVGEHFGDARQWLQADVEDAAMNYRGFTFPLWGFLANTDISYDPQQIDAQ
HHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCHHHHHHH
TCMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGRDIARLPLAVVWLFTWPGVPCI
HHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
YYGDEVGLDGKNDPFCRKPFPWQVEKQDTALFALYQRMIALRKKSQALRRGGCQVLYAED
EECCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
NVVVFVRVLNQQRVLVAINRGEACEVVLPASPLLNVAQWQRKEGHGQLTDGILALPAISA
CEEEEEEEECCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCEEECCCCEE
TVWIN
EEEEC
>Mature Secondary Structure
MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDNEETSVAMHKQRSQPQP
CCCCCCCCCCCHHHHCCCCCEEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCC
GVTAWRAAIDLSSGQPRRRYSFKLLWHDRQRWFTPQGFSRMPPARLEQFAVDVPDIGPQW
CHHHHHHEEECCCCCCCCEEEEEEEEECCHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCH
AADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILRDWDEPVTAQAGGSTFYGGDL
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCEECCCCC
DGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYRHVDPQFGGDGALLRLRHHTQQL
CCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHH
GMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPESPWRDWYSFSDDGTALDWLGYASLP
HHHHEEHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEECCCCCCC
KLDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGWRLDVVHMLGEAGGARNNLQHVAGITE
CCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEHHHHHHHCCCCCCCCHHHHHHHHH
AAKETQPEAYIVGEHFGDARQWLQADVEDAAMNYRGFTFPLWGFLANTDISYDPQQIDAQ
HHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCHHHHHHH
TCMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGRDIARLPLAVVWLFTWPGVPCI
HHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
YYGDEVGLDGKNDPFCRKPFPWQVEKQDTALFALYQRMIALRKKSQALRRGGCQVLYAED
EECCEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECC
NVVVFVRVLNQQRVLVAINRGEACEVVLPASPLLNVAQWQRKEGHGQLTDGILALPAISA
CEEEEEEEECCCEEEEEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCEEECCCCEE
TVWIN
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1918057; 9278503; 1706703 [H]