Click here to switch to the map view.

The map label for this gene is hofC

Identifier: 218698526

GI number: 218698526

Start: 124626

End: 125828

Strand: Reverse

Name: hofC

Synonym: ECIAI39_0106

Alternate gene names: 218698526

Gene position: 125828-124626 (Counterclockwise)

Preceding gene: 218698527

Following gene: 218698524

Centisome position: 2.45

GC content: 51.87

Gene sequence:

>1203_bases
ATGGCGAGTAAGCAACTCTGGCGCTGGCATGGCATAACCGGCGACGGCAATGCGCAAGATGGGATGCTATGGGCTGAGAG
CCGTGCTTTGCTGCTCATAGCACTACAGCAACAGATGGTTACCCCACTTAGCCTGAAGCGAATCGCCATCAATTCTGCGC
AGTGGCGAGGAGATAAAAGCGCGGAAGTCATTCATCAACTGGCGACGCTACTCAAAGCCGGGTTAACGCTTTCTGAAGGG
CTGGCACTGCTGGCGGAACAGCATTCCAGTAAGCAATGGCAAGCGTTGCTGCAATCGCTGGCGTACGATCTCGAACAGGG
CATTGCCTTTTCCAATGCCTTATTACCCTGGTCAGAGGTATTTCCGCCGCTCTATCAGGCAATGATCCGCACGGGGGAAT
TGACTGGTAAGTTAGATGAATGCTGCTTTGAACTGGCGCGTCAGCAAAAAGCCCAGCGTCAGTTGACCGACAAAGTGAAA
TCAGCGTTACGTTATCCCATTATCATTTTAGCGATGGCAATCATGGTGGTTGTGGCAATGCTGCATTTTGTGCTGCCGGA
GTTTGCTGCTATTTATAAAACCTTCAACACCCCACTACCGGCGCTAACGCAGGGGATCATGACGCTGGCAAGCTTTAGTG
GCGAATGGGGTTGGTTGCTGGTGCTATTCGGCTTTCTGCTGGCGATAGCCAATAAGCTGCTGATGCGCCACCCAACCAGG
CTTATCGCACGGCAGAAATTGCTGTTACGCATCCCGATTATGGGTTCACTGATGCGGGGACAAAAACTCACGCAGATCTT
TACGATTCTGGCGCTGACACAAAGTGCAGGCATTACTTTTTTACAGGGCGTTGAGAGCGTCAGAGAAACAATGCGCTGCC
CGTACTGGGTGCAACTTCTGACACAAATCCAGCACGATATCAGTAACGGTCATCCCATCTGGCTGGCGCTAAAAAATACC
GGGGAGTTTAGCCCGCTCTGTTTGCAATTAGTGAGAACAGGAGAGGCATCCGGCTCGCTGGATCTCATGTTAGACAACCT
CGCCCATCATCATCGGGATAACACACTGGCGCTGGCGGATAACCTCGCAGCCTTACTGGAACCGGCGTTGCTGATCATAA
CGGGAGGAATTATCGGTACGCTGGTGGTGGCAATGTATCTGCCAATTTTCCATTTAGGCGATGCGATGAGTGGAATGGGA
TAA

Upstream 100 bases:

>100_bases
CGACAGGCGGGTATGCGTACGCTTTTTGAAAACGGCTGCCTGGCCGTGGAGCAAGGCTTAACCACCTTTGAAGAGTTAAT
CCGCGTATTGGGGATGCCGC

Downstream 100 bases:

>100_bases
CGCTGGCGTGTTGCTCCACGCCAGCGTTGGGAGATTACAGGTTGTTGAAGATGCGGTTTTCTTGTTCCAGCACACGGATA
AATGTGGTGCGCTTGGTCAG

Product: type IV pilin biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MASKQLWRWHGITGDGNAQDGMLWAESRALLLIALQQQMVTPLSLKRIAINSAQWRGDKSAEVIHQLATLLKAGLTLSEG
LALLAEQHSSKQWQALLQSLAYDLEQGIAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVK
SALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLASFSGEWGWLLVLFGFLLAIANKLLMRHPTR
LIARQKLLLRIPIMGSLMRGQKLTQIFTILALTQSAGITFLQGVESVRETMRCPYWVQLLTQIQHDISNGHPIWLALKNT
GEFSPLCLQLVRTGEASGSLDLMLDNLAHHHRDNTLALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHLGDAMSGMG

Sequences:

>Translated_400_residues
MASKQLWRWHGITGDGNAQDGMLWAESRALLLIALQQQMVTPLSLKRIAINSAQWRGDKSAEVIHQLATLLKAGLTLSEG
LALLAEQHSSKQWQALLQSLAYDLEQGIAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVK
SALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLASFSGEWGWLLVLFGFLLAIANKLLMRHPTR
LIARQKLLLRIPIMGSLMRGQKLTQIFTILALTQSAGITFLQGVESVRETMRCPYWVQLLTQIQHDISNGHPIWLALKNT
GEFSPLCLQLVRTGEASGSLDLMLDNLAHHHRDNTLALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHLGDAMSGMG
>Mature_399_residues
ASKQLWRWHGITGDGNAQDGMLWAESRALLLIALQQQMVTPLSLKRIAINSAQWRGDKSAEVIHQLATLLKAGLTLSEGL
ALLAEQHSSKQWQALLQSLAYDLEQGIAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVKS
ALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLASFSGEWGWLLVLFGFLLAIANKLLMRHPTRL
IARQKLLLRIPIMGSLMRGQKLTQIFTILALTQSAGITFLQGVESVRETMRCPYWVQLLTQIQHDISNGHPIWLALKNTG
EFSPLCLQLVRTGEASGSLDLMLDNLAHHHRDNTLALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHLGDAMSGMG

Specific function: Unknown

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1786295, Length=400, Percent_Identity=97, Blast_Score=751, Evalue=0.0,
Organism=Escherichia coli, GI1789724, Length=405, Percent_Identity=25.679012345679, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 44261; Mature: 44130

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKQLWRWHGITGDGNAQDGMLWAESRALLLIALQQQMVTPLSLKRIAINSAQWRGDKS
CCCCCCHHEECCCCCCCCCCCEEECCCCHHHHHHHHHHHHCHHHHHHHHHCCHHCCCCCH
AEVIHQLATLLKAGLTLSEGLALLAEQHSSKQWQALLQSLAYDLEQGIAFSNALLPWSEV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHCCCCHHHH
FPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVKSALRYPIIILAMAIMVVVAM
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHFVLPEFAAIYKTFNTPLPALTQGIMTLASFSGEWGWLLVLFGFLLAIANKLLMRHPTR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHH
LIARQKLLLRIPIMGSLMRGQKLTQIFTILALTQSAGITFLQGVESVRETMRCPYWVQLL
HHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHH
TQIQHDISNGHPIWLALKNTGEFSPLCLQLVRTGEASGSLDLMLDNLAHHHRDNTLALAD
HHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHH
NLAALLEPALLIITGGIIGTLVVAMYLPIFHLGDAMSGMG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ASKQLWRWHGITGDGNAQDGMLWAESRALLLIALQQQMVTPLSLKRIAINSAQWRGDKS
CCCCCHHEECCCCCCCCCCCEEECCCCHHHHHHHHHHHHCHHHHHHHHHCCHHCCCCCH
AEVIHQLATLLKAGLTLSEGLALLAEQHSSKQWQALLQSLAYDLEQGIAFSNALLPWSEV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHCCCCHHHH
FPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVKSALRYPIIILAMAIMVVVAM
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHFVLPEFAAIYKTFNTPLPALTQGIMTLASFSGEWGWLLVLFGFLLAIANKLLMRHPTR
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHH
LIARQKLLLRIPIMGSLMRGQKLTQIFTILALTQSAGITFLQGVESVRETMRCPYWVQLL
HHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHH
TQIQHDISNGHPIWLALKNTGEFSPLCLQLVRTGEASGSLDLMLDNLAHHHRDNTLALAD
HHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHH
NLAALLEPALLIITGGIIGTLVVAMYLPIFHLGDAMSGMG
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7959070; 8202364; 9278503; 2904262 [H]