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The map label for this gene is gltS [H]

Identifier: 218698041

GI number: 218698041

Start: 4968992

End: 4969273

Strand: Reverse

Name: gltS [H]

Synonym: EC55989_4851

Alternate gene names: 218698041

Gene position: 4969273-4968992 (Counterclockwise)

Preceding gene: 218698042

Following gene: 218698039

Centisome position: 96.4

GC content: 39.36

Gene sequence:

>282_bases
ATGGTTACGTTTTGGGGAAATTATGAGGGGATCTCTCAGTGCTTTGTCACCTTCAAAATGATGGGCAAAGATTATGATGC
TGTCGTGATCAGCGCGGGTCACTGTGGCTTTGGTATGGGAGCAACACCAACAGCAATTGCGAATATGCAAACAGTCACAA
AAGCATTTGGACCATCACATAAAGCTTTCCTTGTCGTTCCTATGGTCGGTGCCTTTATTGTTGATATTTCAAACAGTATC
TTAATTAAAATATTTATTGAAATTGGTACATACTTTACCTAA

Upstream 100 bases:

>100_bases
GTTCGCTTAGGCATGGAAGTTTTGCGGCATTCTGGCTACACAATAACAAGGGAAGACTCACTCGTGGCTGCAACCCTGCT
TACTCAAAATCTATTCACAC

Downstream 100 bases:

>100_bases
TAGCTACACACTACTCGGCGTACTTCTCCTAACAATTTATTATAGGGCAGTATGCCGAGCCGCTTTCTTACCCCGTATAT
TCCCCTAGTCAATCTATTTA

Product: YdhA protein (fragment)

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 93; Mature: 93

Protein sequence:

>93_residues
MVTFWGNYEGISQCFVTFKMMGKDYDAVVISAGHCGFGMGATPTAIANMQTVTKAFGPSHKAFLVVPMVGAFIVDISNSI
LIKIFIEIGTYFT

Sequences:

>Translated_93_residues
MVTFWGNYEGISQCFVTFKMMGKDYDAVVISAGHCGFGMGATPTAIANMQTVTKAFGPSHKAFLVVPMVGAFIVDISNSI
LIKIFIEIGTYFT
>Mature_93_residues
MVTFWGNYEGISQCFVTFKMMGKDYDAVVISAGHCGFGMGATPTAIANMQTVTKAFGPSHKAFLVVPMVGAFIVDISNSI
LIKIFIEIGTYFT

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=72, Percent_Identity=70.8333333333333, Blast_Score=118, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 10054; Mature: 10054

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00134 TRYPSIN_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
6.5 %Met     (Translated Protein)
8.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
6.5 %Met     (Mature Protein)
8.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTFWGNYEGISQCFVTFKMMGKDYDAVVISAGHCGFGMGATPTAIANMQTVTKAFGPSH
CEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCC
KAFLVVPMVGAFIVDISNSILIKIFIEIGTYFT
CEEEEEEHHHHHEECCCCCEEEEEEEECCCCCC
>Mature Secondary Structure
MVTFWGNYEGISQCFVTFKMMGKDYDAVVISAGHCGFGMGATPTAIANMQTVTKAFGPSH
CEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCC
KAFLVVPMVGAFIVDISNSILIKIFIEIGTYFT
CEEEEEEHHHHHEECCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]