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The map label for this gene is dinF

Identifier: 218697752

GI number: 218697752

Start: 4649600

End: 4651000

Strand: Direct

Name: dinF

Synonym: EC55989_4537

Alternate gene names: 218697752

Gene position: 4649600-4651000 (Clockwise)

Preceding gene: 218697751

Following gene: 218697753

Centisome position: 90.2

GC content: 55.17

Gene sequence:

>1401_bases
ATGCCGCCAGGCGTCGCGGTTTGTTTTTCATCTCTCTTCATCAGGCTTGTCTGCATGGCATTCCTCACTTCATCTGATAA
AGCACTCTGGCATCTCGCCTTACCCATGATTTTCTCCAATATCACCGTTCCGTTGCTGGGACTGGTCGATACGGCGGTAA
TTGGTCATCTTGATAGCCCGGTTTATTTGGGCGGCGTGGCGGTTGGTGCAACGGCGACCAGCTTTCTCTTTATGCTGTTG
CTGTTTTTACGCATGAGCACCACCGGGCTGACTGCGCAGGCTTATGGTGCCAAAAATCCTCAGGCATTAGCCCGTGCGCT
GGTGCAACCGTTGCTGTTGGCGTTGGGGGCTGGGGCGTTAATTGCGCTGCTGCGTACACCGATTATCGATCTGGCGCTGC
ATATTGTTGGCGGTAGTGAAGCGGTCCTGGAACAGGCGCGGCGCTTTCTTGAAATCCGCTGGTTAAGCGCTCCGGCGTCG
CTGGCGAATCTGGTATTACTCGGTTGGTTACTCGGCGTGCAATATGCCCGTGCGCCAGTAATTTTGTTAGTGGTCGGCAA
TATCCTCAACATTGTGCTGGATGTCTGGCTGGTGATAGGGCTGCATATGAACGTGCAGGGCGCGGCGCTGGCGACGGTTA
TTGCGGAATATGCAACATTGCTGATTGGTCTGCTAATGGTGCGTAAAATCCTCAAACTACGCGGAATTTCCGGCGAAATG
CTGAAAACTGCCTGGCGAGGAAACTTCCGTCGCTTGCTGGCGCTTAACCGCGATATCATGCTGCGTTCGCTGTTGTTGCA
ACTCTGTTTCGGCGTGATCACCGTACTTGGTGCGCGACTGGGGAGTGACATTATCGCTGTTAACGCGGTTCTGATGACGC
TACTCACCTTCACCGCCTATGCGCTGGATGGTTTTGCCTACGCGGTTGAAGCACATTCCGGTCAGGCATACGGTGCGCGC
GACGGTAGCCAGTTGCTGGATGTCTGGCGGGCAGCGTGCCGCCAGTCGGGGATCGTAGCGCTACTGTTTTCGGTGGTTTA
TTTGCTGGCAGGGGAACACATCATTGCGTTACTGACGTCGTTAACCCAGATTCAGGAGCTGGCCGACCGCTATCTTATCT
GGCAGGTGATTTTGCCGTTGGTTGGAGTCTGGTGTTATCTGCTGGACGGCATGTTTATAGGCGCAACGCGTGCCGCCGAA
ATGCGTAACAGTATGGCGGTGGCCGCCGCAGGTTTTGCGCTGACGCTCCTTACGCTGCCGTGGCTGGGTAATCATGGTTT
GTGGCTGGCATTAACCGTCTTTCTGGCGTTGCGCGGGCTTTCTCTGGCGGCTATCTGGCGGGCGTCACTGGCGCAACGGT
ACCTGGTTTGCCGCAACGTGACGGTTAAAAATTCTGAATAA

Upstream 100 bases:

>100_bases
AATTGTCGTTGACCTTCGTCAGCAGAGCTTCACCATTGAAGGGCTGGCGGTTGGGGTTATTCGCAACGGCGACTGGCTGT
AACATATCTCTGAGACCGCG

Downstream 100 bases:

>100_bases
ATAATCCTAAGCCAAATTGCTGACTACACTTAATCTCACGTTCAGAAGAAAAGTGAACGTACTCTCATTCACAACCTAAC
GATGAGGTCTTGATTATGAA

Product: DNA-damage-inducible SOS response protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MPPGVAVCFSSLFIRLVCMAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFMLL
LFLRMSTTGLTAQAYGAKNPQALARALVQPLLLALGAGALIALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPAS
LANLVLLGWLLGVQYARAPVILLVVGNILNIVLDVWLVIGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGISGEM
LKTAWRGNFRRLLALNRDIMLRSLLLQLCFGVITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGAR
DGSQLLDVWRAACRQSGIVALLFSVVYLLAGEHIIALLTSLTQIQELADRYLIWQVILPLVGVWCYLLDGMFIGATRAAE
MRNSMAVAAAGFALTLLTLPWLGNHGLWLALTVFLALRGLSLAAIWRASLAQRYLVCRNVTVKNSE

Sequences:

>Translated_466_residues
MPPGVAVCFSSLFIRLVCMAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFMLL
LFLRMSTTGLTAQAYGAKNPQALARALVQPLLLALGAGALIALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPAS
LANLVLLGWLLGVQYARAPVILLVVGNILNIVLDVWLVIGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGISGEM
LKTAWRGNFRRLLALNRDIMLRSLLLQLCFGVITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGAR
DGSQLLDVWRAACRQSGIVALLFSVVYLLAGEHIIALLTSLTQIQELADRYLIWQVILPLVGVWCYLLDGMFIGATRAAE
MRNSMAVAAAGFALTLLTLPWLGNHGLWLALTVFLALRGLSLAAIWRASLAQRYLVCRNVTVKNSE
>Mature_465_residues
PPGVAVCFSSLFIRLVCMAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFMLLL
FLRMSTTGLTAQAYGAKNPQALARALVQPLLLALGAGALIALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPASL
ANLVLLGWLLGVQYARAPVILLVVGNILNIVLDVWLVIGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGISGEML
KTAWRGNFRRLLALNRDIMLRSLLLQLCFGVITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARD
GSQLLDVWRAACRQSGIVALLFSVVYLLAGEHIIALLTSLTQIQELADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEM
RNSMAVAAAGFALTLLTLPWLGNHGLWLALTVFLALRGLSLAAIWRASLAQRYLVCRNVTVKNSE

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=447, Percent_Identity=98.4340044742729, Blast_Score=858, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 50247; Mature: 50116

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPGVAVCFSSLFIRLVCMAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSP
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VYLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAKNPQALARALVQPLLLALGAGAL
CEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
IALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHH
ILLVVGNILNIVLDVWLVIGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGISGEM
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LKTAWRGNFRRLLALNRDIMLRSLLLQLCFGVITVLGARLGSDIIAVNAVLMTLLTFTAY
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
ALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGIVALLFSVVYLLAGEHIIALLTS
HHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHH
LTQIQELADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAAGFALTLLTLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLGNHGLWLALTVFLALRGLSLAAIWRASLAQRYLVCRNVTVKNSE
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEECCCC
>Mature Secondary Structure 
PPGVAVCFSSLFIRLVCMAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSP
CCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VYLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAKNPQALARALVQPLLLALGAGAL
CEECCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
IALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARAPV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHH
ILLVVGNILNIVLDVWLVIGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGISGEM
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LKTAWRGNFRRLLALNRDIMLRSLLLQLCFGVITVLGARLGSDIIAVNAVLMTLLTFTAY
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
ALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGIVALLFSVVYLLAGEHIIALLTS
HHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHH
LTQIQELADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAAGFALTLLTLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLGNHGLWLALTVFLALRGLSLAAIWRASLAQRYLVCRNVTVKNSE
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]