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The map label for this gene is polA

Identifier: 218697577

GI number: 218697577

Start: 4430664

End: 4433450

Strand: Direct

Name: polA

Synonym: EC55989_4339

Alternate gene names: 218697577

Gene position: 4430664-4433450 (Clockwise)

Preceding gene: 218697575

Following gene: 218697579

Centisome position: 85.95

GC content: 52.28

Gene sequence:

>2787_bases
ATGGTTCAGATCCCCCAAAATCCACTTATCCTTGTAGATGGTTCATCTTATCTTTATCGCGCATATCACGCGTTTCCCCC
GCTGACTAACAGCGCAGGCGAGCCGACCGGTGCGATGTATGGTGTCCTCAACATGCTGCGCAGTCTGATCATGCAATATA
AACCGACGCATGCAGCGGTGGTCTTTGACGCCAAGGGAAAAACCTTTCGTGATGAACTGTTTGAACATTACAAATCACAT
CGCCCGCCAATGCCGGACGATCTGCGAGCACAAATCGAACCTCTGCACGCGATGGTTAAAGCGATGGGACTGCCGCTGCT
GGCGGTTTCTGGCGTAGAAGCGGACGACGTTATCGGTACTCTGGCGCGCGAAGCCGAAAAAGCCGGGCGTCCGGTGCTGA
TCAGCACTGGCGATAAAGATATGGCGCAGCTGGTGACGCCAAATATTACGCTTATCAATACCATGACGAATACCATCCTC
GGACCGGAAGAGGTGGTGAATAAGTACGGCGTGCCGCCAGAACTGATCATCGATTTCCTGGCGCTGATGGGTGACTCCTC
CGATAACATCCCTGGCGTACCGGGCGTCGGTGAAAAAACCGCGCAGGCATTGCTGCAAGGTCTGGGCGGGCTGGATACGC
TGTATGCCGAGCCAGAAAAAATTGCTGGGTTGAGCTTCCGTGGCGCGAAAACAATGGCAGCGAAGCTCGAGCAAAACAAA
GAAGTTGCTTATCTCTCATACCAGCTGGCGACGATTAAAACCGACGTTGAACTGGAGCTGACCTGTGAACAACTGGAAGT
GCAGCAACCGGCAGCGGAAGAGTTGTTGGGGCTGTTCAAAAAGTATGAGTTCAAACGCTGGACTGCTGATGTCGAAGCGG
GCAAATGGTTACAGGCCAAAGGGGCAAAACCAGCCGCGAAGCCGCAGGAAACCAGTGTTGCAGACGAAGCGCCAGAAGTG
ACGGCAACGGTGATTTCTTATGACAACTACGTCACCATCCTTGATGAAGAAACACTGAAAGCGTGGATTGCGAAGCTGGA
AAAAGCGCCGGTATTTGCATTTGATACCGAAACCGACAGCCTTGATAACATCTCTGCTAACCTGGTCGGGCTTTCTTTTG
CTATCGAGCCAGGCGTAGCGGCATATATTCCGGTTGCTCATGATTATCTTGATGCGCCCGATCAAATCTCTCGCGAGCGT
GCACTCGAGTTGCTAAAACCGCTGCTGGAAGATGAAAAGGCGCTGAAGGTCGGGCAAAACCTGAAATACGATCGCGGTAT
TCTGGCGAATTACGGCATTGAGCTGCGTGGGATTGCGTTTGATACCATGCTGGAGTCCTACATTCTCAATAGCGTTGCCG
GGCGTCACGATATGGACAGCCTCGCGGAACGTTGGTTGAAGCACAAAACCATCACTTTTGAAGAGATTGCGGGTAAAGGC
AAAAATCAACTGACCTTTAACCAGATTGCCCTCGAAGAGGCCGGACGTTACGCCGCCGAAGATGCTGATGTCACCTTGCA
GTTGCATCTGAAAATGTGGCCGGACCTGCAAAAACACAAAGGGCCGTTGAACGTCTTCGAGAATATCGAAATGCCGCTGG
TGCCGGTGCTTTCACGCATTGAACGTAACGGTGTGAAGATCGATCCGAAAGTGCTGCACAATCATTCTGAAGAGCTCACC
TTGCGTCTGGCTGAGCTGGAAAAGAAAGCGCATGAAATTGCAGGTGAAGAATTTAACCTTTCTTCCACCAAGCAGTTGCA
AACCATTCTGTTTGAAAAACAGGGTATTAAACCGCTGAAGAAAACGCCGGGTGGCGCGCCGTCAACGTCGGAAGAGGTAC
TGGAAGAACTGGCGCTGGACTATCCGTTGCCAAAAGTGATTCTGGAGTATCGTGGTCTGGCGAAGCTGAAATCGACCTAC
ACCGACAAGCTGCCGCTGATGATCAACCCGAAAACCGGGCGTGTGCATACCTCTTATCACCAGGCAGTAACTGCAACGGG
ACGTTTATCGTCAACCGATCCTAACCTGCAAAACATTCCGGTGCGTAACGAAGAAGGTCGTCGTATCCGCCAGGCGTTTA
TTGCGCCAGAGGATTATGTGATTGTCTCAGCGGACTACTCGCAGATTGAACTGCGCATTATGGCGCATCTCTCGCGTGAC
AAAGGCTTGCTGACCGCATTCGCGGAAGGAAAAGATATCCACCGGGCAACGGCGGCAGAAGTGTTTGGTTTGCCACTGGA
AACCGTCACCAGCGAGCAACGCCGTAGCGCGAAAGCGATCAACTTTGGTCTGATTTATGGCATGAGTGCTTTCGGTCTGG
CGCGGCAATTGAACATTCCACGTAAAGAAGCGCAGAAGTACATGGACCTTTACTTCGAACGCTACCCTGGCGTGCTGGAG
TATATGGAACGCACCCGTGCTCAGGCGAAAGAGCAGGGCTACGTTGAAACGCTGGACGGACGCCGTCTGTATCTGCCGGA
TATCAAATCCAGCAATGGTGCTCGTCGTGCAGCGGCTGAACGTGCAGCCATTAACGCGCCAATGCAGGGAACCGCCGCCG
ACATTATCAAACGGGCGATGATTGCCGTTGATGCGTGGTTACAGGCTGAGCAACCGCGTGTACGTATGATCATGCAGGTA
CACGATGAACTGGTATTTGAAGTTCATAAAGATGATGTTGATGCCGTCGCGAAGCAGATTCATCAACTGATGGAAAACTG
TACCCGTCTGGATGTGCCGTTGCTGGTGGAAGTGGGGAGTGGCGAAAACTGGGATCAGGCGCACTAA

Upstream 100 bases:

>100_bases
AGATCTACAAAAGATTTTCACGAAAAGCGGTGAAAAACTCATGTTTTTATCCTGTCTGTGGCATCCTTTACCCATAATCT
GATAAACAGGCACGGACATT

Downstream 100 bases:

>100_bases
GATTCGCCTGAACATGCCCTTTTTTCGTAAGTAAGCAACATAAGCTGTCACGTTTTGTGATGGCTATTAGAAATTCCTAT
GCAACAACTGAAAAAAAATT

Product: DNA polymerase I

Products: NA

Alternate protein names: POL I

Number of amino acids: Translated: 928; Mature: 928

Protein sequence:

>928_residues
MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLIMQYKPTHAAVVFDAKGKTFRDELFEHYKSH
RPPMPDDLRAQIEPLHAMVKAMGLPLLAVSGVEADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPNITLINTMTNTIL
GPEEVVNKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEPEKIAGLSFRGAKTMAAKLEQNK
EVAYLSYQLATIKTDVELELTCEQLEVQQPAAEELLGLFKKYEFKRWTADVEAGKWLQAKGAKPAAKPQETSVADEAPEV
TATVISYDNYVTILDEETLKAWIAKLEKAPVFAFDTETDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDAPDQISRER
ALELLKPLLEDEKALKVGQNLKYDRGILANYGIELRGIAFDTMLESYILNSVAGRHDMDSLAERWLKHKTITFEEIAGKG
KNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPDLQKHKGPLNVFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELT
LRLAELEKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTY
TDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRD
KGLLTAFAEGKDIHRATAAEVFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGVLE
YMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAERAAINAPMQGTAADIIKRAMIAVDAWLQAEQPRVRMIMQV
HDELVFEVHKDDVDAVAKQIHQLMENCTRLDVPLLVEVGSGENWDQAH

Sequences:

>Translated_928_residues
MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLIMQYKPTHAAVVFDAKGKTFRDELFEHYKSH
RPPMPDDLRAQIEPLHAMVKAMGLPLLAVSGVEADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPNITLINTMTNTIL
GPEEVVNKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEPEKIAGLSFRGAKTMAAKLEQNK
EVAYLSYQLATIKTDVELELTCEQLEVQQPAAEELLGLFKKYEFKRWTADVEAGKWLQAKGAKPAAKPQETSVADEAPEV
TATVISYDNYVTILDEETLKAWIAKLEKAPVFAFDTETDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDAPDQISRER
ALELLKPLLEDEKALKVGQNLKYDRGILANYGIELRGIAFDTMLESYILNSVAGRHDMDSLAERWLKHKTITFEEIAGKG
KNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPDLQKHKGPLNVFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELT
LRLAELEKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTY
TDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRD
KGLLTAFAEGKDIHRATAAEVFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGVLE
YMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAERAAINAPMQGTAADIIKRAMIAVDAWLQAEQPRVRMIMQV
HDELVFEVHKDDVDAVAKQIHQLMENCTRLDVPLLVEVGSGENWDQAH
>Mature_928_residues
MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLIMQYKPTHAAVVFDAKGKTFRDELFEHYKSH
RPPMPDDLRAQIEPLHAMVKAMGLPLLAVSGVEADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPNITLINTMTNTIL
GPEEVVNKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEPEKIAGLSFRGAKTMAAKLEQNK
EVAYLSYQLATIKTDVELELTCEQLEVQQPAAEELLGLFKKYEFKRWTADVEAGKWLQAKGAKPAAKPQETSVADEAPEV
TATVISYDNYVTILDEETLKAWIAKLEKAPVFAFDTETDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDAPDQISRER
ALELLKPLLEDEKALKVGQNLKYDRGILANYGIELRGIAFDTMLESYILNSVAGRHDMDSLAERWLKHKTITFEEIAGKG
KNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPDLQKHKGPLNVFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELT
LRLAELEKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTY
TDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRD
KGLLTAFAEGKDIHRATAAEVFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGVLE
YMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAERAAINAPMQGTAADIIKRAMIAVDAWLQAEQPRVRMIMQV
HDELVFEVHKDDVDAVAKQIHQLMENCTRLDVPLLVEVGSGENWDQAH

Specific function: In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity. It is able to utilize nicked circular duplex DNA as a template and can unwind the parental DNA strand from its template

COG id: COG0749

COG function: function code L; DNA polymerase I - 3'-5' exonuclease and polymerase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 5'-3' exonuclease domain

Homologues:

Organism=Homo sapiens, GI112420958, Length=519, Percent_Identity=31.2138728323699, Blast_Score=246, Evalue=7e-65,
Organism=Homo sapiens, GI139394648, Length=269, Percent_Identity=38.2899628252788, Blast_Score=177, Evalue=3e-44,
Organism=Escherichia coli, GI1790294, Length=928, Percent_Identity=100, Blast_Score=1902, Evalue=0.0,
Organism=Escherichia coli, GI226510970, Length=261, Percent_Identity=31.8007662835249, Blast_Score=132, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI86563272, Length=406, Percent_Identity=29.3103448275862, Blast_Score=183, Evalue=4e-46,
Organism=Drosophila melanogaster, GI17933644, Length=419, Percent_Identity=33.6515513126492, Blast_Score=222, Evalue=7e-58,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): DPO1_ECOLI (P00582)

Other databases:

- EMBL:   V00317
- EMBL:   L19201
- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   J01663
- EMBL:   J01664
- PIR:   A92360
- RefSeq:   AP_003944.1
- RefSeq:   NP_418300.1
- PDB:   1D8Y
- PDB:   1D9D
- PDB:   1D9F
- PDB:   1DPI
- PDB:   1KFD
- PDB:   1KFS
- PDB:   1KLN
- PDB:   1KRP
- PDB:   1KSP
- PDB:   1QSL
- PDB:   2KFN
- PDB:   2KFZ
- PDB:   2KZM
- PDB:   2KZZ
- PDBsum:   1D8Y
- PDBsum:   1D9D
- PDBsum:   1D9F
- PDBsum:   1DPI
- PDBsum:   1KFD
- PDBsum:   1KFS
- PDBsum:   1KLN
- PDBsum:   1KRP
- PDBsum:   1KSP
- PDBsum:   1QSL
- PDBsum:   2KFN
- PDBsum:   2KFZ
- PDBsum:   2KZM
- PDBsum:   2KZZ
- ProteinModelPortal:   P00582
- SMR:   P00582
- DIP:   DIP-10524N
- IntAct:   P00582
- MINT:   MINT-1225247
- STRING:   P00582
- SWISS-2DPAGE:   P00582
- PRIDE:   P00582
- EnsemblBacteria:   EBESCT00000001399
- EnsemblBacteria:   EBESCT00000014390
- GeneID:   948356
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW3835
- KEGG:   eco:b3863
- EchoBASE:   EB0739
- EcoGene:   EG10746
- eggNOG:   COG0749
- GeneTree:   EBGT00050000009637
- HOGENOM:   HBG284758
- OMA:   IPIRTEE
- ProtClustDB:   PRK05755
- BioCyc:   EcoCyc:EG10746-MONOMER
- BioCyc:   MetaCyc:EG10746-MONOMER
- Genevestigator:   P00582
- GO:   GO:0005622
- InterPro:   IPR002562
- InterPro:   IPR020046
- InterPro:   IPR020045
- InterPro:   IPR002421
- InterPro:   IPR020047
- InterPro:   IPR019760
- InterPro:   IPR001098
- InterPro:   IPR018320
- InterPro:   IPR002298
- InterPro:   IPR008918
- InterPro:   IPR003583
- InterPro:   IPR012337
- PRINTS:   PR00868
- SMART:   SM00474
- SMART:   SM00475
- SMART:   SM00278
- SMART:   SM00279
- SMART:   SM00482
- TIGRFAMs:   TIGR00593

Pfam domain/function: PF01612 3_5_exonuc; PF01367 5_3_exonuc; PF02739 5_3_exonuc_N; PF00476 DNA_pol_A; SSF47807 5_3_exo_C; SSF53098 RNaseH_fold

EC number: =2.7.7.7

Molecular weight: Translated: 103119; Mature: 103119

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00447 DNA_POLYMERASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLIMQYKPTHAAV
CCCCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
VFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAMGLPLLAVSGVEADDVIGT
EEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHH
LAREAEKAGRPVLISTGDKDMAQLVTPNITLINTMTNTILGPEEVVNKYGVPPELIIDFL
HHHHHHHCCCCEEEECCCHHHHHHHCCCEEEEECHHHHCCCHHHHHHHCCCCHHHHHHHH
ALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEPEKIAGLSFRGAKTMAAKLEQNK
HHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCHHHHCCCCCCCHHHHHHHHHCCC
EVAYLSYQLATIKTDVELELTCEQLEVQQPAAEELLGLFKKYEFKRWTADVEAGKWLQAK
CEEEEEEEEEEEEECCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
GAKPAAKPQETSVADEAPEVTATVISYDNYVTILDEETLKAWIAKLEKAPVFAFDTETDS
CCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEECHHHHHHHHHHHHCCCEEEECCCCCC
LDNISANLVGLSFAIEPGVAAYIPVAHDYLDAPDQISRERALELLKPLLEDEKALKVGQN
CCCCCCEEEEEEEEECCCCEEEECCHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCC
LKYDRGILANYGIELRGIAFDTMLESYILNSVAGRHDMDSLAERWLKHKTITFEEIAGKG
CCCCCCHHHHCCEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHCCC
KNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPDLQKHKGPLNVFENIEMPLVPVLSRI
CCCEEHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHCCCCCHHHHCCCCCHHHHHHHH
ERNGVKIDPKVLHNHSEELTLRLAELEKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLK
HHCCCEECHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHH
KTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKLPLMINPKTGRVHTSYH
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEECHHH
QAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRD
HHHEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCC
KGLLTAFAEGKDIHRATAAEVFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIP
CCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RKEAQKYMDLYFERYPGVLEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEECCCCEEECCCCCCCCCHHHHHHH
RAAINAPMQGTAADIIKRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHKDDVDAVAKQI
HHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
HQLMENCTRLDVPLLVEVGSGENWDQAH
HHHHHHHHHCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLNMLRSLIMQYKPTHAAV
CCCCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
VFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAMGLPLLAVSGVEADDVIGT
EEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHH
LAREAEKAGRPVLISTGDKDMAQLVTPNITLINTMTNTILGPEEVVNKYGVPPELIIDFL
HHHHHHHCCCCEEEECCCHHHHHHHCCCEEEEECHHHHCCCHHHHHHHCCCCHHHHHHHH
ALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEPEKIAGLSFRGAKTMAAKLEQNK
HHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHCCHHHHCCCCCCCHHHHHHHHHCCC
EVAYLSYQLATIKTDVELELTCEQLEVQQPAAEELLGLFKKYEFKRWTADVEAGKWLQAK
CEEEEEEEEEEEEECCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
GAKPAAKPQETSVADEAPEVTATVISYDNYVTILDEETLKAWIAKLEKAPVFAFDTETDS
CCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEECHHHHHHHHHHHHCCCEEEECCCCCC
LDNISANLVGLSFAIEPGVAAYIPVAHDYLDAPDQISRERALELLKPLLEDEKALKVGQN
CCCCCCEEEEEEEEECCCCEEEECCHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHCCC
LKYDRGILANYGIELRGIAFDTMLESYILNSVAGRHDMDSLAERWLKHKTITFEEIAGKG
CCCCCCHHHHCCEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHCCC
KNQLTFNQIALEEAGRYAAEDADVTLQLHLKMWPDLQKHKGPLNVFENIEMPLVPVLSRI
CCCEEHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHCCCCCHHHHCCCCCHHHHHHHH
ERNGVKIDPKVLHNHSEELTLRLAELEKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLK
HHCCCEECHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHH
KTPGGAPSTSEEVLEELALDYPLPKVILEYRGLAKLKSTYTDKLPLMINPKTGRVHTSYH
CCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCEECHHH
QAVTATGRLSSTDPNLQNIPVRNEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRD
HHHEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCC
KGLLTAFAEGKDIHRATAAEVFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIP
CCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RKEAQKYMDLYFERYPGVLEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEECCCCEEECCCCCCCCCHHHHHHH
RAAINAPMQGTAADIIKRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHKDDVDAVAKQI
HHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHH
HQLMENCTRLDVPLLVEVGSGENWDQAH
HHHHHHHHHCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6276402; 8346018; 9278503; 6183253; 6302278; 7035456; 3883192; 1989886; 8469987; 8260491; 9514742; 9888810; 10588690; 8442659