Click here to switch to the map view.

The map label for this gene is yiaU

Identifier: 218697302

GI number: 218697302

Start: 4122569

End: 4123543

Strand: Direct

Name: yiaU

Synonym: EC55989_4042

Alternate gene names: 218697302

Gene position: 4122569-4123543 (Clockwise)

Preceding gene: 218697300

Following gene: 218697305

Centisome position: 79.97

GC content: 47.59

Gene sequence:

>975_bases
ATGACAAAATTACAACTTAAGTACCGGGAGTTAAAAATTATCTCGGTAATCGCTGCCAGTGAAAATATCAGCCATGCCGC
GACTGTACTTGGCATCGCACAGGCCAACGTCAGCAAATATCTTGCTGATTTTGAATCAAAAGTGGGTTTAAAAGTTTTTG
ACCGAACCACCCGGCAGCTGATGCTCACACCTTTTGGCACCGCGCTGTTACCGTACATCAACGACATGCTGGACAGAAAC
GAGCAACTTAATAATTTTATTGCAGATTATAAGCATGAGAAACGTGGTCGGGTCACCATCTACGCCCCAACCGGCATAAT
TACCTATTTATCCAAACATGTAATCGATAAAATTAAAGATATCGGTGATATCACCTTATCGCTAAAAACCTGCAATCTTG
AGCGTAATGCCTTTTATGAAGGCGTCGAATTTCCTGATGATTGTGATGTTTTAATCAGCTACGCTCCACCAAAAGATGAA
TCGCTGGTTGCCAGTTTTATTACCCAATATGCCGTAACCGCTTATGCCAGCCAGCGCTATCTTGAGAAACATCCCATTAG
CCGTCCTGACGAACTCGAACATCACTCCTGTATTTTGATCGACTCGATGATGATCGACGACGCGAATATCTGGCGCTTCA
ACGTCGCCGGGAGTAAAGAGGTGCGGGATTATCGCGTGAAGGGAAATTACGTTTGCGACAACACGCAATCTGCGCTGGAG
CTGGCACGAAATCACCTGGGGATTGTGTTTGCGCCAGACAAAAGTGTGCAGAGCGACCTGCAAGACGGCACGCTGGTGCC
CTGCTTTCAGCAACCCTATGAATGGTGGCTGGATCTGGTGGCTATCTTCCGTAAACGGGAATACCAGCCCTGGCGGGTCC
AGTATGTGCTGGATGAAATGCTGCGTGAAATTCGCCACCAGCTTGCTCAGTCGCAGCAACTGCGGCCTGAACAAGCGGCG
GAAAGCGAAGATTAA

Upstream 100 bases:

>100_bases
AGATAAAAAAGAGTCGGCATAATAATGCTTACAATTTCTCCGGTGCAAGATTCATATTTATATAGTAATATATAAAATTA
TATATAATTGGGCTGTTGCG

Downstream 100 bases:

>100_bases
TGATCGAGATAAAGGTAATGCACCCAGCTGGTCATGCGTAATAGCACTTTGCGCATCACCGAGACATGGCTGAAATGATC
AGAGTAAACCGCCACCTGGG

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTKLQLKYRELKIISVIAASENISHAATVLGIAQANVSKYLADFESKVGLKVFDRTTRQLMLTPFGTALLPYINDMLDRN
EQLNNFIADYKHEKRGRVTIYAPTGIITYLSKHVIDKIKDIGDITLSLKTCNLERNAFYEGVEFPDDCDVLISYAPPKDE
SLVASFITQYAVTAYASQRYLEKHPISRPDELEHHSCILIDSMMIDDANIWRFNVAGSKEVRDYRVKGNYVCDNTQSALE
LARNHLGIVFAPDKSVQSDLQDGTLVPCFQQPYEWWLDLVAIFRKREYQPWRVQYVLDEMLREIRHQLAQSQQLRPEQAA
ESED

Sequences:

>Translated_324_residues
MTKLQLKYRELKIISVIAASENISHAATVLGIAQANVSKYLADFESKVGLKVFDRTTRQLMLTPFGTALLPYINDMLDRN
EQLNNFIADYKHEKRGRVTIYAPTGIITYLSKHVIDKIKDIGDITLSLKTCNLERNAFYEGVEFPDDCDVLISYAPPKDE
SLVASFITQYAVTAYASQRYLEKHPISRPDELEHHSCILIDSMMIDDANIWRFNVAGSKEVRDYRVKGNYVCDNTQSALE
LARNHLGIVFAPDKSVQSDLQDGTLVPCFQQPYEWWLDLVAIFRKREYQPWRVQYVLDEMLREIRHQLAQSQQLRPEQAA
ESED
>Mature_323_residues
TKLQLKYRELKIISVIAASENISHAATVLGIAQANVSKYLADFESKVGLKVFDRTTRQLMLTPFGTALLPYINDMLDRNE
QLNNFIADYKHEKRGRVTIYAPTGIITYLSKHVIDKIKDIGDITLSLKTCNLERNAFYEGVEFPDDCDVLISYAPPKDES
LVASFITQYAVTAYASQRYLEKHPISRPDELEHHSCILIDSMMIDDANIWRFNVAGSKEVRDYRVKGNYVCDNTQSALEL
ARNHLGIVFAPDKSVQSDLQDGTLVPCFQQPYEWWLDLVAIFRKREYQPWRVQYVLDEMLREIRHQLAQSQQLRPEQAAE
SED

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790011, Length=324, Percent_Identity=100, Blast_Score=676, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): YIAU_ECOLI (P37682)

Other databases:

- EMBL:   U00039
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   S47806
- RefSeq:   AP_004207.1
- RefSeq:   NP_418042.1
- ProteinModelPortal:   P37682
- SMR:   P37682
- DIP:   DIP-12411N
- STRING:   P37682
- EnsemblBacteria:   EBESCT00000003445
- EnsemblBacteria:   EBESCT00000017663
- GeneID:   948107
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW3557
- KEGG:   eco:b3585
- EchoBASE:   EB2197
- EcoGene:   EG12289
- eggNOG:   COG0583
- GeneTree:   EBGT00050000008335
- HOGENOM:   HBG467397
- OMA:   TEFGEQF
- ProtClustDB:   CLSK880731
- BioCyc:   EcoCyc:EG12289-MONOMER
- Genevestigator:   P37682
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate

EC number: NA

Molecular weight: Translated: 37275; Mature: 37144

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLQLKYRELKIISVIAASENISHAATVLGIAQANVSKYLADFESKVGLKVFDRTTRQL
CCCEEEEHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHE
MLTPFGTALLPYINDMLDRNEQLNNFIADYKHEKRGRVTIYAPTGIITYLSKHVIDKIKD
EECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHC
IGDITLSLKTCNLERNAFYEGVEFPDDCDVLISYAPPKDESLVASFITQYAVTAYASQRY
CCCEEEEEEEECCCHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
LEKHPISRPDELEHHSCILIDSMMIDDANIWRFNVAGSKEVRDYRVKGNYVCDNTQSALE
HHHCCCCCCCCCCCCCEEEEEEEEECCCCEEEEECCCCCCCCEEEECCCEEECCHHHHHH
LARNHLGIVFAPDKSVQSDLQDGTLVPCFQQPYEWWLDLVAIFRKREYQPWRVQYVLDEM
HHHHCCCEEECCCHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LREIRHQLAQSQQLRPEQAAESED
HHHHHHHHHHHHCCCCHHHCCCCC
>Mature Secondary Structure 
TKLQLKYRELKIISVIAASENISHAATVLGIAQANVSKYLADFESKVGLKVFDRTTRQL
CCEEEEHHHEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHE
MLTPFGTALLPYINDMLDRNEQLNNFIADYKHEKRGRVTIYAPTGIITYLSKHVIDKIKD
EECCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHC
IGDITLSLKTCNLERNAFYEGVEFPDDCDVLISYAPPKDESLVASFITQYAVTAYASQRY
CCCEEEEEEEECCCHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
LEKHPISRPDELEHHSCILIDSMMIDDANIWRFNVAGSKEVRDYRVKGNYVCDNTQSALE
HHHCCCCCCCCCCCCCEEEEEEEEECCCCEEEEECCCCCCCCEEEECCCEEECCHHHHHH
LARNHLGIVFAPDKSVQSDLQDGTLVPCFQQPYEWWLDLVAIFRKREYQPWRVQYVLDEM
HHHHCCCEEECCCHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LREIRHQLAQSQQLRPEQAAESED
HHHHHHHHHHHHCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503