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The map label for this gene is yhjE

Identifier: 218697232

GI number: 218697232

Start: 4039895

End: 4041217

Strand: Direct

Name: yhjE

Synonym: EC55989_3969

Alternate gene names: 218697232

Gene position: 4039895-4041217 (Clockwise)

Preceding gene: 218697231

Following gene: 218697235

Centisome position: 78.37

GC content: 55.86

Gene sequence:

>1323_bases
ATGCAAGCAACAGCCACAACACTCGACCACGAGCAAGAATACACGCCGATCAACTCGCGTAATAAAGTCCTTGTCGCCTC
TCTCATTGGCACGGCCATTGAGTTCTTCGACTTTTACATTTACGCCACTGCGGCCGTTATTGTGTTTCCGCATATCTTCT
TCCCACAGGGCGATCCAACGGCAGCAACGCTACAGTCGCTCGCCACCTTCGCCATCGCCTTCGTCGCGCGCCCCATTGGC
TCTGCCGTTTTTGGTCATTTTGGCGATCGCGTTGGGCGTAAAGCGACGCTGGTCGCCTCGTTGCTAACGATGGGGATTTC
GACCGTGGTGATTGGTCTGCTGCCGGGCTATGCCACGATTGGTATTTTCGCCCCACTGCTGCTGGCGCTGGCTCGATTTG
GTCAGGGTCTGGGCTTAGGCGGTGAATGGGGCGGCGCGGCGCTGCTGGCGACTGAAAACGCCCCACCGCGCAAACGTGCA
CTGTATGGCTCCTTCCCACAGCTGGGCGCACCGATTGGCTTCTTCTTTGCCAACGGCACTTTCTTGCTGCTTTCCTGGCT
ACTGACCGATGAGCAGTTTATGAGCTGGGGCTGGCGTGTGCCATTTATCTTCTCGGCGGTGCTGGTCATTATCGGCCTGT
ATGTTCGCGTGTCGCTGCATGAGTCGCCGGTGTTTGAGAAAGTCGCTAAAGCGAAAAAACAGGTGAAGATCCCGCTGGGT
ACGCTGCTGACCAAACATGTTCGCGTAACCGTACTGGGTACGTTCATCATGCTGGCAACATATACGCTGTTTTACATCAT
GACGGTCTACTCTATGACCTTCAGTACCGCCGCCGCGCCAGTTGGGCTTGGCCTGCCACGTAACGAAGTGTTGTGGATGC
TGATGATGGCAGTTATTGGTTTTGGCGTGATGGTGCCAGTCGCCGGATTACTGGCTGATGCCTTTGGTCGCCGTAAAAGC
ATGGTAATTATCACCACGCTGATCATCCTGTTCGCGCTGTTCGCCTTTAACCCGCTGCTCGGTTCTGGCAACCCGATTCT
GGTTTTTGCCTTCCTGCTGCTGGGGTTAAGTCTGATGGGGCTGACCTTCGGGCCAATGGGCGCGCTGTTACCAGAGCTGT
TCCCAACAGAAGTGCGTTACACCGGAGCATCGTTCTCTTACAACGTAGCGTCGATTCTCGGGGCTTCCGTTGCGCCGTAT
ATCGCAGCCTGGTTGCAGACTAACTACGGGTTAGGTGCGGTGGGGTTATATCTGGCGGCGATGGCTGGCTTGACGTTAAT
CGCCCTGCTGCTGACCCATGAGACGCGACATCAGTCGTTGTAA

Upstream 100 bases:

>100_bases
TGCCTGGTTTTTGACCATTTCCGCGATTTGTTACACATTGAAATATCACTTTTGCTGTGCGTAATATGGCTATTCGTTAG
CCAAAAAATAAGAAAAGATT

Downstream 100 bases:

>100_bases
GTATCGTGTGGGCAGCCACCCTCACCCCAGCCCTCTCCCTGAAAGGGAGAGGGAGAAAAGCGGAGCGAGATGTTATATCG
CGAACATAACAGCCCTCCCC

Product: putative transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MQATATTLDHEQEYTPINSRNKVLVASLIGTAIEFFDFYIYATAAVIVFPHIFFPQGDPTAATLQSLATFAIAFVARPIG
SAVFGHFGDRVGRKATLVASLLTMGISTVVIGLLPGYATIGIFAPLLLALARFGQGLGLGGEWGGAALLATENAPPRKRA
LYGSFPQLGAPIGFFFANGTFLLLSWLLTDEQFMSWGWRVPFIFSAVLVIIGLYVRVSLHESPVFEKVAKAKKQVKIPLG
TLLTKHVRVTVLGTFIMLATYTLFYIMTVYSMTFSTAAAPVGLGLPRNEVLWMLMMAVIGFGVMVPVAGLLADAFGRRKS
MVIITTLIILFALFAFNPLLGSGNPILVFAFLLLGLSLMGLTFGPMGALLPELFPTEVRYTGASFSYNVASILGASVAPY
IAAWLQTNYGLGAVGLYLAAMAGLTLIALLLTHETRHQSL

Sequences:

>Translated_440_residues
MQATATTLDHEQEYTPINSRNKVLVASLIGTAIEFFDFYIYATAAVIVFPHIFFPQGDPTAATLQSLATFAIAFVARPIG
SAVFGHFGDRVGRKATLVASLLTMGISTVVIGLLPGYATIGIFAPLLLALARFGQGLGLGGEWGGAALLATENAPPRKRA
LYGSFPQLGAPIGFFFANGTFLLLSWLLTDEQFMSWGWRVPFIFSAVLVIIGLYVRVSLHESPVFEKVAKAKKQVKIPLG
TLLTKHVRVTVLGTFIMLATYTLFYIMTVYSMTFSTAAAPVGLGLPRNEVLWMLMMAVIGFGVMVPVAGLLADAFGRRKS
MVIITTLIILFALFAFNPLLGSGNPILVFAFLLLGLSLMGLTFGPMGALLPELFPTEVRYTGASFSYNVASILGASVAPY
IAAWLQTNYGLGAVGLYLAAMAGLTLIALLLTHETRHQSL
>Mature_440_residues
MQATATTLDHEQEYTPINSRNKVLVASLIGTAIEFFDFYIYATAAVIVFPHIFFPQGDPTAATLQSLATFAIAFVARPIG
SAVFGHFGDRVGRKATLVASLLTMGISTVVIGLLPGYATIGIFAPLLLALARFGQGLGLGGEWGGAALLATENAPPRKRA
LYGSFPQLGAPIGFFFANGTFLLLSWLLTDEQFMSWGWRVPFIFSAVLVIIGLYVRVSLHESPVFEKVAKAKKQVKIPLG
TLLTKHVRVTVLGTFIMLATYTLFYIMTVYSMTFSTAAAPVGLGLPRNEVLWMLMMAVIGFGVMVPVAGLLADAFGRRKS
MVIITTLIILFALFAFNPLLGSGNPILVFAFLLLGLSLMGLTFGPMGALLPELFPTEVRYTGASFSYNVASILGASVAPY
IAAWLQTNYGLGAVGLYLAAMAGLTLIALLLTHETRHQSL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family

Homologues:

Organism=Escherichia coli, GI1789941, Length=440, Percent_Identity=100, Blast_Score=865, Evalue=0.0,
Organism=Escherichia coli, GI1788292, Length=442, Percent_Identity=35.5203619909502, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI1790550, Length=452, Percent_Identity=32.7433628318584, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1788942, Length=431, Percent_Identity=31.322505800464, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI87082404, Length=440, Percent_Identity=26.5909090909091, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082231, Length=487, Percent_Identity=24.6406570841889, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHJE_ECOLI (P37643)

Other databases:

- EMBL:   U00039
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   S47743
- RefSeq:   AP_004270.1
- RefSeq:   NP_417980.1
- ProteinModelPortal:   P37643
- STRING:   P37643
- EnsemblBacteria:   EBESCT00000002518
- EnsemblBacteria:   EBESCT00000014343
- GeneID:   948032
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW3491
- KEGG:   eco:b3523
- EchoBASE:   EB2160
- EcoGene:   EG12249
- eggNOG:   COG0477
- GeneTree:   EBGT00050000008829
- HOGENOM:   HBG757988
- OMA:   VARHERV
- ProtClustDB:   CLSK880704
- BioCyc:   EcoCyc:YHJE-MONOMER
- Genevestigator:   P37643
- InterPro:   IPR004736
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005828
- InterPro:   IPR005829
- TIGRFAMs:   TIGR00883

Pfam domain/function: PF07690 MFS_1; PF00083 Sugar_tr; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 47209; Mature: 47209

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS50850 MFS; PS00216 SUGAR_TRANSPORT_1; PS00217 SUGAR_TRANSPORT_2; PS00359 RIBOSOMAL_L11

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1bbaddbc)-; HASH(0x1d3ac674)-; HASH(0x1d865104)-; HASH(0x1c6e6b68)-; HASH(0x1c1ef92c)-; HASH(0x1d76cfb4)-; HASH(0x1d708a14)-; HASH(0x1cfb20d0)-; HASH(0x1c6d12e8)-; HASH(0x1cf4a4f4)-; HASH(0x1c462c44)-; HASH(0x1d7f6cc4)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503