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The map label for this gene is fic

Identifier: 218697042

GI number: 218697042

Start: 3825393

End: 3825995

Strand: Reverse

Name: fic

Synonym: EC55989_3767

Alternate gene names: 218697042

Gene position: 3825995-3825393 (Counterclockwise)

Preceding gene: 218697043

Following gene: 218697041

Centisome position: 74.22

GC content: 53.57

Gene sequence:

>603_bases
ATGAGCGATAAATTCGGCGAAGGGCGCGATCCGTATCTTTATCCTGGCCTTGATATCATGCGTAACCGGCTGAACATCCG
CCAGCAGCAGCGGCTGGAACAGGCCGCTTACGAAATGACGGCGCTGCGTGCTGCGACCATTGAGCTTGGTCCGCTGGTGC
GCGGTTTACCGCATTTGCGCACTATCCATCGCCAGCTGTACCAGGATATTTTCGACTGGGCAGGGCAACTGCGTGAAGTT
GATATTTATCAGGGCGATACGCCGTTCTGCCACTTTGCTTATATCGAAAAAGAGGGCAATGCCCTGATGCAGGATCTGGA
GGAAGAAGGTTATCTGGTTGGCCTGGAGAAAGCGAAGTTCGTCGAGCGGCTGGCGCATTACTATTGTGAAATCAACGTGC
TGCATCCCTTCCGGGTGGGAAGTGGTCTGGCACAGCGGATCTTCTTCGAGCAACTGGCGATTCATGCCGGATATCAACTG
AGCTGGCAGGGTATCGAAAAAGAGGCCTGGAATCAGGCAAATCAGAGTGGAGCAATGGGGGATCTCACCGCGCTGCAGAT
GATATTTAGCAAAGTGGTAAGCGAAGCCGGGGAATCTGAGTAA

Upstream 100 bases:

>100_bases
AATTTTCAGGCCAGTCGCCGTCTTGAAGGCGTCGAGATGCCTTTAGTCACTCTTACTGCCGCAGAGGCTTTAGCGCGCCT
TGAAGAGCTGAGGAGTCACT

Downstream 100 bases:

>100_bases
AATAGCGCGGTTCTTTCGTACCGGAGCCGCCATGATCCTGCTTATAGATAACTACGATTCTTTTACCTGGAACCTCTACC
AGTACTTTTGTGAACTGGGG

Product: cell filamentation protein Fic

Products: NA

Alternate protein names: Cell filamentation protein fic

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MSDKFGEGRDPYLYPGLDIMRNRLNIRQQQRLEQAAYEMTALRAATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREV
DIYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKAKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQL
SWQGIEKEAWNQANQSGAMGDLTALQMIFSKVVSEAGESE

Sequences:

>Translated_200_residues
MSDKFGEGRDPYLYPGLDIMRNRLNIRQQQRLEQAAYEMTALRAATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREV
DIYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKAKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQL
SWQGIEKEAWNQANQSGAMGDLTALQMIFSKVVSEAGESE
>Mature_199_residues
SDKFGEGRDPYLYPGLDIMRNRLNIRQQQRLEQAAYEMTALRAATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREVD
IYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKAKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQLS
WQGIEKEAWNQANQSGAMGDLTALQMIFSKVVSEAGESE

Specific function: Probable adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins. Involved in cell filamentation induced by cyclic AMP. May have some role in cell division

COG id: COG2184

COG function: function code D; Protein involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 fido domain

Homologues:

Organism=Escherichia coli, GI1789761, Length=200, Percent_Identity=100, Blast_Score=415, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FIC_ECOLI (P20605)

Other databases:

- EMBL:   M28363
- EMBL:   M32354
- EMBL:   U18997
- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   S79599
- EMBL:   M55429
- PIR:   D65130
- RefSeq:   AP_004428.1
- RefSeq:   NP_417820.1
- ProteinModelPortal:   P20605
- SMR:   P20605
- DIP:   DIP-9608N
- IntAct:   P20605
- STRING:   P20605
- EnsemblBacteria:   EBESCT00000004008
- EnsemblBacteria:   EBESCT00000004009
- EnsemblBacteria:   EBESCT00000015741
- GeneID:   947872
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW3324
- KEGG:   eco:b3361
- EchoBASE:   EB0303
- EcoGene:   EG10307
- eggNOG:   COG2184
- GeneTree:   EBGT00050000009091
- HOGENOM:   HBG400904
- OMA:   DPYCYPG
- ProtClustDB:   PRK10347
- BioCyc:   EcoCyc:EG10307-MONOMER
- Genevestigator:   P20605
- InterPro:   IPR003812

Pfam domain/function: PF02661 Fic

EC number: NA

Molecular weight: Translated: 22960; Mature: 22829

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS51459 FIDO

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKFGEGRDPYLYPGLDIMRNRLNIRQQQRLEQAAYEMTALRAATIELGPLVRGLPHLR
CCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
TIHRQLYQDIFDWAGQLREVDIYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKAKF
HHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEEECCCHHHHHHHHHCCCEEEHHHHHH
VERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQLSWQGIEKEAWNQANQSGAMG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCCCCH
DLTALQMIFSKVVSEAGESE
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SDKFGEGRDPYLYPGLDIMRNRLNIRQQQRLEQAAYEMTALRAATIELGPLVRGLPHLR
CCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
TIHRQLYQDIFDWAGQLREVDIYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKAKF
HHHHHHHHHHHHHHHHHEEEEEECCCCCEEEEEEEECCCHHHHHHHHHCCCEEEHHHHHH
VERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQLSWQGIEKEAWNQANQSGAMG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCCCCH
DLTALQMIFSKVVSEAGESE
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2546924; 2403545; 9278503; 7549107; 2007139