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The map label for this gene is yhfK

Identifier: 218697039

GI number: 218697039

Start: 3821323

End: 3823425

Strand: Direct

Name: yhfK

Synonym: EC55989_3764

Alternate gene names: 218697039

Gene position: 3821323-3823425 (Clockwise)

Preceding gene: 218697038

Following gene: 218697045

Centisome position: 74.13

GC content: 52.97

Gene sequence:

>2103_bases
TTGTTTCCCCCGATGTGGCGCAGACTGATTTATCACCCCGATATCAACTATGCACTTCGACAAACGCTGGTGCTATGTTT
GCCCGTGGCCGTTGGGTTAATGCTTGGCGAATTACGATTCGGTCTGCTCTTCTCACTCGTTCCTGCCTGTTGCAATATTG
CGGGCCTTGATACGCCTCATAAACGTTTTTTCAAACGCTTAATCATTGGTGCGTCGCTGTTTGCCACCTGTAGCTTGCTG
ACACAGCTACTACTGGCAAAAGATGTTCCTCTGCCCTTTTTGCTGACCGGATTAACGCTGGTACTTGGCGTCACTGCTGA
GCTGGGGCCATTGCACGCTAAATTGCTTCCCGCATCGCTGCTCGCCGCCATTTTTACCCTCAGTCTGGCGGGATATATGC
CGGTCTGGGAACCATTGCTCATCTATGCGTTGGGCACTCTCTGGTACGGATTGTTTAACTGGTTTTGGTTCTGGATCTGG
CGCGAACAACCGCTGCGCGAGTCACTAAGTCTGCTGTACCGTGAACTGGCAGATTATTGTGAAGCCAAATACAGCCTGCT
TACCCAGCACACCGACCCTGAAAAAGCGCTGCCGCCGCTGCTGGTGCGCCAGCAAAAAGCGGTCGATCTAATTACCCAGT
GCTATCAGCAAATGCATATGCTTTCCGCGCAAAATAATACTGACTACAAGCGGATGCTGCGTATTTTCCAGGAGGCGCTG
GATTTACAGGAACATATTTCGGTCAGTTTGCATCAGCCGGAAGAGGTGCAAAAACTGGTCGAGCGTAGCCATGCGGAAGA
AGTTATCCGCTGGAATGCGCAAACCGTCGCCGCTCGCCTGCGCGTGCTGGCTGATGACATTCTTTACCATCGCCTGCCAA
CGCGTTTTACGATGGAAAAGCAAATTGGCGCACTGGAAAAAATCGCCCGCCAGCATCCGGATAATCCGGTTGGGCAATTC
TGCTATTGGCACTTCAGCCGCATTGCCCGCGTGCTGCGCACCCAAAAACCGCTCTATGCCCGTGACTTACTGGCCGATAA
ACAGCGGCGAATGCCGTTACTTCCGGCGCTGAAAAGTTATCTGTCACTAAAGTCTCCGGCGCTACGCAATGCCGGACGAC
TCAGTGTGATGTTAAGCGTTGCCAGCCTGATGGGCACCGCGCTGCATCTGCCGAAGTCGTACTGGATCCTGATGACGGTA
TTGCTGGTGACGCAAAATGGCTATGGCGCAACCCGTTTGAGGATTGTGAATCGCTCCGTGGGAACCGTGGTCGGGTTAAT
CATTGCGGGCGTGGCGCTGCACTTTAAAATTCCCGAAGGTTACACCCTGACCTTGATGCTGATTACCACCCTCGCCAGCT
ACCTGATATTGCGCAAAAACTACGGCTGGGCGACGGTCGGTTTTACCATTACCGCAGTGTATACCCTGCAACTGTTGTGG
CTGAACGGTGAGCAGTACATCCTTCCACGTCTTATCGATACCATTATTGGTTGTTTGATTGCTTTCGGTGGTACCGTCTG
GCTGTGGCCGCAGTGGCAGAGCGGGTTATTGCGTAAAAACGCCCATGATGCTTTAGAAGCCTATCAGGAAGCGATTCGCT
TGATTCTGAGCGAGGACCCGCAACCTACCCCACTGGCCTGGCAGCGAATGCGGGTAAATCAGGCGCATAACACTCTGTAT
AACTCATTGAATCAGGCGATGCAGGAACCAGCGTTCAACAGCCATTATCTGGCAGATATGAAACTGTGGGTAACGCACAG
CCAGTTTATTGTTGAGCATATTAATGCCATGACCACGCTGGCGCGGGAACACCGGGCATTGCCACCTGAACTGGCACAAG
AGTATTTACAGTCTTGTGAAATCGCCATTCAGCGTTGTCAGCAGCGGCTGGAATATGACGAACCGGGGAGTTCTGGCGAT
GCCAATATCATGGATGCGCCGGAGATGCAGCCGCACGAAGGCGCGGCAGGTACGCTGGAGCAGCATTTACAGCGGGTTAT
TGGTCATCTGAACACCATGCACACCATTTCGTCGATGGCATGGCGTCAGCGACCGCATCACGGGATTTGGCTGAGTCGCA
AGTTGCGGGATTCGAAGGCGTAA

Upstream 100 bases:

>100_bases
TTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAATCCCGTCGGAGTGGCGCG
TTACCTGGTAGCGCGCCATT

Downstream 100 bases:

>100_bases
TGCAGGCTAAACCATCGGATAAGGCATTCACGCCGCATCCGACATCTTTTGCCTGATGCTTCGTATTTACGCCCCAATCA
CCTTAGCCACCGCGTGGGCG

Product: conserved hypothetical protein; putative inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 700; Mature: 700

Protein sequence:

>700_residues
MFPPMWRRLIYHPDINYALRQTLVLCLPVAVGLMLGELRFGLLFSLVPACCNIAGLDTPHKRFFKRLIIGASLFATCSLL
TQLLLAKDVPLPFLLTGLTLVLGVTAELGPLHAKLLPASLLAAIFTLSLAGYMPVWEPLLIYALGTLWYGLFNWFWFWIW
REQPLRESLSLLYRELADYCEAKYSLLTQHTDPEKALPPLLVRQQKAVDLITQCYQQMHMLSAQNNTDYKRMLRIFQEAL
DLQEHISVSLHQPEEVQKLVERSHAEEVIRWNAQTVAARLRVLADDILYHRLPTRFTMEKQIGALEKIARQHPDNPVGQF
CYWHFSRIARVLRTQKPLYARDLLADKQRRMPLLPALKSYLSLKSPALRNAGRLSVMLSVASLMGTALHLPKSYWILMTV
LLVTQNGYGATRLRIVNRSVGTVVGLIIAGVALHFKIPEGYTLTLMLITTLASYLILRKNYGWATVGFTITAVYTLQLLW
LNGEQYILPRLIDTIIGCLIAFGGTVWLWPQWQSGLLRKNAHDALEAYQEAIRLILSEDPQPTPLAWQRMRVNQAHNTLY
NSLNQAMQEPAFNSHYLADMKLWVTHSQFIVEHINAMTTLAREHRALPPELAQEYLQSCEIAIQRCQQRLEYDEPGSSGD
ANIMDAPEMQPHEGAAGTLEQHLQRVIGHLNTMHTISSMAWRQRPHHGIWLSRKLRDSKA

Sequences:

>Translated_700_residues
MFPPMWRRLIYHPDINYALRQTLVLCLPVAVGLMLGELRFGLLFSLVPACCNIAGLDTPHKRFFKRLIIGASLFATCSLL
TQLLLAKDVPLPFLLTGLTLVLGVTAELGPLHAKLLPASLLAAIFTLSLAGYMPVWEPLLIYALGTLWYGLFNWFWFWIW
REQPLRESLSLLYRELADYCEAKYSLLTQHTDPEKALPPLLVRQQKAVDLITQCYQQMHMLSAQNNTDYKRMLRIFQEAL
DLQEHISVSLHQPEEVQKLVERSHAEEVIRWNAQTVAARLRVLADDILYHRLPTRFTMEKQIGALEKIARQHPDNPVGQF
CYWHFSRIARVLRTQKPLYARDLLADKQRRMPLLPALKSYLSLKSPALRNAGRLSVMLSVASLMGTALHLPKSYWILMTV
LLVTQNGYGATRLRIVNRSVGTVVGLIIAGVALHFKIPEGYTLTLMLITTLASYLILRKNYGWATVGFTITAVYTLQLLW
LNGEQYILPRLIDTIIGCLIAFGGTVWLWPQWQSGLLRKNAHDALEAYQEAIRLILSEDPQPTPLAWQRMRVNQAHNTLY
NSLNQAMQEPAFNSHYLADMKLWVTHSQFIVEHINAMTTLAREHRALPPELAQEYLQSCEIAIQRCQQRLEYDEPGSSGD
ANIMDAPEMQPHEGAAGTLEQHLQRVIGHLNTMHTISSMAWRQRPHHGIWLSRKLRDSKA
>Mature_700_residues
MFPPMWRRLIYHPDINYALRQTLVLCLPVAVGLMLGELRFGLLFSLVPACCNIAGLDTPHKRFFKRLIIGASLFATCSLL
TQLLLAKDVPLPFLLTGLTLVLGVTAELGPLHAKLLPASLLAAIFTLSLAGYMPVWEPLLIYALGTLWYGLFNWFWFWIW
REQPLRESLSLLYRELADYCEAKYSLLTQHTDPEKALPPLLVRQQKAVDLITQCYQQMHMLSAQNNTDYKRMLRIFQEAL
DLQEHISVSLHQPEEVQKLVERSHAEEVIRWNAQTVAARLRVLADDILYHRLPTRFTMEKQIGALEKIARQHPDNPVGQF
CYWHFSRIARVLRTQKPLYARDLLADKQRRMPLLPALKSYLSLKSPALRNAGRLSVMLSVASLMGTALHLPKSYWILMTV
LLVTQNGYGATRLRIVNRSVGTVVGLIIAGVALHFKIPEGYTLTLMLITTLASYLILRKNYGWATVGFTITAVYTLQLLW
LNGEQYILPRLIDTIIGCLIAFGGTVWLWPQWQSGLLRKNAHDALEAYQEAIRLILSEDPQPTPLAWQRMRVNQAHNTLY
NSLNQAMQEPAFNSHYLADMKLWVTHSQFIVEHINAMTTLAREHRALPPELAQEYLQSCEIAIQRCQQRLEYDEPGSSGD
ANIMDAPEMQPHEGAAGTLEQHLQRVIGHLNTMHTISSMAWRQRPHHGIWLSRKLRDSKA

Specific function: Unknown

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the yccS/yhfK family

Homologues:

Organism=Escherichia coli, GI87082248, Length=700, Percent_Identity=100, Blast_Score=1436, Evalue=0.0,
Organism=Escherichia coli, GI87081808, Length=205, Percent_Identity=33.6585365853659, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHFK_ECOLI (P45537)

Other databases:

- EMBL:   U18997
- EMBL:   U00096
- EMBL:   AP009048
- RefSeq:   AP_004431.1
- RefSeq:   NP_417817.2
- ProteinModelPortal:   P45537
- STRING:   P45537
- EnsemblBacteria:   EBESCT00000002449
- EnsemblBacteria:   EBESCT00000017808
- GeneID:   947866
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5701
- KEGG:   eco:b3358
- EchoBASE:   EB2743
- EcoGene:   EG12906
- eggNOG:   COG1289
- GeneTree:   EBGT00050000009269
- HOGENOM:   HBG417113
- OMA:   DANIMDS
- ProtClustDB:   CLSK880639
- BioCyc:   EcoCyc:G7721-MONOMER
- Genevestigator:   P45537
- InterPro:   IPR006726
- InterPro:   IPR010020
- TIGRFAMs:   TIGR01667

Pfam domain/function: PF04632 FUSC

EC number: NA

Molecular weight: Translated: 79973; Mature: 79973

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1d0c93cc)-; HASH(0x1d086510)-; HASH(0x1bdcf4f0)-; HASH(0x1d0a90cc)-; HASH(0x1d35a8e4)-; HASH(0x1cac233c)-; HASH(0x1cf4ed98)-; HASH(0x1d321f80)-; HASH(0x1d2d6030)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCH
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503