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The map label for this gene is hopD

Identifier: 218697015

GI number: 218697015

Start: 3803287

End: 3803754

Strand: Direct

Name: hopD

Synonym: EC55989_3739

Alternate gene names: 218697015

Gene position: 3803287-3803754 (Clockwise)

Preceding gene: 218696983

Following gene: 218697027

Centisome position: 73.78

GC content: 49.15

Gene sequence:

>468_bases
ATGGACGCTACCCTTCCCTTTCTGATTTTGTACGCTTGTTTATCTGTCCTACTTTTTTTATGGGATGCAAAGCATGGCTT
GTTACCTGACAGATTTACCTGCCCGTTACTCTGGTCAGGTCTTTTGTTCTCTCAGGTTTGTAATCCTGACTGTTTAGCCG
ATGCGTTATGGGGGGCGATTATTGGTTACGGCACATTCGCTGTCATTTACTGGGGGTATCGCATACTGCGTCATAAAGAA
GGATTAGGCTATGGTGATGTGAAGTTTCTCGCCGCCCTTGGTGCCTGGCATACCTGGACCTTCTTGCCACGACTGGTTTT
CCTTGCTGCCTCATTCGCTTGCGGAGCCGTAGTTGTTGGTCTGCTCATGAGAGGAAAAGAGTCATTAAAAAACCCGCTGC
CGTTTGGGCCATTTCTGGCGGCTGCGGGTTTCGTTGTAGGTTGGGATAGTTTGCTGGCAGGCCGTTAA

Upstream 100 bases:

>100_bases
AGCGTTTTTCACCGGAACCAGGTTAACAAATCAGCGATTTCTCTGTTGCTGAGCATCCGGAGTTATTCGATGGTGATACT
CCAATTACAGAGGATGTTTT

Downstream 100 bases:

>100_bases
TCTTTAACTTTTATTTGTGATTGCAGGTAATTTTGTAAACCGATTTTACCGATGAGATCCAGCTCAGTTTCGAGCCAGTC
AATATGACCTTCTTCATCGG

Product: putative bifunctional prepilin peptidase HopD: leader peptidase; methyl transferase (General Secretory Pathway)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MDATLPFLILYACLSVLLFLWDAKHGLLPDRFTCPLLWSGLLFSQVCNPDCLADALWGAIIGYGTFAVIYWGYRILRHKE
GLGYGDVKFLAALGAWHTWTFLPRLVFLAASFACGAVVVGLLMRGKESLKNPLPFGPFLAAAGFVVGWDSLLAGR

Sequences:

>Translated_155_residues
MDATLPFLILYACLSVLLFLWDAKHGLLPDRFTCPLLWSGLLFSQVCNPDCLADALWGAIIGYGTFAVIYWGYRILRHKE
GLGYGDVKFLAALGAWHTWTFLPRLVFLAASFACGAVVVGLLMRGKESLKNPLPFGPFLAAAGFVVGWDSLLAGR
>Mature_155_residues
MDATLPFLILYACLSVLLFLWDAKHGLLPDRFTCPLLWSGLLFSQVCNPDCLADALWGAIIGYGTFAVIYWGYRILRHKE
GLGYGDVKFLAALGAWHTWTFLPRLVFLAASFACGAVVVGLLMRGKESLKNPLPFGPFLAAAGFVVGWDSLLAGR

Specific function: Cleaves Type-4 Fimbrial Leader Sequence And Methylates The N-Terminal (Generally Phe) Residue (By Similarity). [C]

COG id: COG1989

COG function: function code NOU; Type II secretory pathway, prepilin signal peptidase PulO and related peptidases

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A24 family

Homologues:

Organism=Escherichia coli, GI1789732, Length=138, Percent_Identity=41.304347826087, Blast_Score=82, Evalue=1e-17,
Organism=Escherichia coli, GI87082194, Length=124, Percent_Identity=37.9032258064516, Blast_Score=70, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HOPD_ECOLX (O68932)

Other databases:

- EMBL:   AF058450
- MEROPS:   A24.003
- GO:   GO:0016020
- InterPro:   IPR014032
- InterPro:   IPR000045
- PRINTS:   PR00864

Pfam domain/function: PF01478 Peptidase_A24

EC number: 3.4.23.43

Molecular weight: Translated: 16984; Mature: 16984

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDATLPFLILYACLSVLLFLWDAKHGLLPDRFTCPLLWSGLLFSQVCNPDCLADALWGAI
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
IGYGTFAVIYWGYRILRHKEGLGYGDVKFLAALGAWHTWTFLPRLVFLAASFACGAVVVG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMRGKESLKNPLPFGPFLAAAGFVVGWDSLLAGR
HHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDATLPFLILYACLSVLLFLWDAKHGLLPDRFTCPLLWSGLLFSQVCNPDCLADALWGAI
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
IGYGTFAVIYWGYRILRHKEGLGYGDVKFLAALGAWHTWTFLPRLVFLAASFACGAVVVG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLMRGKESLKNPLPFGPFLAAAGFVVGWDSLLAGR
HHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA